anti-Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) Anticorps

CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. De plus, nous expédions CDC20 Protéines (6) et CDC20 Kits (1) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CDC20 991 Q12834
CDC20 107995 Q9JJ66
CDC20 64515 Q62623
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Top anti-CDC20 Anticorps sur anticorps-enligne.fr

Showing 10 out of 218 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from Jurkat/HeLa cells, using p55CDC Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), IP Western Blot: CDC20 Antibody [ABIN252980] - Detection of Human CDC20 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-CDC20 antibody ABIN252980 used for IP at 3 mcg/mg lysate. CDC20 was also immunoprecipitated by rabbit anti- CDC20 antibody ABIN252981, which recognizes a downstream epitope. Immunohistochemistry-Paraffin: Cdc20 Antibody [ABIN2529807] - Detection of Mouse CDC20 by Immunohistochemistry. FFPE section of mouse teratoma. Affinity purified rabbit anti-CDC20 used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit. 100 μL Connectez-vous pour afficher 7 to 9 Days
$486.94
Détails
Humain Lapin Inconjugué WB Western blot analysis of CDC20 expression in Raji (A), HEK293T (B), HL60 (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), IP, PLA, WB Western Blot and Immunoprecipitation: CDC20 Antibody [ABIN252981] - Detection of Human CDC20 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) and 293T (T, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-CDC20 antibody ABIN252981 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. CDC20 was also immunoprecipitated by rabbit anti-CDC20 antibody ABIN252980, which recognizes an upstream epitope. Immunohistochemistry-Paraffin: Cdc20 Antibody [ABIN2529818] - FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-CDC20 used at a dilution of 1:250. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$486.94
Détails
Humain Lapin Inconjugué EIA, IP, WB Conjugation pathways for ubiquitin and ubiquitin-like modifiers (UBLs). Most modifiers mature by proteolytic processing from inactive precursors (a, amino acid). Arrowheads point to the cleavage sites. Ubiquitin is expressed either as polyubiquitin or as a fusion with ribosomal proteins. Conjugation requires activating (E1) and conjugating (E2) enzymes that form thiolesters (S) with the modifiers. Modification of cullins by RUB involves SCF(SKP1/cullin-1/F-box protein) /CBC(cullin-2/elongin B/elonginC) -like E3 enzymes that are also involved in ubiquitination. In contrast to ubiquitin, the UBLs do not seem to form multi-UBL chains. UCRP(ISG15) resembles two ubiquitin moieties linked headto- tail. Whether HUB1 functions as a modifier is currently unclear. APG12 and URM1 are distinct from the other modifiers because they are unrelated in sequence to ubiquitin. Data contributed by S.Jentsch, see references below. 0.1 mL Connectez-vous pour afficher 6 to 8 Days
$419.10
Détails
Humain Lapin Inconjugué IHC (p), WB   100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Humain Lapin Inconjugué IP, WB Conjugation pathways for ubiquitin and ubiquitin-like modifiers (UBLs). Most modifiers mature by proteolytic processing from inactive precursors (a 100 μL Connectez-vous pour afficher 1 to 2 Days
$379.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC (p), WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 7 to 9 Days
$676.50
Détails
Rat Lapin Inconjugué WB Anti-Cdc20 antibody, Western blotting Lane 1: Rat Thymus Tissue Lysate Lane 2: Rat Spleen Tissue Lysate 100 μg Connectez-vous pour afficher 4 to 6 Days
$200.00
Détails

CDC20 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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Mouse (Murine) , ,


Rat (Rattus)


anti-CDC20 Anticorps mieux référencés

  1. Human Polyclonal CDC20 Primary Antibody pour ICC, IF - ABIN252981 : Di Fiore, Pines: How cyclin A destruction escapes the spindle assembly checkpoint. dans The Journal of cell biology 2010 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal CDC20 Primary Antibody pour ICC, IF - ABIN252980 : Ahlskog, Björk, Elsing, Aspelin, Kallio, Roos-Mattjus, Sistonen: Anaphase-promoting complex/cyclosome participates in the acute response to protein-damaging stress. dans Molecular and cellular biology 2010 (PubMed)
    Show all 2 Pubmed References

