anti-BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) Anticorps

BACH1 encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). De plus, nous expédions BACH1 Protéines (5) et BACH1 Kits (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
BACH1 12013 P97302
BACH1 571 O14867
BACH1 304127  
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Top anti-BACH1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 106 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IF, ELISA, WB Western blot analysis of extracts from HepG2 cells, using BACH1 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using BACH1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué WB <b>WB Suggested Anti-BACH1 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Humain Lapin Inconjugué EIA, WB BACH1 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35µg/lane).This demonstrates the BACH1 antibody detected the BACH1 protein (arrow). 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Souris Inconjugué WB BACH1 monoclonal antibody (M02), clone 1B8 Western Blot analysis of BACH1 expression in NIH/3T3. Detection limit for recombinant GST tagged BACH1 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$450.00
Détails
Humain Souris Inconjugué FACS, IHC, IHC (p), WB Immunohistochemistry-Paraffin: BACH1 Antibody (4E11) [NBP2-01904] - Staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-BACH1 mouse monoclonal antibody. Flow Cytometry: BACH1 Antibody (4E11) [NBP2-01904] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-BACH1 antibody, and then analyzed by flow cytometry. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$447.56
Détails
Humain Lapin Inconjugué WB BACH1 Antibody (C-term) (ABIN658569) western blot analysis in ZR-75-1 cell line lysates (35 µg/lane). This demonstrates the BACH1 antibody detected the BACH1 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Lapin Inconjugué IF, IHC (p), WB 0.1 mg Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$493.17
Détails
Humain Souris Inconjugué FACS, IHC, WB HEK293T cells transfected with either RC221628 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-BACH1 antibody (ABIN2455676), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BACH1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-BACH1. 100 μL Connectez-vous pour afficher 2 to 3 Days
$482.90
Détails
Humain Lapin Inconjugué ELISA, IF, IHC, WB 100 μL Connectez-vous pour afficher 16 Days
$175.80
Détails

BACH1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Mouse (Murine)
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Human , , ,
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Rat (Rattus)


anti-BACH1 Anticorps mieux référencés

  1. Human Monoclonal BACH1 Primary Antibody pour ELISA, WB - ABIN560022 : Kanzaki, Shinohara, Itohiya, Yamaguchi, Katsumata, Matsuzawa, Fukaya, Miyamoto, Wada, Nakamura: RANKL induces Bach1 nuclear import and attenuates Nrf2-mediated antioxidant enzymes, thereby augmenting intracellular reactive oxygen species signaling and osteoclastogenesis in mice. dans FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2016 (PubMed)

  2. Human Monoclonal BACH1 Primary Antibody pour FACS, IHC - ABIN4282846 : Cha, Lee, Han, Kim, Kang, Choi, Cho: MicroRNA alteration and putative target genes in high-grade prostatic intraepithelial neoplasia and prostate cancer: STAT3 and ZEB1 are upregulated during prostate carcinogenesis. dans The Prostate 2016 (PubMed)

Plus d’anticorps contre BACH1 partenaires d’interaction

Zebrafish BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) interaction partners

  1. Bach1 regulates the liver specificity and transience of the Nrf2a (Montrer NFE2L2 Anticorps)-dependent induction of hmox1a and that heme mediates this regulation through Bach1 inhibition based on its level in each tissue.

  2. The Bach1b-MafK heterodimer represses the zymogen promoters, whereas the Nrf2a-MafK heterodimer activates them.

Mouse (Murine) BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) interaction partners

  1. Theraputic effects of Pirfenidone for induced pulmonary fibrosis were involved in Nrf2 (Montrer NFE2L2 Anticorps)/Bach1 equilibrium which regulated the capacity of oxidative stress.

  2. Data suggest that Abcb10 (Montrer ABCB10 Anticorps) silencing results in alteration in heme biosynthesis transcriptional profile due to repression by transcriptional regulator Bach1. (Abcb10 (Montrer ABCB10 Anticorps) = ATP-binding cassette, sub-family B [MDR-TAP], member 10; Bach1 = BTB and CNC homology 1, basic leucine zipper transcription factor 1)

  3. This study showed that RANKL (Montrer TNFSF11 Anticorps) favors osteoclastogenesis via attenuation of Nrf2 (Montrer NFE2L2 Anticorps)-mediated antioxidant enzyme expression by competing with Bach1 nuclear accumulation.

  4. this study provides new insight into the function of iron and Bach1 in erythroblast maturation by using efficacious regimens that can induce severe ID.

  5. miR (Montrer MLXIP Anticorps)-196a, which binds to the 3'-untranslated region of the transcriptional repressor BTB and CNC homology 1 (Bach1) and regulates its expression, and subsequently leads to higher levels of lung HO-1 (Montrer HMOX1 Anticorps) mRNA.

  6. Bach1 siRNA exerts protective effects against bleomycin-induced pulmonary fibrosis in mice.

  7. These results suggest that Bach1 and Bach2 (Montrer BACH2 Anticorps) work in a complementary manner to maintain the normal function of the AMs (Montrer MAT1A Anticorps) and surfactant homeostasis in the lung.

