anti-Amyloid beta (Abeta) Anticorps

Abeta encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. De plus, nous expédions beta Amyloid Kits (12) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
Abeta 351 P05067
Abeta 54226 P08592
Abeta 11820 P12023
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Top anti-beta Amyloid Anticorps sur anticorps-enligne.fr

Showing 10 out of 277 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IHC, ELISA, WB 25 μL Connectez-vous pour afficher 1 to 2 Days
$139.00
Détails
Humain Souris Inconjugué IHC, ELISA Abeta oligomer-specific antibody was adsorbed to Nunc-Immuno MaxiSorp plates (Nunc, Roskilde, Denmark) at 2 ug/ml in PBS. 1 ml of a 10 uM Aβ(1-42) sample containing a small fraction of Aβ-oligomers was separated using a superdex G75 (10/30) column. Aβ-fractions collected from the SEC were allowed to bind to OMAB plates for 20 minutes at 0°C. All fractions were analyzed and bound Aβ was detected using a polyclonal rabbit anti-Aβ antibody (ABIN249343) at a 1:1000 dilution followed by an anti-rabbit HRP-conjugated secondary antibody at a 1:5000 dilution (GE healthcare). ECBlue (Medicago, Uppsala, Sweden) was used as a substrate for HRP and the signal was detected by measuring the absorbance at 450 nm. Blocking solution and antibody-dilutions were made with 5% Non-fat dry milk in PBST and all washes were performed with PBS containing 0.1% Tween-20 (PBST). 10 µm of coronal sections from fresh-frozen transgenic mouse brain mutant (A) and wild type (B). Post-fixation in 4% formaldehyde solution, 5 min. OMAB antibody diluted 1:500, incubation at 4ºC ON. Mouse on mouse HRP-Polymer kit according to company instructions. Biocare Medical: BC-MM510 (Histolab) DAB substrate kit for peroxidase. Vector Laboratories: SK-4100 (ImmunKemi) Counterstained with Mayers HTX. 50 μg Connectez-vous pour afficher 6 to 8 Days
$766.59
Détails
Poulet Lapin Inconjugué IHC, WB Immunohistochemical analysis of Beta Amyloid (pT743) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Beta Amyloid (pT743) expression in MCF7 colchicine-treated (A), mouse liver (B), PC12 (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$575.00
Détails
Humain Souris Inconjugué ELISA, ICC, IF, IHC, IHC (ff), IHC (p), IP, WB Immunocytochemistry/Immunofluorescence: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - Immunofluorescent detection of beta Amyloid with MOAB-2 in the subiculim of 1-, 2- and 4- month old 5xFAD mice. Scale bar 20 um (from PMID: 22423893). Immunohistochemistry: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - IHC analysis of beta Amyloid on normal mouse brain (left) and 5xFAD mouse brain (right) using DAB with hematoxylin counterstain. The MOAB-2 antibody was used at 1:20 on normal mouse brain and at 1:400 on 5xFAD mouse brain. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$514.63
Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p), WB Immunohistochemistry: beta Amyloid Antibody [NBP2-25093] - Analysis of APP in human brain tissue with APP antibody at 2.5 ug/ml. Immunohistochemistry-Paraffin: beta Amyloid Antibody [NBP2-25093] - Human brain (Alzheimer's disease) tissue with APP antibody at 10 ug/mL. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$485.88
Détails
Souris Chèvre Inconjugué ELISA, WB Western Blot: beta Amyloid Antibody [NBP1-97755] - (0.03ug/ml) Analysis of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Connectez-vous pour afficher 7 to 9 Days
$485.88
Détails
Boeuf (Vache) Lapin Inconjugué ELISA, ICC, IF, IHC, Act (ligand), WB Western Blot: beta Amyloid [Pyro Glu3] Antibody [NBP1-44048] - Lane 1-10: beta Amyloid pyro E3 peptide. Load: 1 ug per lane 1-2, 0.2 ug per lane 3-4, 0.05 ug per lane 5-6, 0.01 ug per lane 7-8, 0.005 ug per lane 9-10. Primary antibody: Beta Amyloid pyro E3 antibody at 0.5 ug/mL for overnight at 4C. Secondary antibody: IRDye800 rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4C. Predicted/Observed size: 86.9 kDa for beta Amyloid pyro E3 peptide. Cross reactivity with Beta Amyloid 3 peptide is >1000 fold below pyrE3 reactivity and contains no reactivity towards the Beta Amyloid 42 A beta peptide (data not shown). Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu3] Antibody [NBP1-44048] - Laser scanning confocal microscopy was carried out using human tissue sections from frontal cortex. Figure A shows an example section that was immunostained for the presence of pyrE3Abeta (green). Figure B shows that the immunogen peptide completely blocked the NBP1-44048 antibody. 0.05 mg Connectez-vous pour afficher 7 to 9 Days
$585.06
Détails
Fruit Fly Lapin Inconjugué ELISA, ICC, IF, IHC, Act (ligand), WB Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu11] Antibody [NBP1-44070] - beta-amyloid (pyroglu11) NBP1-44070 in red (left) co-labeled with 6E10 in green (middle) and merge (right). Image from verified customer review. Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu11] Antibody [NBP1-44070] - Laser scanning confocal microscopy was carried out using human tissue sections from frontal cortex. Figure A shows an example section that was immunostained for the presence of pyrE11Abeta (green). Figure B shows that the immunogen peptide completely blocked the NBP1-44070 antibody. 0.05 mg Connectez-vous pour afficher 7 to 9 Days
$585.06
Détails
Humain Lapin Inconjugué EIA, IF, IHC (p), WB 0.1 mg Connectez-vous pour afficher 6 to 8 Days
$533.50
Détails
Humain Lapin Inconjugué ELISA, IF, IHC, WB 100 μL Connectez-vous pour afficher 16 Days
$181.73
Détails

