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anti-Cathepsin C (CTSC) Anticorps

The protein encoded by CTSC, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. De plus, nous expédions Cathepsin C Kits (31) et Cathepsin C Protéines (19) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CTSC 1075 P53634
CTSC 13032 P97821
CTSC 25423 P80067
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Top anti-Cathepsin C Anticorps sur anticorps-enligne.fr

Showing 10 out of 84 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from Jurkat cells, treated with etoposide 25uM 1h, using Dipeptidyl-peptidase 1 (heavy chain,Cleaved-Arg394) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails
Humain Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué ELISA, WB 100 μL Connectez-vous pour afficher 13 Days
154,33 €
Détails
Humain Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Boeuf (Vache) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
653,02 €
Détails
Boeuf (Vache) Lapin Biotin DB, EIA, ID, IF, IP, RIA, WB   1 mL Connectez-vous pour afficher 8 to 10 Days
385,00 €
Détails
Humain Chèvre Inconjugué IHC (p), ELISA Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 11 to 14 Days
501,70 €
Détails
Humain Lapin Inconjugué ELISA, WB 100 μL Connectez-vous pour afficher 11 to 14 Days
565,71 €
Détails
Humain Lapin Inconjugué WB Western blot analysis of extracts of various cells, using CTSC antibody. Immunohistochemistry of paraffin-embedded human stomach using CTSC antibody at dilution of 1:100 (x40 lens). 100 μL Connectez-vous pour afficher 12 Days
261,90 €
Détails
Humain Souris Inconjugué IHC (p), ELISA, WB Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Connectez-vous pour afficher 11 to 14 Days
705,40 €
Détails

CTSC Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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Plus d’anticorps contre Cathepsin C partenaires d’interaction

Human Cathepsin C (CTSC) interaction partners

  1. analysis of fluorescent substrates provides a detailed S' specificity study of cathepsin C

  2. Mutation screening of the CTSC gene from the two patients revealed the presence of the same homozygous nonsense mutation in Papillon-Lefevre syndrome and Haim-Munk syndromes. Phenotypic variants of the same rare disease caused by mutations of the cathepsin C (CTSC) gene.

  3. Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.

  4. CTSC was associated with albuminuria in type 2 diabetes patients.

  5. Homozygous mutation 901G>A in exon 7 of CTSC gene is associated with Papillon-Lefevre syndrome.

  6. Results identify a missense mutation in CTSC gene that segregate within a family with Papillon-Lefevre syndrome.

  7. Papillon-Lefevre syndrome cause by homozygous nonsense mutation of cathepsin C gene.

  8. CatC has a role in the selective tuning of innate and adaptive immune responses, relevant to a chronic immune disease, such as atherosclerosis.

  9. cathepsin C in GCF (Montrer GUCY2F Anticorps) does not seem to have an effect on the pathogenesis of periodontal diseases.

  10. The present account of the 148.621 kb homozygous deletion on chromosome 11 is the first report of a mutational mechanism encompassing the whole CTSC gene.

Mouse (Murine) Cathepsin C (CTSC) interaction partners

  1. During the active remyelinating phase, both CysF knockdown (CysFKD) and microglial-selective CatC overexpression (CatCOE) showed a worsening of the demyelination in Plp (Montrer C3 Anticorps)(4e/-) transgenic mice. Conversely, during the chronic demyelinating phase, CatC knockdown (CatCKD) ameliorated the demyelination. Our results suggest that the balance between CatC and CysF expression controls the demyelination and remyelination process.

  2. Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.

  3. Double immunofluorescence analysis showed that CTLA-2alpha was co-localized with cathepsin L (Montrer CTSL1 Anticorps), cathepsin C, and TINAGL1 (Montrer TINAGL1 Anticorps) in placenta.

  4. CatC has a role in the selective tuning of innate and adaptive immune responses, relevant to a chronic immune disease, such as atherosclerosis.

  5. Data indicate that all-trans retinoic acid (ATRA), which induces miR (Montrer MLXIP Anticorps)-23a expression, decreases cathepsin C (CTSC) expression and granzyme B (Montrer Gzmb Anticorps) activity leading to impaired NK cell cytotoxicity.

  6. These results establish that DPPI is a major determinant of survival following Klebsiella pneumoniae lung infection and suggest that the survival disadvantage in DPPI(+/+) mice is in part due to processing of surfactant protein D (Montrer SFTPD Anticorps) by DPPI.

  7. found no significant role for CtsC during mammary carcinogenesis but revealed squamous carcinogenesis to be functionally dependent on CtsC

  8. Late stage cathepsin C, CXCL13 (Montrer CXCL13 Anticorps) and Ki-67 (Montrer MKI67 Anticorps) overexpression correlate with regional neuropathology in a bovine spongiform encephalopathy transgenic murine model.

  9. Proinflammatory cytokines induce expression and release of cathepsin C in microglial cells during neuroinflammatory progression.

  10. The production of IL-1beta (Montrer IL1B Anticorps) by macrophages, neutrophils, and mast cells in vitro is dependent on caspase-1 (Montrer CASP1 Anticorps) but not on cathepsin C.

Cathepsin C (CTSC) profil antigène

Profil protéine

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Cathepsin C (CTSC) Anticorps

  • cathepsin C (ctsc) anticorps
  • cathepsin C (CTSC) anticorps
  • cathepsin C (TP03_0357) anticorps
  • cathepsin C (CMU_003360) anticorps
  • cathepsin C (TGME49_089620) anticorps
  • cathepsin C (NAEGRDRAFT_80477) anticorps
  • cathepsin C (NAEGRDRAFT_37577) anticorps
  • cathepsin C (Ctsc) anticorps
  • cathepsin C (LOC100101594) anticorps
  • cathepsin C (Smp_183330) anticorps
  • cathepsin J (Ctsj) anticorps
  • AI047818 anticorps
  • CATC anticorps
  • CATP anticorps
  • CatRLP anticorps
  • CPPI anticorps
  • Ctsp anticorps
  • DPP-I anticorps
  • DPP1 anticorps
  • DPPI anticorps
  • HMS anticorps
  • JP anticorps
  • JPD anticorps
  • MGC69126 anticorps
  • MGC107782 anticorps
  • PALS anticorps
  • PDON1 anticorps
  • PLS anticorps

Protein level used designations for anti-Cathepsin C (CTSC) Anticorps

cathepsin C , dipeptidyl peptidase 1 , dipeptidyl peptidase 1 isoform a preproprotein , DPPI , DPP-I , cathepsin J , Dipeptidyl-peptidase 1 , dipeptidyl peptidase I , dipeptidyl transferase , dipeptidyl-peptidase I , dipeptidyl-peptidase 1 , dipeptidylpeptidase 1 , Cat P , cathepsin L-related protein , cathepsin P , catlrp-p , gene/Cathepsin L-related protein

GENE ID SPECIES
380203 Xenopus laevis
407938 Xenopus (Silurana) tropicalis
451469 Pan troglodytes
705320 Macaca mulatta
3500364 Theileria parva strain Muguga
6997925 Cryptosporidium muris RN66
7899372 Toxoplasma gondii ME49
8851692 Naegleria gruberi strain NEG-M
8855504 Naegleria gruberi strain NEG-M
100172530 Pongo abelii
352958 Bos taurus
1075 Homo sapiens
13032 Mus musculus
25423 Rattus norvegicus
100101594 Oryctolagus cuniculus
100714387 Cavia porcellus
403458 Canis lupus familiaris
419014 Gallus gallus
101112686 Ovis aries
8346758 Schistosoma mansoni
26898 Mus musculus
29174 Rattus norvegicus
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