  8. By integrating the chromatin immunoprecipitation and next-generation sequencing data with a comparative analysis of gene expression in Bach1-deficient and wild type immortalized mouse embryonic fibroblasts (iMEFs), study found 35 new genes whose expression was repressed by BACH1. Known functions of some of these genes suggested a role of BACH1 in adipocyte differentiation, which was verified using iMEFs.

  9. Bach1 deficiency reduces the severity of osteoarthritis-like changes. This may be due to maintenance of cartilage homeostasis and joint health by antioxidant effects

  10. Bach1 suppresses angiogenesis after ischemic injury and impairs Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) signaling by disrupting the interaction between beta-catenin (Montrer CTNNB1 Anticorps) and TCF4 (Montrer TCF4 Anticorps) and by recruiting histone deacetylase 1 (Montrer HDAC1 Anticorps) to the promoter of TCF4 (Montrer TCF4 Anticorps)-targeted genes.

Human BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) interaction partners

  1. The electrophilic character of quinones ensure their conjugation with Bach1, which is important for the downregulation of Bach1 and the upregulation of Nrf2 (Montrer GABPA Anticorps) signaling.

  2. Our results suggest that the bach1-specific small interfering RNA effectively decrease CXCR4 (Montrer CXCR4 Anticorps) receptor, matrix metalloproteinase-9 (Montrer MMP9 Anticorps) expression and breast adenocarcinoma cells invasive, also increased the expression of tumor-suppressive microRNA-203 and miR (Montrer MLXIP Anticorps)-145

  3. BACH1 down-regulation in HT29 colon cancer cells had no effect on cell growth but did inhibit cell migration by decreasing metastasis-related genes expression.

  4. This study indicates that the expression of BACH1 could be elevated as a compensatory mechanism to decrease the globin chain imbalance as well as to reduce the oxidative stress found in hemoglobin E/beta-thalassemia.

  5. A short while ago some studies suggested that BACH1 is involved in cancers, especially breast cancer. This factor is mentioned as a novel master regulator which adjusts several genes involved in bone metastasis of breast cancer, especially CXCR4 (Montrer CXCR4 Anticorps) and MMP1 (Montrer MMP1 Anticorps), two main genes in the enhancement of cancer cell migration and invasion to distant organs. [Review]

  6. Bach1 suppresses cell proliferation and induces cell-cycle arrest and apoptosis.

  7. Induction of GSH-related genes xCT (Montrer SLC7A11 Anticorps) and GCLM (Montrer GCLM Anticorps) were oxygen and Bach1-insensitive during long-term culture under 5% O2, providing the first evidence that genes related to GSH synthesis mediate protection afforded by Nrf2 (Montrer GABPA Anticorps)-Keap1 (Montrer KEAP1 Anticorps) defense pathway

  8. heme oxygenase-1 (Montrer HMOX1 Anticorps) expression is induced by gold nanoparticles through Nrf2 (Montrer GABPA Anticorps) activation and Bach1 export in human vascular endothelial cells

  9. Cyanidin-3-O-glucoside protects HUVECs from palmitic acid-induced injuryby modulating the balance of Nrf2 (Montrer GABPA Anticorps) versus Bach1 inside the nucleus so influencing upregulation of electrophile responsive element mediated gene expression.

  10. sensitizer-induced up-regulation of both the endogenous HMOX1 (Montrer HMOX1 Anticorps) and the luciferase constructs under the control of the HMOX1 (Montrer HMOX1 Anticorps)-ARE or the full HMOX1 (Montrer HMOX1 Anticorps) promoter appear to be under the control of both Nrf2 (Montrer GABPA Anticorps) and Bach1.

BACH1 profil antigène

Profil protéine

This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene.

Gene names and symbols associated with BACH1

  • BTB domain and CNC homolog 1 (BACH1) anticorps
  • BTB and CNC homology 1, basic leucine zipper transcription factor 1 b (bach1b) anticorps
  • BTB and CNC homology 1, basic leucine zipper transcription factor 1 (bach1) anticorps
  • BTB and CNC homology 1, basic leucine zipper transcription factor 1 (Bach1) anticorps
  • BTB domain and CNC homolog 1 (Bach1) anticorps
  • 6230421P05Rik anticorps
  • AI323795 anticorps
  • BACH-1 anticorps
  • BACH1 anticorps
  • zgc:112205 anticorps

Protein level used designations for BACH1

BTB and CNC homology 1 transcription factor , BTB and CNC homology 1, basic leucine zipper transcription factor 1 , basic leucine zipper transcription factor 1 , transcription regulator protein BACH1-like , BTB and CNC homolog 1 , transcription regulator protein BACH1 , HA2303 , basic region leucine zipper transcriptional regulator BACH1

GENE ID SPECIES
418488 Gallus gallus
487718 Canis lupus familiaris
531350 Bos taurus
100523514 Sus scrofa
553688 Danio rerio
705817 Macaca mulatta
745234 Pan troglodytes
100053654 Equus caballus
100125783 Xenopus (Silurana) tropicalis
100353797 Oryctolagus cuniculus
100385069 Callithrix jacchus
100448413 Pongo abelii
100464674 Ailuropoda melanoleuca
100549402 Meleagris gallopavo
100595281 Nomascus leucogenys
12013 Mus musculus
571 Homo sapiens
304127 Rattus norvegicus
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