B-Cell Linker (BLNK) Kits ELISA

BLNK encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. De plus, nous expédions B-Cell Linker Anticorps (205) et B-Cell Linker Protéines (15) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
BLNK 17060 Q9QUN3
BLNK 29760 Q8WV28
BLNK 499356 Q4KM52
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Top B-Cell Linker Kits ELISA sur anticorps-enligne.fr

Showing 10 out of 30 products:

Catalogue No. Reactivité Sensibilité Gamme Quantité Fournisseur Livraison Prix Détails
Humain 0.094 ng/mL 0.156-10 ng/mL 96 Tests Connectez-vous pour afficher 10 to 13 Days
600,00 €
Détails
Porc 0.094 ng/mL 0.156-10 ng/mL 96 Tests Connectez-vous pour afficher 10 to 13 Days
666,67 €
Détails
Lapin 37.5 pg/mL 62.5-4000 pg/mL 96 Tests Connectez-vous pour afficher 10 to 13 Days
666,67 €
Détails
Cobaye 0.469 ng/mL 0.781-50 ng/mL 96 Tests Connectez-vous pour afficher 10 to 13 Days
666,67 €
Détails
Poulet 0.094 ng/mL 0.156-10 ng/mL 96 Tests Connectez-vous pour afficher 10 to 13 Days
666,67 €
Détails
Rat 1.0 pg/mL 250-5000 pg/mL 96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
Détails
Singe 1.0 pg/mL 250-5000 pg/mL 96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
Détails
Souris 1.0 pg/mL 250-5000 pg/mL 96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
Détails
Chien 1.0 pg/mL 250-5000 pg/mL 96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
Détails
Humain
96 Tests Connectez-vous pour afficher 6 to 8 Days
553,10 €
Détails

Plus Kits ELISA pour B-Cell Linker partenaires d'interaction

Mouse (Murine) B-Cell Linker (BLNK) interaction partners

  1. The pre-B-cell receptor (pre-BCR (Montrer BCR Kits ELISA)) signaling molecules BLNK, BTK (Montrer BTK Kits ELISA) and BANK1 (Montrer BANK1 Kits ELISA) were positively regulated by the ZFP521 gene, leading to enhancement of the pre-BCR (Montrer BCR Kits ELISA) signaling pathway.

  2. Authors demonstrate leukemogenicity of PAX5 (Montrer PAX5 Kits ELISA)-PML (Montrer PML Kits ELISA) by introducing it into normal mouse pro-B cells; B-cell linker protein (Blnk) is repressed by PAX5 (Montrer PAX5 Kits ELISA)-PML (Montrer PML Kits ELISA) in leukemia cells; enforced expression of Blnk increases survival despite introduction of PAX5 (Montrer PAX5 Kits ELISA)-PML (Montrer PML Kits ELISA).

  3. B-cell linker protein expression contributes to controlling allergic and autoimmune diseases by mediating IL-10 (Montrer IL10 Kits ELISA) production in regulatory B cells.

  4. Tumor suppressor BLNK is a target of transcriptional activation by PU.1 and Spi-B (Montrer SPIB Kits ELISA) in the B cell lineage.

  5. a novel negative feedback regulation of BCR (Montrer BCR Kits ELISA) signaling by HPK1-mediated phosphorylation, ubiquitination, and subsequent degradation of the activated BLNK

  6. CMTM7 (Montrer CMTM7 Kits ELISA) functions to link sIgM and BLNK in the plasma membrane.

  7. Live cell imaging and co-immunoprecipitation experiments confirmed that both SLP65 and CIN85 (Montrer SH3KBP1 Kits ELISA) are both required for the onset and progression phases of B-cell antigen receptor signal transduction.

  8. malignant transformation of Btk (Montrer BTK Kits ELISA)/Slp65 double-deficient pre-B cells is independent of deregulated V(D)J recombination activity.

  9. Swip-1 (Montrer WSB1 Kits ELISA) provides a membrane scaffold that is required for the Syk (Montrer SYK Kits ELISA)-, SLP-65-, and PLCgamma2 (Montrer PLCG2 Kits ELISA)-dependent BCR (Montrer BCR Kits ELISA)-induced calcium flux.