Abeta Anticorps par réactivité, application, clonalité et conjugué

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anti-beta Amyloid Anticorps mieux référencés

  1. Human Monoclonal beta Amyloid Primary Antibody pour ELISA, ICC - ABIN4284085 : Youmans, Tai, Kanekiyo, Stine, Michon, Nwabuisi-Heath, Manelli, Fu, Riordan, Eimer, Binder, Bu, Yu, Hartley, LaDu: Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody. dans Molecular neurodegeneration 2012 (PubMed)
    Show all 8 Pubmed References

  2. Cow (Bovine) Polyclonal beta Amyloid Primary Antibody pour ELISA, ICC - ABIN4284076 : He, Barrow: The A beta 3-pyroglutamyl and 11-pyroglutamyl peptides found in senile plaque have greater beta-sheet forming and aggregation propensities in vitro than full-length A beta. dans Biochemistry 1999 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal beta Amyloid Primary Antibody pour ELISA, IF - ABIN5508784 : Markoutsa, Papadia, Clemente, Flores, Antimisiaris: Anti-Aβ-MAb and dually decorated nanoliposomes: effect of Aβ1-42 peptides on interaction with hCMEC/D3 cells. dans European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012 (PubMed)
    Show all 4 Pubmed References

  4. Human beta Amyloid Primary Antibody pour ELISA (Capture), IF - ABIN1110165 : Levites, Jansen, Smithson, Dakin, Holloway, Das, Golde et al.: Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor ... dans The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 3 Pubmed References

  5. Fruit Fly (Drosophila melanogaster) Polyclonal beta Amyloid Primary Antibody pour ELISA, ICC - ABIN4284077 : Youssef, Florent-Béchard, Malaplate-Armand, Koziel, Bihain, Olivier, Leininger-Muller, Kriem, Oster, Pillot: N-truncated amyloid-beta oligomers induce learning impairment and neuronal apoptosis. dans Neurobiology of aging 2008 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal beta Amyloid Primary Antibody pour ELISA (Capture), IF - ABIN190335 : Levites, Das, Price, Rochette, Kostura, McGowan, Murphy, Golde: Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model. dans The Journal of clinical investigation 2006 (PubMed)
    Show all 2 Pubmed References

