ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Kits ELISA

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. De plus, nous expédions ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Anticorps (244) et ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Protéines (7) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795
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Top ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Kits ELISA sur anticorps-enligne.fr

Showing 3 out of 17 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Rat 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Connectez-vous pour afficher 13 to 17 Days
772,39 €
Détails
Humain 1.0 ng/mL 50-1000 ng/mL   96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
Détails
Souris 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 11 to 15 Days
452,57 €
Détails

Plus Kits ELISA pour ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 partenaires d'interaction

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (Montrer ABCB4 Kits ELISA), Bcrp (Montrer ABCG2 Kits ELISA) and Mrp1 (Montrer ABCC1 Kits ELISA) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. A subset of virus-specific CD161 (Montrer KLRB1 Kits ELISA)(+) T cells selectively express the multidrug transporter MDR1 and are resistant to chemotherapy in acute myeloid leukemia (Montrer BCL11A Kits ELISA).

  2. Primary CD4 (Montrer CD4 Kits ELISA)+P-gphigh T cells eliminate intracellular raltegravir more readily than P-gplow cells and HIV-1 viraemia correlates with P-gp (Montrer ABCB4 Kits ELISA) overall activity; specific CD4 (Montrer CD4 Kits ELISA)+P-gphigh T cell subsets could facilitate the persistence of viral replication in vivo and ultimately promote the appearance of drug resistance

  3. We observed an association between ABCB1 3435 T/T and lower grade of toxicities (p=0.05) in patients receiving taxanes for breast cancer. No other associations were found for CYP (Montrer PPIG Kits ELISA) 3A4 *1B, 3A5*3 and ABCB1 C1236T.

  4. that residual SWI (Montrer SMARCA1 Kits ELISA)/SNF (Montrer SNRPA Kits ELISA) complexes lacking SMARCB1 (Montrer SMARCB1 Kits ELISA) are vital determinants of drug sensitivity, not just to TOP2A (Montrer TOP2A Kits ELISA)-targeted agents, but to the much broader range of cancer drugs effluxed by ABCB1.

  5. Patients with active rheumatoid arthritis have an increased function of ABCB1 and ABCG2 (Montrer ABCG2 Kits ELISA), and disease activity is the main determinant of this phenomena.

  6. the induction of P-gp (Montrer ABCB4 Kits ELISA) expression is causally associated with the expression of nestin (Montrer NES Kits ELISA) in leukemia cells

  7. High MDR1 expression is associated with Cisplatin Resistance in Gastric Cancer.

  8. overexpression is a key Initiator of resistance to tyrosine kinase (Montrer TXK Kits ELISA) inhibitors in chronic myeloid leukemia (Montrer BCL11A Kits ELISA) cell lines

  9. The results indicate that human BCRP (Montrer ABCG2 Kits ELISA) and not human P-gp (Montrer ABCB4 Kits ELISA) is involved in benzylpenicillin transport.

  10. Study suggests thatSNPs of 1236C > T contributed to an individual variation in anesthetic effects that follow the pediatric tonsillectomy, and also it was figured out that the patients with the MDR1 1236C > T CC (Montrer CYCT Kits ELISA) genotype displayed superior anesthetic effects compared to those patients who possessed the CT + TT genotype

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (Montrer ABCB4 Kits ELISA) ATPase (Montrer DNAH8 Kits ELISA) activity

  2. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  3. Chrysosplenetin inhibited P-gp (Montrer ABCB4 Kits ELISA) activity and reverse the up-regulated P-gp (Montrer ABCB4 Kits ELISA) and MDR1 (Montrer ABCB4 Kits ELISA) levels induced by artemisinin.

  4. Tamsulosin and tolterodine with P-gp (Montrer ABCB4 Kits ELISA) gene expression and activity in an enantiomer-specific way.

  5. Pgp (Montrer ABCB4 Kits ELISA)-coupled ATPase (Montrer DNAH8 Kits ELISA) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  6. Data show that human transgenic mutant huntingtin (Montrer HTT Kits ELISA) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (Montrer ABCB4 Kits ELISA)) which suggests that MDR1 (Montrer ABCB4 Kits ELISA) might be a potential therapeutic target for Huntington's disease.

  7. In vitro and in vivo downregulation of the ATP binding cassette transporter (Montrer ABCC3 Kits ELISA) B1 by the HMG-CoA reductase (Montrer HMGCR Kits ELISA) inhibitor simvastatin

  8. Efficient chemoprotection of CDD (Montrer CDA Kits ELISA) and MDR1 (Montrer ABCB4 Kits ELISA) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (Montrer FOXC1 Kits ELISA)-C and anthracycline application

  9. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1-1Delta mutant mice following exposure to various P-gp (Montrer ABCB4 Kits ELISA) substrates.

  10. Data indicate that the brain penetration of ABT-888 in both Abcb1a (Montrer ABCB4 Kits ELISA)/1b-/- and Abcb1a (Montrer ABCB4 Kits ELISA)/1b-/-;Abcg2 (Montrer ABCG2 Kits ELISA)-/- mice was significantly higher than in wild-type mice.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) profil antigène

Antigen Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (abcb1) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1A (Abcb1a) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) anticorps
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) anticorps
  • malic enzyme complex, mitochondrial (Mod2) anticorps
  • ABC20 anticorps
  • ABCB1 anticorps
  • Cd243 anticorps
  • CLCS anticorps
  • GP170 anticorps
  • Mdr anticorps
  • Mdr-1 anticorps
  • Mdr1 anticorps
  • Mdr1a anticorps
  • Mdr1b anticorps
  • Mod-2 anticorps
  • Mod-2r anticorps
  • Mod-2s anticorps
  • Mod2-r anticorps
  • Mod2-s anticorps
  • p-gp anticorps
  • PGP1 anticorps
  • Pgy-1 anticorps
  • Pgy1 anticorps
  • xemdr anticorps

Protein level used designations for ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPECIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
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