Ceroid-Lipofuscinosis, Neuronal 3 (CLN3) Kits ELISA

CLN3 encodes a protein that is involved in lysosomal function. De plus, nous expédions CLN3 Anticorps (38) et CLN3 Protéines (4) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
Anti-Humain CLN3 CLN3 1201 Q13286
Anti-Souris CLN3 CLN3 12752 Q61124
Anti-Rat CLN3 CLN3 293485  
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Plus Kits ELISA pour CLN3 partenaires d'interaction

Mouse (Murine) Ceroid-Lipofuscinosis, Neuronal 3 (CLN3) interaction partners

  1. Our subcellular localization study in neurons refines the localization and subcellular targeting of CLN3 to late endosomal-lysosomal compartments

  2. findings in two distinct lysosome-related degradative pathways constitute the first description of a deficit in the retinal pigment epithelium caused by loss of CLN3

  3. The small GTPase (Montrer RACGAP1 Kits ELISA) Cdc42 (Montrer CDC42 Kits ELISA) is misregulated in the absence of CLN3, and thus may be a common link to multiple cellular defects.

  4. Rssults suggested that CLN2 (Montrer TPP1 Kits ELISA), CLN3 and CLN5 (Montrer CLN5 Kits ELISA) genes may play an important role in early embryonal neurogenesis.

  5. The aim of our study was to investigate the visual disease progression in the Cln3 (Deltaex7/8) mice.

  6. CLN3 facilitates transport of microdomain-associated proteins.

  7. results demonstrate altered glutamate (Montrer GRIN1 Kits ELISA) receptor function in Cln3(Deltaex7/8) neurons and suggest that both AMPA (Montrer GRIA3 Kits ELISA) and NMDA receptors are potential therapeutic targets in juvenile neuronal ceroid lipofuscinosis (Montrer CLN6 Kits ELISA)

  8. The migration defect in Cln3(-/-) results, in part, from the loss of the CLN3-myosin-IIB (Montrer MYH10 Kits ELISA) interaction.

  9. Findings suggest an osmoregulated role for CLN3p in renal medullary control of water and K(+) balance.

  10. Cln3(Deltaex7/8) knock-in mice with the common juvenile-onset neuronal ceroid lipofuscinosis (Montrer CLN6 Kits ELISA) (JNCL; Batten disease) mutation exhibit progressive neurologic disease that begins before birth.

Human Ceroid-Lipofuscinosis, Neuronal 3 (CLN3) interaction partners

  1. The age at onset and natural progression of retinal disease differs greatly between syndromic and nonsyndromic CLN3 disease, which may be associated with genotypic differences.

  2. CLN3 knockdown inhibits cell proliferation and induces G0/G1 cell cycle arrest in the A2780 cell line and its drug-resistant sub-lines.

  3. The membrane topology of human CLN3 protein.

  4. The eyes and vision of heterozygous carriers of CLN3 disease showed normal features when compared to a control group, which controverts a previously suggested retinal dysfunction in these subjects.

  5. This new model system, which allows for the study of Cln3 function in both single cells and a multicellular organism, together with the observation that expression of human CLN3 restores abnormalities in Dictyostelium cln3- cells

  6. These results further support an important role for the CLN3 protein in intracellular Ca(2 (Montrer CA2 Kits ELISA)+) handling and in autophagic pathway flux and establish a powerful new platform for therapeutic screening.

  7. CLN3 mutation is associated with neuronal ceroid lipofuscinosis (Montrer CLN6 Kits ELISA).

  8. Genetic testing for CLN3 should be considered in autophagic vacuolar myopathy (AVM), with autophagic vacuoles and sarcolemmal features.

  9. CLN3 was identified as a novel disease gene for non-syndromic retinal diseases as supported by five unrelated patient families in this study.

  10. CLN3 is involved in the response and adaptation to cellular stress.

Cow (Bovine) Ceroid-Lipofuscinosis, Neuronal 3 (CLN3) interaction partners

  1. The candidate genes for bovine Neuronal Ceroid Lipofuscinosis (Montrer CLN6 Kits ELISA), CLN3, CLN5 (Montrer CLN5 Kits ELISA) and CLN6 (Montrer CLN6 Kits ELISA), have been mapped to facilitate linkage analysis in cattle and sheep.

CLN3 profil antigène

Antigen Summary

This gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with CLN3

  • CLN3, battenin (CLN3) anticorps
  • ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) (Cln3) anticorps
  • ceroid-lipofuscinosis, neuronal 3 (cln3) anticorps
  • battenin (PTRG_05620) anticorps
  • CLN3, battenin (Cln3) anticorps
  • battenin (LOC410860) anticorps
  • ceroid-lipofuscinosis, neuronal 3 L homeolog (cln3.L) anticorps
  • uncharacterized LOC467935 (LOC467935) anticorps
  • AI323623 anticorps
  • bts anticorps
  • GB12798 anticorps
  • JNCL anticorps
  • MGC80041 anticorps
  • zgc:92244 anticorps

Protein level used designations for CLN3

batten disease protein , battenin , Cln3p , ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) , ceroid-lipofuscinosis, neuronal 3 , ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) , ceroid-lipofuscinosis, neuronal 3, juvenile , battenin-like

1201 Homo sapiens
12752 Mus musculus
492340 Danio rerio
6343873 Pyrenophora tritici-repentis Pt-1C-BFP
293485 Rattus norvegicus
410860 Apis mellifera
446498 Xenopus laevis
467935 Pan troglodytes
479794 Canis lupus familiaris
504799 Bos taurus
100009244 Oryctolagus cuniculus
100124328 Xenopus (Silurana) tropicalis
100127354 Sus scrofa
100388249 Callithrix jacchus
100457403 Pongo abelii
100583151 Nomascus leucogenys
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