anti-Cdk5 and Abl Enzyme Substrate 1 (CABLES1) Anticorps

CABLES1 encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. De plus, nous expédions Cdk5 and Abl Enzyme Substrate 1 Protéines (4) et Cdk5 and Abl Enzyme Substrate 1 Kits (2) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CABLES1 91768 Q8TDN4
CABLES1 63955 Q9ESJ1
CABLES1 307585  
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Top anti-Cdk5 and Abl Enzyme Substrate 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 26 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from LOVO cells, using Ik3-1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-CABLES1 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué IF, IHC (p), WB 0.1 mg Connectez-vous pour afficher 8 to 10 Days
385,00 €
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué ELISA, IF, IHC, WB 100 μL Connectez-vous pour afficher 13 Days
154,33 €
Détails
Humain Lapin Inconjugué IC, IF, IHC, WB Immunofluorescent analysis of CABLES1 staining in SHSY5Y cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of CABLES1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Connectez-vous pour afficher 11 to 13 Days
464,29 €
Détails
Humain Lapin Inconjugué WB Western blot analysis of extract of various cells, using CABLES1 antibody. 100 μL Connectez-vous pour afficher 12 Days
261,90 €
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), IHC, WB Western Blot: CABLES1 Antibody [ABIN4083003] - Western blot (WB) analysis of CABLES1 (K588) antibody in extracts from LOVO cells. 0.1 mL Connectez-vous pour afficher 3 to 5 Days
426,25 €
Détails
Humain Lapin Inconjugué ELISA, WB 100 μL Connectez-vous pour afficher 11 to 14 Days
565,71 €
Détails
Humain Lapin Inconjugué ICC, IF, WB Western Blot: CABLES1 Antibody  - Western blot analysis in human cell line RT-4 and human cell line U-251 MG. Immunocytochemistry/Immunofluorescence: CABLES1 Antibody  - Staining of human cell line U-2 OS shows localization to nuclear speckles. 100 μL Connectez-vous pour afficher 6 to 9 Days
418,75 €
Détails

CABLES1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité
Human ,
,

Mouse (Murine) ,


Rat (Rattus) ,


anti-Cdk5 and Abl Enzyme Substrate 1 Anticorps mieux référencés

  1. Human Polyclonal CABLES1 Primary Antibody pour ELISA, WB - ABIN1534279 : Nusbaum, Zody, Borowsky, Kamal, Kodira, Taylor, Whittaker, Chang, Cuomo, Dewar, FitzGerald, Yang, Abouelleil, Allen, Anderson, Bloom, Bugalter, Butler, Cook, DeCaprio, Engels, Garber, Gnirke, Hafez et al.: DNA sequence and analysis of human chromosome 18. ... dans Nature 2005 (PubMed)

Plus d’anticorps contre Cdk5 and Abl Enzyme Substrate 1 partenaires d’interaction

Zebrafish Cdk5 and Abl Enzyme Substrate 1 (CABLES1) interaction partners

  1. cables1 is important for neural differentiation during embryogenesis, in a mechanism that likely involves interactions with the Cdk5 (Montrer CDK5 Anticorps)/p35 (Montrer CDK5R1 Anticorps) kinase pathway.

Human Cdk5 and Abl Enzyme Substrate 1 (CABLES1) interaction partners

  1. Cables1/p21 (Montrer CDKN1A Anticorps) pathway has a strong effect on the induction of cell senescence and inhibition of cell growth, and acts as a novel regulatory mechanism in which p21 (Montrer CDKN1A Anticorps) is probably one of several downstream effector molecules to mediate Cables1.

  2. CABLES1 is a critical regulator of corticotrope proliferation that defines a pathway often inactivated in Cushing disease

  3. the results suggest Cables1 as a novel p21 (Montrer CDKN1A Anticorps) regulator through maintaining p21 (Montrer CDKN1A Anticorps) stability and support the model that the tumor-suppressive function of Cables1 occurs at least in part through enhancing the tumor-suppressive activity of p21 (Montrer CDKN1A Anticorps).

  4. Results illuminated a dynamic regulatory system through which activated Akt (Montrer AKT1 Anticorps) and 14-3-3 (Montrer YWHAQ Anticorps) work directly together to neutralize a potent tumor suppressor function of Cables1.

  5. The results did not detect a significant association. It indicated that common genetic variations in CDK5 (Montrer CDK5 Anticorps) genes might not play a role in the genetic predisposition to autism.

  6. Analysis of the RT-PCR prducts of the CABLES1 gene showed eight intragenic deletions in its mRNA transcripts; 5/8 are the result of RNA splicing.

  7. Mechanisms of CABLES1 gene inactivation in ovarian cancer development are reported.

Mouse (Murine) Cdk5 and Abl Enzyme Substrate 1 (CABLES1) interaction partners

  1. Loss of Cables1 enhances tumor progression in the Apc (Montrer APC Anticorps)(Min/+) mouse model and activates the Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) signaling pathway. Cables1 is a tumor suppressor gene on chromosome 18q in this in vivo mouse model.

  2. Agenesis of the corpus callosum frequency in Cables1(+/TAS (Montrer MAP3K4 Anticorps)) mice was significantly lower than that in Cables1(-/TAS (Montrer MAP3K4 Anticorps)) mice, indicating that wild-type Cables1 interfered with the dominant negative effect of Cables1(TAS (Montrer MAP3K4 Anticorps)).

  3. Data show that oocytes lacking Cables1 exhibit lower basal levels of TAp63alpha and reduced accumulation of phosphorylated TAp63alpha in response to genotoxic stress.

  4. Cables1 null mice exhibit a significant expansion of oocyte numbers at the expense of oocyte quality throughout adulthood.

Cdk5 and Abl Enzyme Substrate 1 (CABLES1) profil antigène

Profil protéine

This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CABLES1

  • Cdk5 and Abl enzyme substrate 1 (CABLES1) anticorps
  • Cdk5 and Abl enzyme substrate 1 (cables1) anticorps
  • Cdk5 and Abl enzyme substrate 1 (CpipJ_CPIJ019832) anticorps
  • CDK5 and Abl enzyme substrate 1 (Cables1) anticorps
  • Cdk5 and Abl enzyme substrate 1 (Cables1) anticorps
  • CABL1 anticorps
  • Cables anticorps
  • CABLES1 anticorps
  • HsT2563 anticorps
  • ik3-1 anticorps
  • si:dkey-2p18.3 anticorps

Protein level used designations for CABLES1

Cdk5 and Abl enzyme substrate 1 , CDK5 and ABL1 enzyme substrate 1 , CDK5 and ABL1 enzyme substrate 1-like , interactor with CDK3 1 , cdk3-binding protein ik3-1 , interactor-1 with cdk3

GENE ID SPECIES
455335 Pan troglodytes
100059359 Equus caballus
100126070 Danio rerio
100345850 Oryctolagus cuniculus
100479459 Ailuropoda melanoleuca
6054063 Culex quinquefasciatus
100562423 Anolis carolinensis
100603520 Nomascus leucogenys
91768 Homo sapiens
63955 Mus musculus
768914 Gallus gallus
100682687 Canis lupus familiaris
100526114 Sus scrofa
100138286 Bos taurus
307585 Rattus norvegicus
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