anti-Chloride Intracellular Channel 4 (CLIC4) Anticorps

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. De plus, nous expédions CLIC4 Protéines (20) et CLIC4 Kits (8) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CLIC4 25932 Q9Y696
CLIC4 83718 Q9Z0W7
CLIC4 29876 Q9QYB1
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Top anti-CLIC4 Anticorps sur anticorps-enligne.fr

Showing 10 out of 107 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-CLIC4 Antibody Titration: </b>2.5ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Humain Chèvre Inconjugué ELISA, WB ABIN190810 (0.1µg/ml) staining of human kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN190810 (5ug/ml) staining of min6 cells transiently expressing mouse Clic4. Nuclear counter staining by Hoechst. Data kindly provided by Dr. Virginie Nepote, Lausanne University, Switzerland. 100 μg Connectez-vous pour afficher 6 to 7 Days
$326.89
Détails
Humain Chèvre Inconjugué ELISA, ICC, IF, IHC (p), WB Western Blot: CLIC4 Antibody [NBP1-00172] - (0.1ug/ml) staining of human kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Immunocytochemistry/Immunofluorescence: CLIC4 Antibody [NBP1-00172] - (5ug/ml) staining of min6 cells transiently expressing mouse Clic4. Nuclear counter staining by Hoechst. Data kindly provided by Dr. Virginie Nepote, Lausanne University, Switzerland. 0.1 mg Connectez-vous pour afficher 7 to 9 Days
$408.19
Détails
Humain Lapin Inconjugué IHC, ELISA, WB Western blot analysis of extracts from HT-29 cells, using CLIC4 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human lymph node tissue, using CLIC4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Souris Inconjugué IHC (p), WB Western blot analysis of anti-CLIC4 Monoclonal Antibody (ABIN387769) in Hela cell line lysates. CLIC4(arrow) was detected using the ascites Mab. Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with CLIC4 Antibody (ABIN387769), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.1 mL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Chèvre Inconjugué IF, IHC (p), ELISA, WB Human Heart (formalin-fixed, paraffin-embedded) stained with CLIC4 antibody ABIN337111 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 7 to 9 Days
$451.00
Détails
Humain Lapin Inconjugué IP, ELISA, WB 100 μg Connectez-vous pour afficher 20 to 21 Days
$218.90
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB   0.1 mg Connectez-vous pour afficher 10 to 12 Days
$357.50
Détails
Chien Chèvre Inconjugué EIA, IF, IHC (p), WB 50 μg Connectez-vous pour afficher 6 to 8 Days
$500.50
Détails
Cobaye Lapin Inconjugué IHC (p), WB Lung, respiratory epithelium 100 μg Connectez-vous pour afficher 7 to 9 Days
$451.00
Détails

CLIC4 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-CLIC4 Anticorps mieux référencés

  1. Human Polyclonal CLIC4 Primary Antibody pour ICC, IF - ABIN4299203 : Lomnytska, Becker, Gemoll, Lundgren, Habermann, Olsson, Bodin, Engström, Hellman, Hellman, Hellström, Andersson, Mints, Auer: Impact of genomic stability on protein expression in endometrioid endometrial cancer. dans British journal of cancer 2012 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal CLIC4 Primary Antibody pour ELISA, ICC - ABIN314274 : Suh, Crutchley, Koochek, Ryscavage, Bhat, Tanaka, Oshima, Fitzgerald, Yuspa: Reciprocal modifications of CLIC4 in tumor epithelium and stroma mark malignant progression of multiple human cancers. dans Clinical cancer research : an official journal of the American Association for Cancer Research 2007 (PubMed)

Plus d’anticorps contre CLIC4 partenaires d’interaction

Human Chloride Intracellular Channel 4 (CLIC4) interaction partners

  1. CLIC4 and Ihh (Montrer IHH Anticorps) could serve as biological markers for the progression, metastasis and/or invasiveness of pancreatic ductal adenocarcinoma.

  2. in malignant pleural mesothelioma, the gene expressions of CLIC3 (Montrer CLIC3 Anticorps) and CLIC4 were significantly increased compared to controls

  3. CLIC1 (Montrer CLIC1 Anticorps) and CLIC4 are overexpressed in specific tumor types or their corresponding stroma and change localization and function from hydrophilic cytosolic to integral transmembrane proteins. (Review)

  4. CLIC4 knockdown decreases cell-matrix adhesion, cell spreading and integrin signaling, whereas it increases cell motility.