  7. Human beta Amyloid Primary Antibody pour IF, IP - ABIN1110164 : Levites, Smithson, Price, Dakin, Yuan, Sierks, Kim, McGowan, Reed, Rosenberry, Das, Golde: Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models. dans FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal beta Amyloid Primary Antibody pour IHC (fro), IHC (p) - ABIN2477631 : Romaguera, Grimalt, Vilaplana: Eczematous and purpuric allergic contact dermatitis from boots. dans Contact dermatitis 1990 (PubMed)
    Show all 3 Pubmed References

  9. All Species Monoclonal beta Amyloid Primary Antibody pour ELISA, WB - ABIN316413 : Irwin, Edward Wong, Kwon: Determining binding sites of polycyclic aromatic small molecule-based amyloid-beta peptide aggregation modulators using sequence-specific antibodies. dans Analytical biochemistry 2014 (PubMed)

Plus d’anticorps contre beta Amyloid partenaires d’interaction

Human Amyloid beta (Abeta) interaction partners

  1. Data suggest that aggregates of amyloid beta(1-40) induce excessive generation of reactive oxygen species, MAPK (Montrer MAPK1 Anticorps)/NFkappaB (Montrer NFKB1 Anticorps) signaling activation, and NLRP3 (Montrer NLRP3 Anticorps) inflammasome activation in retinal pigment epithelial cells mimicking changes seen in age-related macular degeneration; this mechanism is dependent on NADPH oxidase (Montrer NOX1 Anticorps).

  2. These results demonstrate a stage-dependent plasma Abeta (Montrer APP Anticorps) increase that is augmented by loss of glomerulotubular integrity, low body weight, and inflammation, demonstrating a multifaceted role of renal dysfunction in Abeta (Montrer APP Anticorps) retention.

  3. Combining a murine APP (Montrer APP Anticorps)-deficient and a human APP (Montrer APP Anticorps)-transgenic strain, we were able to analyse the progression of the cortical amyloidosis independent of the murine variant. The lack of endogenous mAPP (Montrer XPNPEP2 Anticorps) resulted in accelerated deposition and, thus, increased number of senile plaques and higher levels of aggregated hAbeta.

  4. APP levels then decrease progressively as a function of age in close relationship with the gradual normalization of FMRP and hnRNP C levels.

  5. In Alzheimer's Disease brain, amyloid Beta-protein binds to synapses and requires the expression of amyloid precursor protein (Montrer APP Anticorps) to disrupt synaptic activity.

  6. activation of mTOR (Montrer FRAP1 Anticorps) signalling via RHEB (Montrer RHEB Anticorps) over-expression inhibited the starvation-induced autophagy but did not affect trafficking of tf-Amyloid precursor protein (APP (Montrer APP Anticorps)). These results show tf-APP (Montrer APP Anticorps) can be used to determine how APP (Montrer APP Anticorps) is trafficked through the lysosomal system of the cell.

  7. Study found that FERMT2 (Montrer FERMT2 Anticorps) (a beta3-integrin (Montrer ITGB3 Anticorps) co-activator) was significantly associated with a variation in cerebrospinal fluid Abeta (Montrer APP Anticorps) peptide levels in 2886 Alzheimer's disease cases.Under-expression of FERMT2 (Montrer FERMT2 Anticorps) increases Abeta (Montrer APP Anticorps) peptide production by raising levels of mature APP (Montrer APP Anticorps) at the cell surface and facilitating its recycling

  8. a 99-aa C-terminal fragment of APP (Montrer APP Anticorps),C99, in addition to its localization in endosomes, can also be found in mitochondria-associated endoplasmic reticulum (ER) membranes, where it is normally processed rapidly by gamma-secretase.

  9. Photoinduced electrons of g-C3 N4 generate reactive oxygen resulting in photooxidation of amyloid peptides that blocks Abeta (Montrer APP Anticorps) aggregation.

  10. Studies indicate that amyloid precursor-like protein 2 (APLP2 (Montrer APLP2 Anticorps)) and amyloid precursor protein (APP (Montrer APP Anticorps)) are linked to increased tumor cell proliferation, migration, and invasion.

Mouse (Murine) Amyloid beta (Abeta) interaction partners

  1. This study demonstrates the neuroprotective effect of TSG (Montrer TWSG1 Anticorps) on APP (Montrer APP Anticorps) expression, suggesting that TSG (Montrer TWSG1 Anticorps) may be beneficial for AD prevention and treatment.

