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anti-Baculoviral IAP Repeat-Containing 6 (BIRC6) Anticorps

BIRC6 encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. De plus, nous expédions Baculoviral IAP Repeat-Containing 6 Kits (5) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
BIRC6 57448 Q9NR09
BIRC6 12211 O88738
BIRC6 313876  
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Top anti-Baculoviral IAP Repeat-Containing 6 Anticorps sur anticorps-enligne.fr

Showing 10 out of 66 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué EIA, IHC (p) Immunohistochemistry of BRUCE in human small intestine tissue with BIR... 0.1 mg Connectez-vous pour afficher 8 to 10 Days
357,50 €
Détails
Chien Souris Inconjugué IF, WB Western blot analysis of BRUCE on a SW-13 cell lysate (Human adrenal g... Immunofluorescence staining of HeLa cells (Human cervical epitheloid c... 50 μg Connectez-vous pour afficher 2 to 4 Days
195,64 €
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 3 to 4 Days
249,70 €
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), IP, IHC, PLA, WB Detection of Human BIRC6/Apollon by Western Blot and Immunoprecipitati... 0.1 mL Connectez-vous pour afficher 6 to 8 Days
484,00 €
Détails
Humain Chèvre Inconjugué IHC (p), ELISA 50 μg Connectez-vous pour afficher 11 to 14 Days
501,70 €
Détails
Humain Chèvre Inconjugué ELISA, WB   0.1 mg Connectez-vous pour afficher 6 to 8 Days
459,65 €
Détails
Humain Lapin Inconjugué IHC (p) Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 11 to 14 Days
501,70 €
Détails
Humain Lapin Inconjugué IF (p), IHC (p) Formalin-fixed and paraffin embedded human esophageal carcinoma labele... 100 μL Connectez-vous pour afficher 5 to 7 Days
277,90 €
Détails
Humain Lapin Alkaline Phosphatase (AP) IHC, ELISA   200 μL Connectez-vous pour afficher 11 to 14 Days
1.150,64 €
Détails
Humain Lapin Alexa Fluor 594 IF (p)   100 μL Connectez-vous pour afficher 14 to 17 Days
366,11 €
Détails

BIRC6 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité
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anti-Baculoviral IAP Repeat-Containing 6 Anticorps mieux référencés

  1. Human Polyclonal BIRC6 Primary Antibody pour EIA, IHC (p) - ABIN1450019 : Schimmer: Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice. dans Cancer research 2004 (PubMed)

  2. Human Polyclonal BIRC6 Primary Antibody pour ELISA, WB - ABIN184895 : Chen, Naito, Hori, Mashima, Yamori, Tsuruo: A human IAP-family gene, apollon, expressed in human brain cancer cells. dans Biochemical and biophysical research communications 1999 (PubMed)

  3. Dog (Canine) Monoclonal BIRC6 Primary Antibody pour IF, WB - ABIN968408 : Hauser, Bardroff, Pyrowolakis, Jentsch: A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors. dans The Journal of cell biology 1998 (PubMed)

Plus d’anticorps contre Baculoviral IAP Repeat-Containing 6 partenaires d’interaction

Human Baculoviral IAP Repeat-Containing 6 (BIRC6) interaction partners

  1. Results show that in addition to the scaffolding function in complex formation, BRUCE has an E3 ligase function to promote BRIT1 (Montrer MCPH1 Anticorps) deubiquitination by USP8 (Montrer USP8 Anticorps) leading to accumulation of BRIT1 (Montrer MCPH1 Anticorps) at DNA double-strand break.

  2. BIRC6 overexpression is a predictor of poor prognosis in colorectal cancer and could be a potential target for colorectal cancer therapy.

  3. The study demonstrates that the T allele of the rs2754511 in the BIRC6 gene plays a protective role in pseudoexfoliative glaucoma patients of the Pakistani population.

  4. Humanin signaling pathway via htHNR/JAKs/STAT3 (Montrer STAT3 Anticorps) increased the expression levels of mRNA and protein of Apollon/Bruce, an unusual member of the inhibitors of apoptosis proteins

  5. BRUCE acts as a scaffold, bridging the ubiquitin-specific peptidase 8 (USP8 (Montrer USP8 Anticorps)) and BRIT1 (Montrer MCPH1 Anticorps) in a complex to coordinate USP8 (Montrer USP8 Anticorps)-catalyzed deubiquitination of BRIT1 (Montrer MCPH1 Anticorps).

