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This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. De plus, nous expédions FLASH Kits (7) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 49 products:
Cow (Bovine) Polyclonal FLASH Primary Antibody pour WB - ABIN2784233
Lee, Pi, Lee: Buffer optimization for high resolution of human lung cancer tissue proteins by two-dimensional gel electrophoresis. dans Biotechnology letters 2008
Show all 2 references for ABIN2784233
Human Polyclonal FLASH Primary Antibody pour ICC, IF - ABIN4312087
Chen, Evans, Evans: FLASH knockdown sensitizes cells to Fas-mediated apoptosis via down-regulation of the anti-apoptotic proteins, MCL-1 and Cflip short. dans PLoS ONE 2012
Human Polyclonal FLASH Primary Antibody pour EIA, IF - ABIN499842
Imai, Kimura, Murakami, Yajima, Sakamaki, Yonehara: The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis. dans Nature 1999
Our results indicate that the APAF1 (Montrer APAF1 Anticorps), BAX (Montrer BAX Anticorps), and FLASH genes not only harbor frameshift mutations but also demonstrate mutational ITH, which together might play a role in the tumorigenesis of CRC (Montrer CALR Anticorps) with MSI (Montrer MSI1 Anticorps)-H by affecting the apoptosis of cancer cells.
High-quality solution NMR structures of three homeodomains from human proteins ALX4 (Montrer ALX4 Anticorps), ZHX1 (Montrer ZHX1 Anticorps) and CASP8AP2 were solved.
the predictive values regarding low expressions of H2AFZ (Montrer H2AFZ Anticorps) and CASP8AP2 and high white blood cell count suggest that these features could help to identify more accurately patients at greater risk of relapse.
ARS2 (Montrer SRRT Anticorps) and CASP8AP2 expressions can precisely predict high-risk of relapse and ALL prognosis.
The conserved C-terminal domain shared by FLASH, YARP, and Mute recognizes the C-terminal sequence of NPAT (Montrer NPAT Anticorps) orthologues, thus acting as a signal targeting proteins to histone locus bodies.
Data suggest that SUMO targets FLASH for proteasome-dependent degradation, which is associated with recruitment of FLASH to PML (Montrer PML Anticorps) bodies.
Hypermethylation of two CpG sites upstream of CASP8AP2 promoter influences gene expression and treatment outcome in childhood acute lymphoblastic leukemia.
FLASH/Lsm11 (Montrer LSM11 Anticorps) complex bind a unique combination of polyadenylation factors
These data demonstrate that methylation within the Casp8AP2 promoter correlates with the development of drug resistance and might serve as a biomarker and treatment target for drug resistance in cancer cells.
FLASH knockdown in HT1080 (Montrer CDC123 Anticorps) mutant cells defective in p53 (Montrer TP53 Anticorps) did not significantly accelerate Fas (Montrer FAS Anticorps) mediated apoptosis indicating that the effect was dependent on functional p53 (Montrer TP53 Anticorps).
the functional interaction of E2A (Montrer TCF3 Anticorps) and FLASH play an important role in cell proliferation and cellular senescence via regulation of p21 (Montrer D4S234E Anticorps) expression in experimental glomerulonephritis.
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
CASP8 associated protein 2
, caspase 8 associated protein 2
, CASP8-associated protein 2-like
, CASP8-associated protein 2
, FLASH homolog RIP25
, FLICE associated huge
, FLICE-associated huge protein
, human FLASH