anti-Bicaudal C Homolog 1 (Drosophila) (BICC1) Anticorps

BICC1 encodes an RNA-binding protein that is active in regulating gene expression by modulating protein translation during embryonic development. De plus, nous expédions BICC1 Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
BICC1 80114 Q9H694
BICC1 83675 Q99MQ1
BICC1 361832  
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Top anti-BICC1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 52 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of BICC1 Antibody (N-term) (ABIN390954) in HL-60 cell line lysates (35 µg/lane). BICC1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with BICC1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Lapin Inconjugué WB 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Lapin Inconjugué EIA, WB   0.4 mL Connectez-vous pour afficher 8 to 11 Days
357,50 €
Détails
Humain Lapin Inconjugué IHC, WB 100 μL Connectez-vous pour afficher 6 to 8 Days
337,56 €
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 3 to 4 Days
349,82 €
Détails
Humain Chèvre Inconjugué ELISA   0.1 mg Connectez-vous pour afficher 6 to 8 Days
472,74 €
Détails
Roussette (Chauve-souris) Chèvre Inconjugué ELISA   100 μg Connectez-vous pour afficher 11 to 14 Days
600,64 €
Détails
Roussette (Chauve-souris) Chèvre Inconjugué ELISA   100 μg Connectez-vous pour afficher 11 to 14 Days
722,86 €
Détails
Chien Chèvre Inconjugué EIA, IP   0.1 mg Connectez-vous pour afficher 8 to 11 Days
357,50 €
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: BICC1 Antibody [NBP1-94171] - Staining of human cell line U-251 MG shows positivity in nucleus but not nucleoli. Immunohistochemistry: BICC1 Antibody [NBP1-94171] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules and cells in glomeruli. 0.1 mL Connectez-vous pour afficher 6 to 9 Days
418,75 €
Détails

BICC1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human , ,
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Mouse (Murine) ,


Rat (Rattus) , ,


anti-BICC1 Anticorps mieux référencés

  1. Human Polyclonal BICC1 Primary Antibody pour WB - ABIN1944768 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... dans Nature genetics 2003 (PubMed)
    Show all 3 references for 1944768

  2. Human Polyclonal BICC1 Primary Antibody pour IHC (p), WB - ABIN390954 : Grupe, Li, Rowland, Nowotny, Hinrichs, Smemo, Kauwe, Maxwell, Cherny, Doil, Tacey, van Luchene, Myers, Wavrant-De Vrièze, Kaleem, Hollingworth, Jehu, Foy, Archer, Hamilton, Holmans, Morris, Catanese et al.: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. ... dans American journal of human genetics 2005 (PubMed)
    Show all 2 references for 390954

Plus d’anticorps contre BICC1 partenaires d’interaction

Zebrafish Bicaudal C Homolog 1 (Drosophila) (BICC1) interaction partners

  1. These results demonstrate that the function of Bicc1 in the kidney is evolutionarily conserved, thus supporting the use of zebrafish as an alternative in vivo model to study the role of mammalian Bicc1 in renal cyst formation.

Human Bicaudal C Homolog 1 (Drosophila) (BICC1) interaction partners

  1. Suggest allelic changes in the regulation of the BICC1 gene in amygdala neurones may contribute to mood disorders.

  2. Results provide some support for the involvement of BICC1 and PCLO (Montrer PCLO Anticorps) in late-life depressive disorders and preliminary evidence that these genetic variants may also influence brain structural volumes

  3. findings identify a role for increased levels of BICC1 in the pathophysiology of depressive behavior

  4. Polymorphisms in intron 2 of BICC1 are associated with its expression and bone (Montrer BEST1 Anticorps) mineral density (BMD)

  5. The minor T-allele of BICC1 has a protective role against major depressive disorder and its known structural and functional brain changes.

  6. The nonsense mutation identified in BICC1 and associated with cystic renal dysplasia results in a complete loss of Wnt (Montrer WNT2 Anticorps) inhibitory activity. The point mutation in the SAM (Montrer TTN Anticorps) domain results in a 22% loss of activity.