  10. malignant transformation of Slp65(-/-) pre-B cells involves disruption of the p19(Arf)-Mdm2-p53 tumor suppressor pathway

Human B-Cell Linker (BLNK) interaction partners

  1. vesicular signaling scaffolds are required for B cell activation indicates that vesicles may deliver preassembled signaling cargo to sites of BCR (Montrer BCR Kits ELISA) activation.

  2. early Ca(2 (Montrer CA2 Kits ELISA)+) fluxing provides feed-forward signal amplification by promoting anchoring of the PLCgamma2 (Montrer PLCG2 Kits ELISA) C2 domain to phospho-SLP65.

  3. up-regulation of BLNK is associated with RUNX1 (Montrer RUNX1 Kits ELISA) mutations in cytogenetically normal acute myeloid leukemia (Montrer BCL11A Kits ELISA).

  4. Live cell imaging and co-immunoprecipitation experiments confirmed that both SLP65 and CIN85 (Montrer SH3KBP1 Kits ELISA) are both required for the onset and progression phases of B-cell antigen receptor signal transduction.

  5. 16 of the 34 childhood pre-B acute lymphoblastic leukaemia samples that were tested showed a complete loss or drastic reduction of SLP-65 expression

  6. The BLNK protein is present in the majority of mediastinal B cell lymphomas.

  7. In B cells SLP-65 exists in a 180 kDa complex as well as in monomeric form.

  8. V(H) gene rearrangement represents a frequent feature in B-lymphoid malignancy, which can be attributed to SLP65 deficiency in many cases.

  9. Syk (Montrer SYK Kits ELISA) is required to link phosphorylated SLP-65 to Ca(2 (Montrer CA2 Kits ELISA)+) mobilization.

  10. Plasmacytoid dendritic cells express a signalosome consisting of Lyn (Montrer LYN Kits ELISA), Syk (Montrer SYK Kits ELISA), Btk (Montrer BTK Kits ELISA), Slp65 (Blnk) and PLCgamma2 (Montrer PLCG2 Kits ELISA). Triggering CD303 leads to tyrosine phosphorylation of Syk (Montrer SYK Kits ELISA), Slp65, PLCgamma2 (Montrer PLCG2 Kits ELISA) & cytoskeletal proteins.

B-Cell Linker (BLNK) profil antigène

Antigen Summary

This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with B-Cell Linker (BLNK) Kits ELISA

  • B-cell linker (BLNK) anticorps
  • B-cell linker (blnk) anticorps
  • B-cell linker protein (blnk) anticorps
  • B cell linker (Blnk) anticorps
  • B-cell linker (Blnk) anticorps
  • B-cell linker-like (LOC100354716) anticorps
  • AGM4 anticorps
  • BASH anticorps
  • bca anticorps
  • blnk anticorps
  • BLNK-S anticorps
  • Ly-57 anticorps
  • LY57 anticorps
  • Lyw-57 anticorps
  • MGC147045 anticorps
  • SLP-65 anticorps
  • SLP65 anticorps

Protein level used designations for B-Cell Linker (BLNK) Kits ELISA

B-cell linker , B-cell linker protein , b-cell linker protein-like , B-cell adapter containing a SH2 domain protein , B-cell adapter containing a Src homology 2 domain protein , cytoplasmic adapter protein , lymphocyte antigen 57 , src homology 2 domain-containing leukocyte protein of 65 kDa , B cell adaptor containing SH2 domain , B cell linker protein , B-cell activation , Src homology 2 domain-containing leukocyte protein of 65 kDa , Src homology [SH2] domain-containing leukocyte protein of 65 kD , B cell linker protein BLNK , B-cell adapter SH2 domain-containing protein , SLP-65

GENE ID SPECIES
100070841 Equus caballus
405764 Danio rerio
450641 Pan troglodytes
548350 Xenopus (Silurana) tropicalis
704363 Macaca mulatta
100306798 Salmo salar
100456635 Pongo abelii
100481331 Ailuropoda melanoleuca
100593492 Nomascus leucogenys
17060 Mus musculus
29760 Homo sapiens
395733 Gallus gallus
499356 Rattus norvegicus
486814 Canis lupus familiaris
100152350 Sus scrofa
510393 Bos taurus
100712978 Cavia porcellus
101111241 Ovis aries
100354716 Oryctolagus cuniculus
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