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The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. De plus, nous expédions CEBPA Kits (30) et CEBPA Protéines (11) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 152 products:
Human Polyclonal CEBPA Primary Antibody pour EIA, FACS - ABIN951460
Twu, Hsieh, Lin, Tzeng, Sun, Yu: Phosphorylation status of transcription factor C/EBPalpha determines cell-surface poly-LacNAc branching (I antigen) formation in erythropoiesis and granulopoiesis. dans Blood 2010
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Human Monoclonal CEBPA Primary Antibody pour FACS, ICC - ABIN269606
Ferrari-Amorotti, Keeshan, Zattoni, Guerzoni, Iotti, Cattelani, Donato, Calabretta: Leukemogenesis induced by wild-type and STI571-resistant BCR/ABL is potently suppressed by C/EBPalpha. dans Blood 2006
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Chicken Polyclonal CEBPA Primary Antibody pour IHC, WB - ABIN2787465
Singh, Trivedi, Behre: C/EBPalpha S248A mutation reduces granulocytic differentiation in human leukemic K562 cells. dans Biochemical and biophysical research communications 2008
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Human Polyclonal CEBPA Primary Antibody pour FACS, WB - ABIN653431
Nanri, Uike, Kawakita, Iwanaga, Mitsuya, Asou: A family harboring a germ-line N-terminal C/EBPalpha mutation and development of acute myeloid leukemia with an additional somatic C-terminal C/EBPalpha mutation. dans Genes, chromosomes & cancer 2010
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Human Monoclonal CEBPA Primary Antibody pour FACS, ELISA - ABIN969507
Geest, Buitenhuis, Vellenga, Coffer: Ectopic expression of C/EBPalpha and ID1 is sufficient to restore defective neutrophil development in low-risk myelodysplasia. dans Haematologica 2009
Human Monoclonal CEBPA Primary Antibody pour ICC, FACS - ABIN969048
Jin, Zhang, Yan, Liu, Wang, Ge, Zhai: C/EBPalpha regulates SIRT1 expression during adipogenesis. dans Cell research 2010
Cow (Bovine) Polyclonal CEBPA Primary Antibody pour WB - ABIN2792649
Zhu, Qian, Levy: CCAAT/enhancer-binding protein alpha (C/EBPalpha) activates transcription of the human microsomal epoxide hydrolase gene (EPHX1) through the interaction with DNA-bound NF-Y. dans The Journal of biological chemistry 2004
results demonstrate that the low-level expression of human ACAT2 gene with specific CpG-hypomethylated promoter is regulated by the C/EBP transcription factors in monocytic cells, and imply that the lowly expressed ACAT2 catalyzes the synthesis of certain CE/SE that are assembled into lipoproteins for the secretion
Our study highlighted two novel promoter KLF1 and 3'-region C/EBPalpha motifs in the phenylalanine hydroxylase (PAH) gene which decrease transcription in vitro and, thus, could be considered as PAH expression modifiers.
The QA repeat domain of TCERG1 (Montrer TCERG1 Anticorps) is required for relocalization of CEBPalpha.
In the CCAAT/enhancer binding protein alpha gene, no mutations were detected but a known polymorphism (c.584_589dup ACCCGC) was observed in 26 (28.3%) patients.
The p53 (Montrer TP53 Anticorps)-KLF4 (Montrer KLF4 Anticorps)-CEBPA axis is deregulated in AML (Montrer RUNX1 Anticorps) but can be functionally restored by conventional chemotherapy and novel p53 (Montrer TP53 Anticorps) activating treatments.
C/EBPalpha inhibited breast cancer cell growth via a novel miR (Montrer MLXIP Anticorps)-134/CREB (Montrer CREB1 Anticorps) signaling pathway.
C/EBP-alpha was primarily expressed in hepatocytes in normal liver, but its expression decreased significantly in liver fibrosis
The efficient repression of E2F (Montrer E2F1 Anticorps) dependent S-phase genes and the activation of differentiation genes reside in the balanced DNA binding capacity of C/EBP alpha.
we are the first to identify that miR (Montrer MLXIP Anticorps)-381 suppresses C/EBPalpha-dependent Cx43 (Montrer GJA1 Anticorps) expression in breast cancer cells. The miR (Montrer MLXIP Anticorps)-381-C/EBPalpha-Cx43 (Montrer GJA1 Anticorps) axis might be a useful diagnostic and therapeutic target of metastatic breast cancer
results suggested that C/EBPalpha-saRNA successfully inhibited HCC (Montrer FAM126A Anticorps) metastasis by inhibiting EGFR (Montrer EGFR Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) signaling pathway mediated EMT (Montrer ITK Anticorps) in vitro and in vivo
the DNA sequences to which EVI1 (Montrer MECOM Anticorps) binds at +35 and +37 kb and show that mutation of one of these releases Cebpa from EVI1 (Montrer MECOM Anticorps)-induced suppression.
