anti-Abhydrolase Domain Containing 5 (ABHD5) Anticorps

The protein encoded by ABHD5 belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. De plus, nous expédions ABHD5 Protéines (9) et ABHD5 Kits (7) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ABHD5 51099 Q8WTS1
ABHD5 67469 Q9DBL9
ABHD5 316122 Q6QA69
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Top anti-ABHD5 Anticorps sur anticorps-enligne.fr

Showing 10 out of 77 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB <b>WB Suggested Anti-ABHD5 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>MCF7 cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Chèvre Inconjugué ELISA, WB ABIN190850 (1µg/ml) staining of A431 cell line lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 3 to 4 Days
349,82 €
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 6 to 8 Days
288,68 €
Détails
Humain Lapin Inconjugué SimWes, WB Western Blot: Abhd5 Antibody [ABIN2583726] - Western Blot on Abhd5 overexpression lysates (NBL1-07199). Western Blot: Abhd5 Antibody [ABIN2583726] - Western Blot on MCF7 cell lysates. 0.1 mL Connectez-vous pour afficher 3 to 5 Days
363,75 €
Détails
Boeuf (Vache) Chèvre Inconjugué ICC, IF, ELISA, WB Western Blot: ABHD5 Antibody [ABIN252915] - ABIN252915 (1µg/ml) staining of A431 cell line lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: Abhd5 Antibody [ABIN2529150] - Analysis of CGI58 in NIH3T3 lysate (35ug protein in RIPA buffer) using this antibody at 0.2 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Connectez-vous pour afficher 3 to 5 Days
388,75 €
Détails
Humain Souris Inconjugué WB ABHD5 monoclonal antibody (M02), clone 4B12 Western Blot analysis of ABHD5 expression in A-431. 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails
Humain Souris Inconjugué WB Western Blot analysis of ABHD5 expression in transfected 293T cell line by ABHD5 monoclonal antibody (M01), clone 1F3. Lane 1: ABHD5 transfected lysate(39 KDa). Lane 2: Non-transfected lysate. Immunoperoxidase of monoclonal antibody to ABHD5 on formalin-fixed paraffin-embedded human small Intestine (antibody concentration 3 µg/mL). 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails
Humain Lapin Inconjugué IHC (p), WB   100 μg Connectez-vous pour afficher 8 to 11 Days
340,48 €
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 11 to 14 Days
583,17 €
Détails
Humain Souris Inconjugué ELISA, WB ABHD5 monoclonal antibody (M02), clone 4B12 Western Blot analysis of ABHD5 expression in A-431 . Detection limit for recombinant GST tagged ABHD5 is 0.3 ng/ml as a capture antibody. 100 μg Connectez-vous pour afficher 7 to 8 Days
369,60 €
Détails

ABHD5 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human ,
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Mouse (Murine) ,
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Rat (Rattus) ,
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anti-ABHD5 Anticorps mieux référencés

  1. Human Polyclonal ABHD5 Primary Antibody pour SimWes, WB - ABIN258372 : Yamaguchi, Omatsu, Matsushita, Osumi: CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome. dans The Journal of biological chemistry 2004 (PubMed)
    Show all 21 Pubmed References

  2. Human Monoclonal ABHD5 Primary Antibody pour IHC (p), ELISA - ABIN565526 : Kinney, Qiao, Levaugh, Shao: B56alpha/protein phosphatase 2A inhibits adipose lipolysis in high-fat diet-induced obese mice. dans Endocrinology 2010 (PubMed)
    Show all 11 Pubmed References

  3. Human Monoclonal ABHD5 Primary Antibody pour ELISA, WB - ABIN565527 : Watt, van Denderen, Castelli, Bruce, Hoy, Kraegen, Macaulay, Kemp: Adipose triglyceride lipase regulation of skeletal muscle lipid metabolism and insulin responsiveness. dans Molecular endocrinology (Baltimore, Md.) 2008 (PubMed)
    Show all 3 Pubmed References

  4. Polyclonal ABHD5 Primary Antibody pour WB - ABIN540799 : Subramanian, Rothenberg, Gomez, Cohen, Garcia, Bhattacharyya, Shapiro, Dolios, Wang, Lisanti, Brasaemle: Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytes. dans The Journal of biological chemistry 2004 (PubMed)
    Show all 3 Pubmed References

  5. Cow (Bovine) Polyclonal ABHD5 Primary Antibody pour ICC, IF - ABIN252915 : Sitnick, Basantani, Cai, Schoiswohl, Yazbeck, Distefano, Ritov, DeLany, Schreiber, Stolz, Gardner, Kienesberger, Pulinilkunnil, Zechner, Goodpaster, Coen, Kershaw: Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity. dans Diabetes 2013 (PubMed)
    Show all 2 Pubmed References

  6. Human Polyclonal ABHD5 Primary Antibody pour ELISA, WB - ABIN190850 : Lass, Zimmermann, Haemmerle, Riederer, Schoiswohl, Schweiger, Kienesberger, Strauss, Gorkiewicz, Zechner: Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome. dans Cell metabolism 2006 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre ABHD5 partenaires d’interaction

Human Abhydrolase Domain Containing 5 (ABHD5) interaction partners

  1. ABHD5 possesses a PNPLA2 (Montrer PNPLA2 Anticorps)-independent function in regulating autophagy and tumorigenesis.

  2. These results indicate that HCV taps (Montrer ASPRV1 Anticorps) into the lipid droplet triglyceride reservoir usurping ABHD5 lipase (Montrer LIPG Anticorps) cofactor function

  3. Case Report: novel ABHD5 mutation, c.838C > T (p.Arg280*), in trans with p.Arg234* in a Chinese patient with very mild Dorfman-Chanarin syndrome.

