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ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Kits ELISA

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. De plus, nous expédions ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Anticorps (252) et ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Protéines (8) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795
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Top ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Kits ELISA sur anticorps-enligne.fr

Showing 6 out of 16 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Rat 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Connectez-vous pour afficher 9 to 12 Days
772,39 €
Détails
Cobaye 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
Détails
Humain 1.0 ng/mL 50-1000 ng/mL   96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
Détails
Singe 1.0 ng/mL 50-1000 ng/mL   96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
Détails
Chien 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 9 to 12 Days
673,47 €
Détails
Souris 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 9 to 12 Days
860,54 €
Détails

Plus Kits ELISA pour ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 partenaires d'interaction

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (Montrer ABCB4 Kits ELISA), Bcrp (Montrer ABCG2 Kits ELISA) and Mrp1 (Montrer ABCC1 Kits ELISA) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. Study investigated the effect of MDR1, CYP2D6 (Montrer CYP2D6 Kits ELISA) and CYP2C19 (Montrer CYP2C19 Kits ELISA) gene polymorphisms on prophylactic therapy response in migraine patients, suggested that migraine patients who receive topiramate prophylactic treatment should be assessed for the presence of the MDR1 C3435T polymorphism

  2. The GG and TT genotypes in CYP3A5 (Montrer CYP3A5 Kits ELISA)*3 and ABCB1 C3435T, respectively, were linked with higher TPC.

  3. The study revealed the correlation between ABCB1 DNA promoter methylation with rs1128503 and rs2032582 polymorphisms in malaria and was related to increased expression of ABCB1 protein levels in complicated malaria group when compared to uncomplicated malaria and control groups.

  4. findings suggest that Tetrandrine prevents paclitaxel-induced MDR by inhibiting Pgp (Montrer PGPEP1 Kits ELISA) overexpression through a mechanism that may involve the inhibition of NF-kappaB (Montrer NFKB1 Kits ELISA) signaling in osteosarcoma.

  5. Results find that ABCB1 is a target of miR (Montrer MLXIP Kits ELISA)-9 and reverses the effect of miR (Montrer MLXIP Kits ELISA)-9-mediated chemoresistance in K562 chronic myelogenous leukemia cells.

  6. findings suggest that osimertinib, a clinically-approved third-generation EGFR (Montrer EGFR Kits ELISA) TKI, can reverse ABCB1-mediated MDR, which supports the combination therapy with osimertinib and ABCB1 substrates may potentially be a novel therapeutic stategy in ABCB1-positive drug resistant cancers.

  7. Subcellular distribution of P-gp (Montrer ABCB4 Kits ELISA) and subsequent downregulation by pristimerin contribute to overcoming ABCB1-mediated chemotherapeutic drug resistance. Our findings suggested inducing the decrease of P-gp (Montrer ABCB4 Kits ELISA) membrane protein could be a new promising alternative therapeutic strategy in ABCB1-mediated Multidrug resistance.

  8. Rack1 (Montrer GNB2L1 Kits ELISA) regulated P-Glycoprotein activity, which was necessary for adriamycin-induced P-Glycoprotein - mediated phosphorylation of Anxa2 (Montrer ANXA2 Kits ELISA) and Erk1/2 (Montrer MAPK1/3 Kits ELISA).

  9. we found that the C3435T MDR1 polymorphism does not affect blood levels of cortisol or ACTH (Montrer POMC Kits ELISA) in healthy Japanese males. The effect size at alpha = 0.05 and at power 0.80 in the present sample size was 0.176 Thus, the present study suggests that the C3435T MDR1 polymorphism does not have a great impact on blood levels of cortisol or ACTH (Montrer POMC Kits ELISA).

  10. ABCB1 1236C/T variants might play a role in the risk of Parkinson's disease, whereas ABCB1 3435C/T polymorphisms might not contribute to susceptibility to disease (Meta-Analysis)

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. Chrysosplenetin inhibited P-gp (Montrer ABCB4 Kits ELISA) activity and reverse the up-regulated P-gp (Montrer ABCB4 Kits ELISA) and MDR1 (Montrer ABCB4 Kits ELISA) levels induced by artemisinin.

  2. Tamsulosin and tolterodine with P-gp (Montrer ABCB4 Kits ELISA) gene expression and activity in an enantiomer-specific way.

  3. Pgp (Montrer ABCB4 Kits ELISA)-coupled ATPase (Montrer DNAH8 Kits ELISA) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  4. Data show that human transgenic mutant huntingtin (Montrer HTT Kits ELISA) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (Montrer ABCB4 Kits ELISA)) which suggests that MDR1 (Montrer ABCB4 Kits ELISA) might be a potential therapeutic target for Huntington's disease.

  5. In vitro and in vivo downregulation of the ATP binding cassette transporter (Montrer ABCC3 Kits ELISA) B1 by the HMG-CoA reductase (Montrer HMGCR Kits ELISA) inhibitor simvastatin

  6. Efficient chemoprotection of CDD (Montrer CDA Kits ELISA) and MDR1 (Montrer ABCB4 Kits ELISA) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (Montrer FOXC1 Kits ELISA)-C and anthracycline application

  7. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1-1Delta mutant mice following exposure to various P-gp (Montrer ABCB4 Kits ELISA) substrates.

  8. Data indicate that the brain penetration of ABT-888 in both Abcb1a (Montrer ABCB4 Kits ELISA)/1b-/- and Abcb1a (Montrer ABCB4 Kits ELISA)/1b-/-;Abcg2 (Montrer ABCG2 Kits ELISA)-/- mice was significantly higher than in wild-type mice.

  9. Expression of Abcb1 at the blood-brain and blood-spinal barriers is upregulated by Nrf2 (Montrer NFE2L2 Kits ELISA).

  10. The improved structures of Pgp reveal important implications for polyspecific drug recognition in the form of a high concentration of aromatic residues in the drug translocation pathway that is most conserved among mammalian orthologs.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) profil antigène

Antigen Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (abcb1) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1A (Abcb1a) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) anticorps
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) anticorps
  • malic enzyme complex, mitochondrial (Mod2) anticorps
  • ABC20 anticorps
  • ABCB1 anticorps
  • Cd243 anticorps
  • CLCS anticorps
  • GP170 anticorps
  • Mdr anticorps
  • Mdr-1 anticorps
  • Mdr1 anticorps
  • Mdr1a anticorps
  • Mdr1b anticorps
  • Mod-2 anticorps
  • Mod-2r anticorps
  • Mod-2s anticorps
  • Mod2-r anticorps
  • Mod2-s anticorps
  • p-gp anticorps
  • PGP1 anticorps
  • Pgy-1 anticorps
  • Pgy1 anticorps
  • xemdr anticorps

Protein level used designations for ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPECIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
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