  6. findings demonstrate that BIRC6 overexpression in hepatocellular carcinoma specimens is indicative of poor prognosis and that its interaction with p53 (Montrer TP53 Anticorps) facilitates the degradation of p53 (Montrer TP53 Anticorps)

  7. The expression of BIRC6 in the cytoplasm is associated with epithelial ovarian cancer (EOC) differentiation and may be a novel predictor for poor prognosis of EOC patients after curative resection.

  8. APPOLON to be a novel regulator of mitotic CYCLIN A (Montrer CCNA2 Anticorps) degradation independent of SAC (Montrer ADCY10 Anticorps).

  9. Elevated expression of BIRC6 protein in non-small-cell lung cancers is associated with cancer recurrence and chemoresistance.

  10. Knockdown experiments were performed using BIRC6 lentiviral shRNA and phenotype responses were analyzed by Western blot and MTT-assays.Upon silencing of BIRC6 by shRNA, DIABLO protein levels increased and cells went into apoptosis.

Cow (Bovine) Baculoviral IAP Repeat-Containing 6 (BIRC6) interaction partners

  1. The results of this study reveal the importance of BIRC6 expression for embryo survival during bovine preimplantation embryo development.

Mouse (Murine) Baculoviral IAP Repeat-Containing 6 (BIRC6) interaction partners

  1. Humanin signaling pathway via htHNR/JAKs/STAT3 (Montrer STAT3 Anticorps) increased the expression levels of mRNA and protein of Apollon/Bruce, an unusual member of the inhibitors of apoptosis proteins

  2. BRUCE acts as a scaffold, bridging the ubiquitin-specific peptidase 8 (USP8 (Montrer USP8 Anticorps)) and BRIT1 (Montrer MCPH1 Anticorps) in a complex to coordinate USP8 (Montrer USP8 Anticorps)-catalyzed deubiquitination of BRIT1 (Montrer MCPH1 Anticorps).

  3. BRUCE protects cells against apoptosis and functions as an inhibitor of apoptosis.

  4. BRUCE is broadly expressed in embryonic, extraembryonic, and adult mouse tissues, this bifunctional protein might play a unique role in normal trophoblast differentiation and embryonic survival

  5. p53 (Montrer TP53 Anticorps) is a downstream effector of Bruce, and, in response to loss of Bruce function, p53 (Montrer TP53 Anticorps) activates Pidd (Montrer PIDD Anticorps)/caspase-2 (Montrer CASP2 Anticorps) and Bax (Montrer BAX Anticorps)/Bak (Montrer BAK1 Anticorps), leading to mitochondrial apoptosis

  6. Birc6 plays a role in cell division

  7. These results establish a previously unrecognized link between NFAT (Montrer NFATC1 Anticorps) signaling and regulation of IAP (Montrer ALPI Anticorps) expression and are the first to identify a signaling pathway that increases BRUCE expression.

Baculoviral IAP Repeat-Containing 6 (BIRC6) profil antigène

Profil protéine

This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination.

Gene names and symbols associated with BIRC6

  • baculoviral IAP repeat containing 6 (BIRC6) anticorps
  • baculoviral IAP repeat-containing 6 (BIRC6) anticorps
  • baculoviral IAP repeat-containing 6 (birc6) anticorps
  • baculoviral IAP repeat containing 6 (birc6) anticorps
  • baculoviral IAP repeat-containing 6 (Birc6) anticorps
  • A430032G04Rik anticorps
  • A430040A19Rik anticorps
  • AA501170 anticorps
  • APOLLON anticorps
  • BIRC6 anticorps
  • Bruce anticorps
  • D630005A10Rik anticorps
  • mKIAA1289 anticorps

Protein level used designations for BIRC6

baculoviral IAP repeat-containing 6 (apollon) , baculoviral IAP repeat-containing 6 , BIR repeat-containing ubiquitin-conjugating enzyme , baculoviral IAP repeat-containing protein 6 , ubiquitin-conjugating BIR domain enzyme apollon , ubiquitin-conjugating BIR-domain enzyme apollon , apollon , baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjugating enzyme , baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjugating enzyme; accccbaculoviral IAP repeat-containing 6

GENE ID SPECIES
421463 Gallus gallus
475718 Canis lupus familiaris
709443 Macaca mulatta
720431 Macaca mulatta
796547 Danio rerio
100027051 Monodelphis domestica
100070568 Equus caballus
100079899 Ornithorhynchus anatinus
100135722 Xenopus (Silurana) tropicalis
100225419 Taeniopygia guttata
100342432 Oryctolagus cuniculus
100448259 Pongo abelii
100484115 Ailuropoda melanoleuca
57448 Homo sapiens
534211 Bos taurus
12211 Mus musculus
313876 Rattus norvegicus
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