Cebpa enhancers and silencers in a transcriptional model have roles in hematopoietic lineage specification
Data show that CCAAT-enhancer-binding protein-alpha (C/EBPalpha) directly regulates Kruppel-like factor 4 (Klf4 (Montrer KLF4 Anticorps)) expression and increasing the levels of histone demethylase (Montrer MBD2 Anticorps) Lsd1 (Montrer KDM1A Anticorps) and transcription factor Brd4 (Montrer BRD4 Anticorps) in B cell.
The findings demonstrate a critical role for the +37 kb Cebpa enhancer for hematopoietic-specific Cebpa expression, with enhancer deletion leading to impaired myelopoiesis and potentially preleukemic progenitor expansion.
Data indicate that miR (Montrer MLXIP Anticorps)-25 is a novel negative regulator of adipocyte differentiation and it suppressed 3T3-L1 adipogenesis by targeting KLF4 (Montrer KLF4 Anticorps) and C/EBPalpha, which provides novel insights into the molecular mechanism of miRNA-mediated cellular differentiation.
MYB (Montrer MYB Anticorps) and C/EBPalpha activities are inter-dependent in controlling Flt3 (Montrer FLT3 Anticorps) expression to influence lineage commitment of multipotential progenitors.
Data indicate that white adipose tissue from IgE receptor FcR1-deficient Fcer1a (Montrer FCER1A Anticorps)(-/-) mice showed an increased expression of CCAAT-enhancer-binding protein-alpha (C-EBPalpha) and peroxisome proliferator-activated receptor-gamma (PPARgamma (Montrer PPARG Anticorps)).
miR (Montrer MLXIP Anticorps)-223 regulates adipocyte and osteoblast differentiation through a novel C/EBPs/miR (Montrer MLXIP Anticorps)-223/FGFR2 (Montrer FGFR2 Anticorps) regulatory feedback loop.
Data (including data from studies in transgenic/mutant mice) suggest Cebpa (CCAAT-enhancer binding protein alpha) in myeloid cells is down-regulated in type 2 diabetes resulting in poor maturation of Gr-1 (Montrer GSR Anticorps)+ (chemokine receptor (Montrer CCR1 Anticorps)) myeloid cells.
C/ebpalpha plays a role in liver growth regulation via the p53 (Montrer TP53 Anticorps) pathway.
Dnmt1 (Montrer DNMT1 Anticorps) is required for hematopoietic stem and progenitor cells maintenance via cebpa regulation during definitive hematopoiesis in zebrafish
Data suggest that upregulation of 10-formyltetrahydrofolate dehydrogenase (FDH (Montrer ALDH1L1 Anticorps)) involving CEBPalpha helps relieve embryonic oxidative stress induced (Montrer SQSTM1 Anticorps) by ethanol exposure.
Bmi1 (Montrer BMI1 Anticorps) acts immediately downstream of CCAAT enhancer binding protein-alpha to regulate the survival and self-renewal of hematopoietic stem cells and contribute to the erythropoietic dysplasia.
Results provide first evidence that sumoylation of Cebp-alpha (via SUMO1 (Montrer SUMO1 Anticorps), SUMO2 (Montrer SUMO2 Anticorps), and SUMO3 (Montrer SUMO3 Anticorps)) might contribute to cell fate decision of myelo-erythroid progenitor cells in intermediate cell mass during primitive [extramedullary] hematopoiesis.
An evolutionarily conserved PTEN (Montrer PTEN Anticorps)-C/EBPalpha-CTNNA1 (Montrer CTNNA1 Anticorps) axis controls myeloid development and transformation.
a C/EBP recognition sequence in the proximal promoter region of C/EBPalpha is essential for IL-6 (Montrer IL6 Anticorps)-mediated repression
These results suggest that the CEBPA gene is a strong candidate gene that affects carcass traits in Qinchuan cattle.
Expressions of C-EBPalpha and myostatin (Montrer MSTN Anticorps) in muscles were higher in the concentrate-fed group than in the grass hay (Montrer GTF2H5 Anticorps)-fed group.
C/EBPalpha is an essential regulatory factor for perilipin5 transcription and suggest that fasting stimulates perilipin5 transcription through influencing C/EBPalpha expression.
The differential expression of specific CEBPA/B isoforms observed in maturing follicles and CL may contribute to changes in follicular cell differentiation and increasing steroidogenic capacity.
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
CCAAT/enhancer-binding protein alpha
, C/EBP alpha
, CAAT/enhancer-binding protein DNA-binding protein
, CAAT/enhancer-binding protein, DNA-binding protein
, CCAAT/enhancer binding protein, alpha
, c/EBP alpha
, CCAAT/enhancer binding protein alpha