  4. Authors show that rat ATGL (Montrer PNPLA2 Anticorps), coactivated by rat CGI-58, efficiently hydrolyzes triglycerides and retinyl ester.

  5. novel ABHD5 truncating variant in a twenty nine month old female child, who presented with icthyosiform erythroderma.

  6. simultaneous tryptophan alanine permutations in both arms abolish localization and activity of CGI-58 as opposed to tryptophan substitutions that occur in only one arm.

  7. this study presents clinical and molecular data of four affected relatives with Chanarin-Dorfman syndrome homozygous for a N209X mutation in ABHD5, and provides a short review by comparing patients with N209X homozygous mutations to patients with other ABHD5 mutations.

  8. PLIN5 (Montrer PLIN5 Anticorps) was significantly colocated with ATGL (Montrer PNPLA2 Anticorps), mitochondria and CGI-58, indicating a close association between the key lipolytic effectors in resting skeletal muscle.

  9. -mediated phosphorylation of CGI-58 is required for dispersion of CGI-58 from perilipin (Montrer PLIN1 Anticorps) 1A-coated lipid droplets

  10. Abhd5 expression falls substantially and correlates negatively with malignant features in human colorectal cancer.

Mouse (Murine) Abhydrolase Domain Containing 5 (ABHD5) interaction partners

  1. ABHD5 possesses a PNPLA2 (Montrer PNPLA2 Anticorps)-independent function in regulating autophagy and tumorigenesis.

  2. omega-O-AcylCer and CLE (Montrer C14orf166 Anticorps) formation critically depend on CGI-58 expression in differentiated keratinocytes.

  3. These results demonstrate that macrophage CGI-58 enhances PPAR-gamma (Montrer PPARG Anticorps) signaling and thus suppresses inflammatory responsiveness and mitochondrial dysfunction in macrophages.

  4. Here, we identify synthetic ligands that release ABHD5 from PLIN1 (Montrer PLIN1 Anticorps) or PLIN5 (Montrer PLIN5 Anticorps) without PKA activation and rapidly activate adipocyte and muscle lipolysis.

  5. we identify adipocyte-type fatty acid-binding protein (A-Fabp (Montrer FABP4 Anticorps)) and other members of the fatty acid-binding protein (Fabp (Montrer FABP Anticorps)) family as interaction partners of Cgi-58.

  6. Data (including data from studies in atherosclerotic knockout mice) suggest CGI58-deficient macrophages store-up triglyceride-rich droplets and have reduced phagocytic capacity, comparable to Atgl- (adipose triglyceride lipase (Montrer PNPLA2 Anticorps)-)deficient macrophages.

  7. -mediated phosphorylation of CGI-58 is required for dispersion of CGI-58 from perilipin (Montrer PLIN1 Anticorps) 1A-coated lipid droplets

  8. Muscle CGI-58 deficiency causes cardiac dysfunction and fat deposition in oxidative muscles but induces a series of favorable metabolic changes in mice fed a high-fat diet.

  9. intestinal CGI-58 is required for efficient postprandial lipoprotein-TG secretion and for maintaining hepatic and plasma lipid homeostasis.

  10. CGI-58 transgenic/ApoE (Montrer APOE Anticorps)-/- mice exhibited an anti-atherosclerosis phenotype compared with wild type (WT) controls (CGI-58 WT/ApoE (Montrer APOE Anticorps)-/-), illustrated by less plaque area in aortic roots.

Pig (Porcine) Abhydrolase Domain Containing 5 (ABHD5) interaction partners

  1. These findings suggest that CGI-58 may be a new target for enhancing the quality of pork products as well as offering the potential of CGI-58 for human obesity treatment.

ABHD5 profil antigène

Profil protéine

The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation.

Gene names and symbols associated with ABHD5

  • abhydrolase domain containing 5 (ABHD5) anticorps
  • abhydrolase domain containing 5 (abhd5) anticorps
  • abhydrolase domain containing 5a (abhd5a) anticorps
  • abhydrolase domain containing 5 (LOC100229229) anticorps
  • abhydrolase domain containing 5 (LOC100350162) anticorps
  • abhydrolase domain containing 5 (Abhd5) anticorps
  • 1300003D03Rik anticorps
  • 2010002J10Rik anticorps
  • abhd5 anticorps
  • CDS anticorps
  • CGI-58 anticorps
  • CGI58 anticorps
  • IECN2 anticorps
  • IECN5 anticorps
  • NCIE2 anticorps

Protein level used designations for ABHD5

abhydrolase domain containing 5 , CGI58 protein , 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 , abhydrolase domain-containing protein 5 , lipid droplet-binding protein CGI-58 , alpha/beta hydrolase domain-containing 5 , lipid droplet binding protein , Abhydrolase domain-containing protein 5

GENE ID SPECIES
460303 Pan troglodytes
549643 Xenopus (Silurana) tropicalis
566493 Danio rerio
100066775 Equus caballus
100229229 Taeniopygia guttata
100350162 Oryctolagus cuniculus
100125355 Ovis aries
51099 Homo sapiens
67469 Mus musculus
485570 Canis lupus familiaris
497624 Sus scrofa
535588 Bos taurus
316122 Rattus norvegicus
446400 Xenopus laevis
420673 Gallus gallus
100174407 Pongo abelii
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