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anti-Abhydrolase Domain Containing 5 (ABHD5) Anticorps

The protein encoded by ABHD5 belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. De plus, nous expédions ABHD5 Protéines (9) et ABHD5 Kits (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ABHD5 51099 Q8WTS1
ABHD5 67469 Q9DBL9
ABHD5 316122 Q6QA69
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Top anti-ABHD5 Anticorps sur anticorps-enligne.fr

Showing 10 out of 67 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Poulet Lapin Inconjugué IHC, WB WB Suggested Anti-ABHD5 Antibody Titration: 0.2-1 ug/mlPositive Contro... 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 6 to 8 Days
288,68 €
Détails
Humain Chèvre Inconjugué ELISA, WB ABIN190850 (1µg/ml) staining of A431 cell line lysate (35µg protein in... 100 μg Connectez-vous pour afficher 3 to 4 Days
341,55 €
Détails
Humain Souris Inconjugué WB ABHD5 monoclonal antibody (M02), clone 4B12 Western Blot analysis of A... 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails
Chien Chèvre Inconjugué WB 0.1 mg Connectez-vous pour afficher 8 to 10 Days
357,50 €
Détails
Humain Souris Inconjugué WB Western Blot analysis of ABHD5 expression in transfected 293T cell lin... 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails
Humain Souris Inconjugué ELISA, WB ABHD5 monoclonal antibody (M02), clone 4B12 Western Blot analysis of A... Detection limit for recombinant GST tagged ABHD5 is 0.3 ng/ml as a cap... 100 μg Connectez-vous pour afficher 8 to 9 Days
369,60 €
Détails
Humain Lapin Inconjugué ICC, IF, WB   25 μL Connectez-vous pour afficher 6 to 8 Days
187,00 €
Détails
Humain Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 6 to 8 Days
337,56 €
Détails
Humain Souris Inconjugué IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to ABHD5 on formalin-fixed par... Western Blot analysis of ABHD5 expression in transfected 293T cell lin... 100 μg Connectez-vous pour afficher 8 to 9 Days
369,60 €
Détails

ABHD5 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité
Human , , , ,
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Mouse (Murine) , , , ,
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Rat (Rattus) , , , ,
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anti-ABHD5 Anticorps mieux référencés

  1. Human Monoclonal ABHD5 Primary Antibody pour IHC (p), ELISA - ABIN565526 : Kinney, Qiao, Levaugh, Shao: B56alpha/protein phosphatase 2A inhibits adipose lipolysis in high-fat diet-induced obese mice. dans Endocrinology 2010 (PubMed)
    Show all 11 references for ABIN565526

  2. Human Monoclonal ABHD5 Primary Antibody pour WB - ABIN395090 : Lan, Fu, Liu, Huang, Chang, Liu, Peng, Chen: High frequency of ETFDH c.250G>A mutation in Taiwanese patients with late-onset lipid storage myopathy. dans Clinical genetics 2010 (PubMed)
    Show all 5 references for ABIN395090

  3. Human Monoclonal ABHD5 Primary Antibody pour WB - ABIN396214 : Schweiger, Lass, Zimmermann, Eichmann, Zechner: Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5. dans American journal of physiology. Endocrinology and metabolism 2009 (PubMed)
    Show all 5 references for ABIN396214

  4. Human Monoclonal ABHD5 Primary Antibody pour ELISA, WB - ABIN565527 : Watt, van Denderen, Castelli, Bruce, Hoy, Kraegen, Macaulay, Kemp: Adipose triglyceride lipase regulation of skeletal muscle lipid metabolism and insulin responsiveness. dans Molecular endocrinology (Baltimore, Md.) 2008 (PubMed)
    Show all 3 references for ABIN565527

  5. Human Polyclonal ABHD5 Primary Antibody pour ELISA, WB - ABIN190850 : Lass, Zimmermann, Haemmerle, Riederer, Schoiswohl, Schweiger, Kienesberger, Strauss, Gorkiewicz, Zechner: Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome. dans Cell metabolism 2006 (PubMed)
    Show all 2 references for ABIN190850

  6. Human Polyclonal ABHD5 Primary Antibody pour ICC, IF - ABIN258374 : Yamaguchi, Omatsu, Matsushita, Osumi: CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome. dans The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for ABIN258374

  7. Dog (Canine) Polyclonal ABHD5 Primary Antibody pour WB - ABIN374842 : Koltes, Spurlock: Coordination of lipid droplet-associated proteins during the transition period of Holstein dairy cows. dans Journal of dairy science 2011 (PubMed)

  8. Chicken Polyclonal ABHD5 Primary Antibody pour IHC, WB - ABIN2775425 : Bruno, Bertini, Di Rocco, Cassandrini, Ruffa, De Toni, Seri, Spada, Li Volti, DAmico, Trucco, Arca, Casali, Angelini, Dimauro, Minetti: Clinical and genetic characterization of Chanarin-Dorfman syndrome. dans Biochemical and biophysical research communications 2008 (PubMed)

Plus d’anticorps contre ABHD5 partenaires d’interaction

Human Abhydrolase Domain Containing 5 (ABHD5) interaction partners

  1. Authors show that rat ATGL (Montrer PNPLA2 Anticorps), coactivated by rat CGI-58, efficiently hydrolyzes triglycerides and retinyl ester.

  2. novel ABHD5 truncating variant in a twenty nine month old female child, who presented with icthyosiform erythroderma.

  3. simultaneous tryptophan alanine permutations in both arms abolish localization and activity of CGI-58 as opposed to tryptophan substitutions that occur in only one arm.