  3. Xenopus laevis Monoclonal CDC20 Primary Antibody pour CyTOF, ELISA - ABIN251088 : Sackton, Dimova, Zeng, Tian, Zhang, Sackton, Meaders, Pfaff, Sigoillot, Yu, Luo, King: Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C. dans Nature 2014 (PubMed)

  4. Human Polyclonal CDC20 Primary Antibody pour IP, WB - ABIN233786 : Yamamuro, Kano, Naito: Functions of FZR1 and CDC20, activators of the anaphase-promoting complex, during meiotic maturation of swine oocytes. dans Biology of reproduction 2008 (PubMed)

  5. Human Polyclonal CDC20 Primary Antibody pour IHC, IHC (p) - ABIN4296835 : Onul, Colvard, Paradise, Elseth, Vesper, Gouvas, Deliu, Garcia, Pestle, Radosevich: Application of immunohistochemical staining to detect antigen destruction as a measure of tissue damage. dans The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2012 (PubMed)

Plus d’anticorps contre CDC20 partenaires d’interaction

Human Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) interaction partners

  1. The ABBA (Montrer MTSS1L Anticorps)-KEN (Montrer PCNT Anticorps)-ABBA (Montrer MTSS1L Anticorps) amino acid motif cassette holds the Mitotic Checkpoint (Montrer BUB3 Anticorps) Complex (MCC (Montrer MCC Anticorps)) onto the Anaphase-Promoting Complex-Cyclosome (APC (Montrer APC Anticorps)/C) by binding the two Cdc20 molecules in the MCC (Montrer MCC Anticorps)-APC (Montrer APC Anticorps)/C complex.

  2. It discuses the roles of Cdc20 in SAC (Montrer ADCY10 Anticorps) signalling and mitotic exit, describe how the integration of traditional approaches with emerging technologies has revealed new details of Cdc20 functions, comment about the potential of Cdc20 as a therapeutic target for the treatment of human malignancies.

  3. Prostate cancer-derived SPOP (Montrer SPOP Anticorps) mutants failed to interact with Cdc20 to promote its degradation. As a result, SPOP (Montrer SPOP Anticorps)-deficient prostate cancer cells with elevated Cdc20 expression became resistant to a pharmacological Cdc20 inhibitor.

  4. High CDC20 expression is associated with metastatic castration-resistant prostate cancer growth and reduces chemosensitivity .

  5. These results provide novel insight into the mechanisms underlying the aberrant capability of NUP98 (Montrer NUP98 Anticorps) oncoproteins to interact with APC (Montrer APC Anticorps)/C(Cdc20) and to interfere with its function.

  6. In lung adenocarcinoma patients, overexpression of cell division cycle 20 was significantly associated with bigger primary tumor size, higher MKI67 (Montrer MKI67 Anticorps) level, higher DNA ploidy level, and poor prognosis.

  7. CDC20 may have a role in carcinoma of the breast, colon, endometrium, and prostate

  8. Overexpression of Cdc20 may serve as an independent predictor for biochemical recurrence in patients of clinically localized prostate cancer undergoing laparoscopic radical prostatectomy without neoadjuvant therapy.

  9. Results show that CYP1B1 (Montrer CYP1B1 Anticorps) may promote renal cell carcinoma (Montrer MOK Anticorps) development by inducing CDC20 expression and inhibiting apoptosis through the down-regulation of DAPK1 (Montrer DAPK1 Anticorps).

  10. Study describes a positive feedback loop centred on cyclin A2 (Montrer CCNA2 Anticorps)-Cdk2 (Montrer CDK2 Anticorps) inhibition of interphase APC (Montrer APC Anticorps)/C-Cdc20 to allow further cyclin A2 (Montrer CCNA2 Anticorps) accumulation and mitotic entry.