  2. SNX15 (Montrer SNX15 Anticorps) regulates the recycling of APP (Montrer APP Anticorps) to cell surface and, thus, its processing for Abeta (Montrer APP Anticorps) generation.

  3. Immunohistochemical analysis confirmed increased amount of NOS1 (Montrer NOS1 Anticorps) protein in neuronal somata and processes in the perilesional cortex in APP (Montrer APP Anticorps)/PS1 (Montrer PSEN1 Anticorps)-severe traumatic brain injury(TBI) mice compared to APP (Montrer APP Anticorps)/PS1 (Montrer PSEN1 Anticorps)-sham (p < 0.05) or Wt-sTBI mice (p < 0.01).

  4. Combining a murine APP (Montrer APP Anticorps)-deficient and a human APP (Montrer APP Anticorps)-transgenic strain, we were able to analyse the progression of the cortical amyloidosis independent of the murine variant. The lack of endogenous mAPP (Montrer XPNPEP2 Anticorps) resulted in accelerated deposition and, thus, increased number of senile plaques and higher levels of aggregated hAbeta.

  5. our findings indicate that sortilin (Montrer SORT1 Anticorps) is a beneficial protein for the reduction of amyloid pathology in APP (Montrer APP Anticorps)/PS1 (Montrer PSEN1 Anticorps) mice by promoting APP (Montrer APP Anticorps) degradation

  6. APP levels then decrease progressively as a function of age in close relationship with the gradual normalization of FMRP and hnRNP C levels.

  7. a 99-aa C-terminal fragment of APP (Montrer APP Anticorps),C99, in addition to its localization in endosomes, can also be found in mitochondria-associated endoplasmic reticulum (ER) membranes, where it is normally processed rapidly by gamma-secretase.

  8. The authors concluded that the FcgammaRIIb-SHIP2 (Montrer INPPL1 Anticorps) axis links Abeta (Montrer APP Anticorps) neurotoxicity to tau pathology by dysregulating phosphoinositide metabolism, providing insight into therapeutic potential against Alzheimer's disease.

  9. results suggest that PrP(C (Montrer PRNP Anticorps)) recognizes structural features common to both Abeta (Montrer APP Anticorps) oligomers and fibril ends and that this interaction could contribute to the neurotoxic effect of Abeta (Montrer APP Anticorps) aggregates.

  10. Our study provides the first direct evidence that Abeta, an AD-linked factor, is associated to the pathogenesis of ALS and provides molecular clues to understand common aggregation mechanisms in the pathogenesis of neurodegenerative diseases.

beta Amyloid (Abeta) profil antigène

Profil protéine

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Gene names and symbols associated with anti-Amyloid beta (Abeta) Anticorps

  • amyloid beta precursor protein (APP) anticorps
  • amyloid beta precursor protein (app) anticorps
  • amyloid beta precursor protein (App) anticorps
  • amyloid beta (A4) precursor protein (App) anticorps
  • aaa anticorps
  • Abeta anticorps
  • Abpp anticorps
  • ad1 anticorps
  • Adap anticorps
  • Ag anticorps
  • appi anticorps
  • betaApp anticorps
  • ctfgamma anticorps
  • Cvap anticorps
  • E030013M08Rik anticorps
  • PN-II anticorps
  • pn2 anticorps

Protein level used designations for anti-Amyloid beta (Abeta) Anticorps

alzheimer disease amyloid protein , amyloid beta A4 protein , beta-amyloid peptide , cerebral vascular amyloid peptide , peptidase nexin-II , preA4 , protease nexin-II , amyloid beta (A4) precursor protein (peptidase nexin-2, Alzheimer disease) , amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) , beta-amyloid precursor protein , alzheimer disease amyloid A4 protein homolog , amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) , ABPP , AG , amyloid A4 , amyloidogenic glycoprotein , appican , protease nexin II

GENE ID SPECIES
351 Homo sapiens
448208 Xenopus (Silurana) tropicalis
100427716 Macaca mulatta
54226 Rattus norvegicus
11820 Mus musculus
Fournisseurs de qualité sélectionnés pour anti-beta Amyloid (Abeta) Anticorps
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