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CDON encodes a cell surface receptor that is a member of the immunoglobulin superfamily. De plus, nous expédions Cell Adhesion Molecule-Related/down-Regulated By Oncogenes Protéines (8) et Cell Adhesion Molecule-Related/down-Regulated By Oncogenes Kits (4) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal CDON Primary Antibody pour ELISA - ABIN1999437
Wegorzewska, Krauss, Kang: Overexpression of the immunoglobulin superfamily members CDO and BOC enhances differentiation of the human rhabdomyosarcoma cell line RD. dans Molecular carcinogenesis 2003
Show all 2 references for ABIN1999437
Cow (Bovine) Polyclonal CDON Primary Antibody pour ELISA, ICC - ABIN4297093
Kang, Feinleib, Knox, Ketteringham, Krauss: Promyogenic members of the Ig and cadherin families associate to positively regulate differentiation. dans Proceedings of the National Academy of Sciences of the United States of America 2003
Cdon is required to localize N-cadherin (Montrer CDH2 Anticorps) to the cell membrane in migratory neural crest cells for directed migration.
In the developing optic vesicle, Cdon predominantly localizes to the basolateral side of neuroepithelial cells, promotes the enlargement of the neuroepithelial basal end-foot and traps Hedgehog (Montrer SHH Anticorps) protein, thereby limiting its dispersion.
We identified a novel heterozygous nonsense CDON mutation in a case of Pituitary Stalk Interruption Syndrome who presented with neonatal hypoglycemia and cholestasis
CDO (Montrer CDO1 Anticorps) is required for proliferation and survival of lung cancer cells via Hh signaling.
These data support the view that cell-adhesion molecule (Montrer MCAM Anticorps)-related/downregulated by oncogenes (CDON) acts as a tumor suppressor in neuroblastomas, and that CDON is tightly regulated by miRNAs.
Single-nucleotide polymorphism in CDON is associated with biochemical recurrence in prostate cancer.
Mutations in the CDON cause holoprosencephaly. (Review)
We found that CDON is overexpressed in prostate cancer
CDON must associate with both ligand and other hedgehog (Montrer SHH Anticorps)-receptor components, particularly PTCH1 (Montrer PTCH1 Anticorps), for signaling to occur and disruption of the latter interactions is a mechanism of holoprosencephaly.
Hedgehog (Montrer SHH Anticorps) proteins interact with cell adhesion molecule (Montrer MCAM Anticorps), down-regulated by oncogenes (CDO (Montrer CDO1 Anticorps)) and brother of CDO (BOC (Montrer BOC Anticorps)) in a conserved manner
CDO (Montrer CDO1 Anticorps) and BOC (Montrer BOC Anticorps) play a role in differentiation of cells in the skeletal muscle lineage
CDO (Montrer CDO1 Anticorps) and BOC (Montrer BOC Anticorps) forms complexes with specific cadherins that mediate some of the promyogenic effects of cell-cell contact.
that Cdon participates in oligodendrocyte differentiation and myelination, most likely in the initial stages of development
Suggest that Cdo (Montrer CDO1 Anticorps) is required for the full Shh (Montrer SHH Anticorps) signaling activation to induce efficient dopaminergic neuron neurogenesis.
Rescue of holoprosencephaly in fetal alcohol-exposed Cdon mutant mice by reduced gene dosage of Ptch1 (Montrer PTCH1 Anticorps).
Cx43 (Montrer GJA1 Anticorps) physically interacts with Cdo (Montrer CDO1 Anticorps) to form dynamic complexes during myoblast differentiation
Stim1 (Montrer STIM1 Anticorps) protein levels were decreased in Cdo (Montrer CDO1 Anticorps)-deficient perinatal hindlimb muscles or primary myoblasts; this correlates with defective NFATc3 (Montrer NFATC3 Anticorps) activation in Cdo (Montrer CDO1 Anticorps)(-/-) myoblasts upon differentiation.
ASK1 (Montrer MAP3K5 Anticorps) and TAK1 (Montrer NR2C2 Anticorps) function as MAP3 kinases in Cdo (Montrer CDO1 Anticorps)-mediated p38MAPK (Montrer MAPK14 Anticorps) activation to promote myogenic differentiation.
Gas1 (Montrer GAS1 Anticorps) cooperates with Cdo (Montrer CDO1 Anticorps) and promotes myogenic differentiation via activation of p38MAPK (Montrer MAPK14 Anticorps)
the Integrin/FAK (Montrer PTK2 Anticorps) signaling pathway regulates the expression of the promyogenic factors, Cdo (Montrer CDO1 Anticorps), MyoD (Montrer MYOD1 Anticorps) and Cdc42 (Montrer CDC42 Anticorps) which are required for myoblast differentiation
Cdo (Montrer CDO1 Anticorps);Boc (Montrer BOC Anticorps) double mutants on a largely Cdo (Montrer CDO1 Anticorps)-resistant genetic background have lobar holoprosencephaly.
This gene encodes a cell surface receptor that is a member of the immunoglobulin superfamily. The encoded protein contains three fibronectin type III domains and five immunoglobulin-like C2-type domains. This protein is a member of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells and positively regulates myogenesis.
Cdon homolog (mouse)
, surface glycoprotein, Ig superfamily member
, cell adhesion molecule-related/down-regulated by oncogenes
, Cdon homolog
, immunoglobulin superfamily member
, CAM-related/down-regulated by oncogenes
, immunoglobulin superfamily member CDO
, oncogene-regulated cell adhesion molecule
, cysteine dioxygenase type 1
, cysteine dioxygenase type I