Mouse (Murine) Bicaudal C Homolog 1 (Drosophila) (BICC1) interaction partners

  1. Polymerization is a novel disease-relevant mechanism both to stabilize Bicc1 and to present associated mRNAs in specific silencing platforms.

  2. discovered that loss of the Pkd1 (Montrer PKD1 Anticorps) gene product, polycystin-1 (PC1 (Montrer PKD1 Anticorps)), whose mutation causes human autosomal dominant polycystic kidney disease (ADPKD), downregulates Bicc1 expression in vitro and in vivo

  3. Bicc1 is a novel regulator of osteoblastogenesis and bone mineral density (BMD (Montrer BEST1 Anticorps))

  4. Bicc1 KH domains bind the 3' UTRs of AC6 (Montrer ADCY6 Anticorps) and PKIa (Montrer PKIA Anticorps) mRNAs and cognate miRNA precursors, whereas the SAM (Montrer TTN Anticorps) domain loads a silencing complex with AGO2 (Montrer EIF2C2 Anticorps). AC6 (Montrer ADCY6 Anticorps) and PKIa (Montrer PKIA Anticorps) protein levels increase in cystic Bicc1-/- mouse kidneys.

  5. lack of Bicc1 leads to disruption of normal cell-cell junctions.

  6. Data suggest that Bicc1 functions by modulating the expression of polycystin 2 (Pkd2 (Montrer PKD2 Anticorps) by antagonizing the repressive activity of the miR-17 microRNA family on the 3'UTR (Montrer UTS2R Anticorps) of Pkd2 (Montrer PKD2 Anticorps) mRNA.

  7. Binds homoribopolymers in vitro; the third K homology domain is necessary and sufficient for in vitro Bicc1 RNA binding.

  8. Bicc1 and SamCystin (Montrer ANKS6 Anticorps) interact at the protein level suggesting that they function in a common molecular pathway that when perturbed, is involved in cystogenesis.

  9. Data report that targeted inactivation of BicC randomizes left-right asymmetry by disrupting the planar alignment of motile cilia required for cilia-driven fluid flow, and that BicC can uncouple Dvl2 (Montrer DVL2 Anticorps) signaling from the canonical Wnt (Montrer WNT2 Anticorps) pathway.

BICC1 profil antigène

Profil protéine

This gene encodes an RNA-binding protein that is active in regulating gene expression by modulating protein translation during embryonic development. Mouse studies identified the corresponding protein to be under strict control during cell differentiation and to be a maternally provided gene product.

Gene names and symbols associated with BICC1

  • bicaudal C homolog 1 (Drosophila) (BICC1) anticorps
  • bicaudal C homolog 1b (Drosophila) (bicc1b) anticorps
  • bicaudal C homolog 1 (bicc1) anticorps
  • bicaudal C homolog 1 (Drosophila) (Bicc1) anticorps
  • Bic-C anticorps
  • Bicaudal-C anticorps
  • BICC anticorps
  • bicc1 anticorps
  • bpk anticorps
  • CYSRD anticorps
  • jcpk anticorps
  • x-Bic-C anticorps
  • xBic-C anticorps

Protein level used designations for BICC1

bicaudal C homolog 1 (Drosophila) , bicaudal C homolog 1-like , bicaudal C homolog 1 , protein bicaudal C homolog 1-like , bic-C , protein bicaudal C homolog 1 , juvenile congenital polycystic kidney disease , polycystic kidney mutation of BALB/c origin

GENE ID SPECIES
423604 Gallus gallus
450473 Pan troglodytes
537799 Bos taurus
571411 Danio rerio
733856 Xenopus (Silurana) tropicalis
701228 Macaca mulatta
100013824 Monodelphis domestica
100072191 Equus caballus
100412529 Callithrix jacchus
100466363 Ailuropoda melanoleuca
100589900 Nomascus leucogenys
80114 Homo sapiens
608626 Canis lupus familiaris
83675 Mus musculus
361832 Rattus norvegicus
100154253 Sus scrofa
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