Xenopus laevis Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) interaction partners

  1. Cdc20 auto-ubiquitylation does not play a major role in terminating Cdc20 activation.

  2. Dephosphorylation of Cdc20 is required for its loading and activation of the APC/C ubiquitin ligase.

  3. A role for the fizzy/cdc20 family of proteins in activation of the APC (Montrer APC Anticorps)/C distinct from substrate recruitment is reported.

Mouse (Murine) Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) interaction partners

  1. Cdc20 hypomorphism causes chromatin bridging and chromosome misalignment, revealing a requirement for Cdc20 in efficient sister chromosome separation and chromosome-microtubule attachment.

  2. The physiologically effective threshold level of Cdc20 is high for female meiosis I.

  3. Results indicate that Cdc20 also contributes to post-anaphase activation of the APC (Montrer APC Anticorps)/C.

  4. The seven tandem WD motifs of Cdc20 they are required for speriolin binding and for localization of Cdc20 to the centrosomes and nucleus, suggesting that speriolin might regulate or stabilize the folding of Cdc20 during meiosis in spermatogenic cells

  5. Data suggest that Mad2 (Montrer MXI1 Anticorps) and BubR1 (Montrer BUB1B Anticorps) must cooperate to inhibit Cdc20 activity.

  6. Cdc20 is degraded through two independent degradation signals (degrons), the KEN (Montrer PCNT Anticorps) box and a newly described CRY (Montrer CRY2 Anticorps) box.

  7. Cdc20 and securin (Montrer PTTG1 Anticorps) double mutant embryos could not maintain the metaphase arrest, suggesting a role of securin (Montrer PTTG1 Anticorps) in preventing mitotic exit

  8. Expression of the cdc20 gene is down-regulated by zif268 (Montrer EGR1 Anticorps) in neuronal cells; altered expression of proteasome-regulatory genes following zif268 (Montrer EGR1 Anticorps) induction may be a key component of long-lasting CNS plasticity.

  9. Cdc20 is required for the anaphase onset of the first meiosis but not the second meiosis in mouse oocytes

  10. findings suggest a novel function of HSF1 (Montrer HSF1 Anticorps) frequently overexpressed in cancer cells, to inhibit APC (Montrer APC Anticorps)/C activity by interacting with Cdc20, and to result in aneuploidy development and genomic instability

Pig (Porcine) Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) interaction partners

  1. porcine FZR1 (Montrer FZR1 Anticorps) and CDC20 work on the maintenance of meiotic arrest at the first meiotic prophase and on the exit from M1

CDC20 profil antigène

Profil protéine

CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation.

Gene names and symbols associated with CDC20

  • cell division cycle 20 (cdc20) anticorps
  • cell division cycle 20 (CDC20) anticorps
  • cell division cycle 20 L homeolog (cdc20.L) anticorps
  • cell division cycle 20 (Cdc20) anticorps
  • cell division cycle 20 homolog (S. cerevisiae) (CDC20) anticorps
  • 2310042N09Rik anticorps
  • bA276H19.3 anticorps
  • C87100 anticorps
  • CDC20A anticorps
  • fizzy1 anticorps
  • p55CDC anticorps
  • X-FZY anticorps

Protein level used designations for CDC20

cell division cycle 20 homolog , CDC20 cell division cycle 20 homolog , cell division cycle protein 20 homolog , fizzy1 , mmCdc20 , cell cycle protein p55CDC , p55CDC

GENE ID SPECIES
394542 Xenopus (Silurana) tropicalis
991 Homo sapiens
398044 Xenopus laevis
107995 Mus musculus
64515 Rattus norvegicus
424563 Gallus gallus
482534 Canis lupus familiaris
397379 Sus scrofa
515376 Bos taurus
Fournisseurs de qualité sélectionnés pour anti-CDC20 (CDC20) Anticorps
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