  4. this study presents clinical and molecular data of four affected relatives with Chanarin-Dorfman syndrome homozygous for a N209X mutation in ABHD5, and provides a short review by comparing patients with N209X homozygous mutations to patients with other ABHD5 mutations.

  5. PLIN5 (Montrer PLIN5 Anticorps) was significantly colocated with ATGL (Montrer PNPLA2 Anticorps), mitochondria and CGI-58, indicating a close association between the key lipolytic effectors in resting skeletal muscle.

  6. -mediated phosphorylation of CGI-58 is required for dispersion of CGI-58 from perilipin (Montrer PLIN1 Anticorps) 1A-coated lipid droplets

  7. Abhd5 expression falls substantially and correlates negatively with malignant features in human colorectal cancer.

  8. Findings indicate a molecular mechanisms by which lysophosphatidic acid acyltransferase (Montrer MBOAT2 Anticorps) CGI-58 regulates lipid homeostasis.

  9. ABHD5, PGRMC1 (Montrer PGRMC1 Anticorps) and SQS (Montrer FDFT1 Anticorps) are novel markers for sebaceous carcinoma and can reliably distinguish sebaceous neoplasms from non-sebaceous tumors, specifically BCC with clear cell features.

  10. A report of two Chanarin-Dorfman syndrome sisters with severe steatohepatitis and decompensated cirrhosis due to steatohepatitis in whom the clinical presentation developed due to a new mutation in ABHD5 gene.

Mouse (Murine) Abhydrolase Domain Containing 5 (ABHD5) interaction partners

  1. we identify adipocyte-type fatty acid-binding protein (A-Fabp (Montrer FABP4 Anticorps)) and other members of the fatty acid-binding protein (Fabp (Montrer FABP Anticorps)) family as interaction partners of Cgi-58.

  2. Data (including data from studies in atherosclerotic knockout mice) suggest CGI58-deficient macrophages store-up triglyceride-rich droplets and have reduced phagocytic capacity, comparable to Atgl- (adipose triglyceride lipase (Montrer PNPLA2 Anticorps)-)deficient macrophages.

  3. -mediated phosphorylation of CGI-58 is required for dispersion of CGI-58 from perilipin (Montrer PLIN1 Anticorps) 1A-coated lipid droplets

  4. Muscle CGI-58 deficiency causes cardiac dysfunction and fat deposition in oxidative muscles but induces a series of favorable metabolic changes in mice fed a high-fat diet.

  5. intestinal CGI-58 is required for efficient postprandial lipoprotein-TG secretion and for maintaining hepatic and plasma lipid homeostasis.

  6. CGI-58 transgenic/ApoE (Montrer APOE Anticorps)-/- mice exhibited an anti-atherosclerosis phenotype compared with wild type (WT) controls (CGI-58 WT/ApoE (Montrer APOE Anticorps)-/-), illustrated by less plaque area in aortic roots.

  7. The anti-lipolytic activity of the HCV core protein alters ATGL (Montrer PNPLA2 Anticorps) binding to CGI-58 and enhances the association of both proteins with lipid droplets.

  8. These data thus identified a vicious cycle (IL-1beta (Montrer IL1B Anticorps)-SOCS3 (Montrer SOCS3 Anticorps)-FOXO1 (Montrer FOXO1 Anticorps)-IL-1beta (Montrer IL1B Anticorps)) that amplifies IL-1beta (Montrer IL1B Anticorps) secretion and is initiated by CGI-58 deficiency-induced activation of the NLRP3 (Montrer NLRP3 Anticorps) inflammasome in macrophages.

  9. Perilipins 2 and 3 lack a carboxy-terminal domain present in perilipin 1 (Montrer PLIN1 Anticorps) involved in sequestering ABHD5 and suppressing basal lipolysis.

  10. The CGI-58 deficiency in the liver directly causes not only hepatic steatosis but also steatohepatitis and fibrosis.

Pig (Porcine) Abhydrolase Domain Containing 5 (ABHD5) interaction partners

  1. These findings suggest that CGI-58 may be a new target for enhancing the quality of pork products as well as offering the potential of CGI-58 for human obesity treatment.

ABHD5 profil antigène

Profil protéine

The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation.

Gene names and symbols associated with ABHD5

  • abhydrolase domain containing 5 (ABHD5) anticorps
  • abhydrolase domain containing 5 (abhd5) anticorps
  • abhydrolase domain containing 5a (abhd5a) anticorps
  • abhydrolase domain containing 5 (LOC100229229) anticorps
  • abhydrolase domain containing 5 (LOC100350162) anticorps
  • abhydrolase domain containing 5 (Abhd5) anticorps
  • 1300003D03Rik anticorps
  • 2010002J10Rik anticorps
  • abhd5 anticorps
  • CDS anticorps
  • CGI-58 anticorps
  • CGI58 anticorps
  • IECN2 anticorps
  • IECN5 anticorps
  • NCIE2 anticorps

Protein level used designations for ABHD5

abhydrolase domain containing 5 , CGI58 protein , 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 , abhydrolase domain-containing protein 5 , lipid droplet-binding protein CGI-58 , alpha/beta hydrolase domain-containing 5 , lipid droplet binding protein , Abhydrolase domain-containing protein 5

GENE ID SPECIES
460303 Pan troglodytes
549643 Xenopus (Silurana) tropicalis
566493 Danio rerio
100066775 Equus caballus
100229229 Taeniopygia guttata
100350162 Oryctolagus cuniculus
100125355 Ovis aries
51099 Homo sapiens
67469 Mus musculus
485570 Canis lupus familiaris
497624 Sus scrofa
535588 Bos taurus
316122 Rattus norvegicus
446400 Xenopus laevis
420673 Gallus gallus
100174407 Pongo abelii
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