  5. CLIC4, ERp29 (Montrer ERP29 Anticorps), and Smac/DIABLO (Montrer DIABLO Anticorps) integrated into a novel panel based on cancer stem-like cells in association with metastasis stratify the prognostic risks of colorectal cancer.

  6. This study investigated the proteome modulated by oncogenic KRAS in immortalized airway epithelial cells.

  7. Increased CLIC4 expression is an early manifestation and mediator of endothelial dysfunction in pulmonary hypertension.

  8. CLIC4 increases tumor cell migration and invasion in a TGF-beta (Montrer TGFB1 Anticorps)-dependent manner.

  9. In addition to CLIC1 (Montrer CLIC1 Anticorps) and TPM1 (Montrer TPM1 Anticorps), which were the proteins initially discovered in a xenograft mouse model, CLIC4, TPM2 (Montrer TPM2 Anticorps), TPM3 (Montrer TPM3 Anticorps), and TPM4 (Montrer TPM4 Anticorps) were present in ovarian cancer patient sera at significantly elevated levels compared with controls.

  10. Our data indicate that CLIC4 protein may be a key element in the apoptotic response to oxidative stress.

Mouse (Murine) Chloride Intracellular Channel 4 (CLIC4) interaction partners

  1. Data, including data from studies in primary cells from knockout mice, suggest Clic1 (Montrer CLIC1 Anticorps) and Clic4 participate in signaling interleukin 1beta secretion and in activation of Nlrp3 (Montrer NLRP3 Anticorps) inflammasomes; in LPS (Montrer TLR4 Anticorps) macrophage activation, Clic1 (Montrer CLIC1 Anticorps) and Clic4 are translocated to nucleus/cell membranes. (Clic1 (Montrer CLIC1 Anticorps) = chloride intracellular channel 1 (Montrer CLIC1 Anticorps); Clic4 = chloride intracellular channel 4, mitochondrial; Nlrp3 (Montrer NLRP3 Anticorps) = NLR family pyrin domain containing 3 (Montrer NLRP3 Anticorps))

  2. study reports an alternately-spliced form of Smad7 (Montrer SMAD7 Anticorps), Smad7Delta, that is induced by TGF-beta (Montrer TGFB1 Anticorps) and CLIC4, is a dominant inhibitor of Smad7 (Montrer SMAD7 Anticorps) and enhances TGF-beta (Montrer TGFB1 Anticorps) signaling

  3. The findings indicate that CLIC4/CLIC5A-mediated ERM (Montrer ETV5 Anticorps) activation is required for maintenance of the glomerular capillary architecture.

  4. CLIC4 is not required for collaterogenesis but is essential for perinatal maturation of nascent collaterals through a mechanism that supports VEGF signaling.

  5. However, the absence of CLIC4 has no significant impact on the extent of functional recovery or fibrosis following acute injury.

  6. Data suggest that compartmentalized expression of chloride intracellular channel 4 (CLIC4) in specific adult tissues and cells provides a focus to explore potential functions of this protein.

  7. Increased CLIC4 expression is an early manifestation and mediator of endothelial dysfunction in pulmonary hypertension.

  8. These results indicate that CLIC4 participates in skin healing and corneal wound reepithelialization through enhancement of epithelial migration by a mechanism that may involve a compromised TGF-beta (Montrer TGFB1 Anticorps) pathway.

  9. Data suggest that iNOS (Montrer NOS2 Anticorps)-induced nuclear CLIC4 is an essential part of the macrophage deactivation program.

  10. CLIC4 is required for an optimal macrophage response to diverse pathogens. CLIC4-null these findings suggest that CLIC4 is an LPS (Montrer TLR4 Anticorps)-induced product that can serve as a positive regulator of LPS (Montrer TLR4 Anticorps) signaling

CLIC4 profil antigène

Profil protéine

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family\; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).

Gene names and symbols associated with CLIC4

  • chloride intracellular channel 4 (clic4) anticorps
  • chloride intracellular channel 5 (clic5) anticorps
  • chloride intracellular channel 4 (CLIC4) anticorps
  • chloride intracellular channel 4 S homeolog (clic4.S) anticorps
  • chloride intracellular channel 4 (Clic4) anticorps
  • chloride intracellular channel 4 (mitochondrial) (Clic4) anticorps
  • cb142 anticorps
  • CLIC4 anticorps
  • CLIC4L anticorps
  • D0Jmb3 anticorps
  • DKFZp459A0325 anticorps
  • H1 anticorps
  • huH1 anticorps
  • mc3s5 anticorps
  • MGC79614 anticorps
  • MGC89006 anticorps
  • mtCLIC anticorps
  • p64H1 anticorps
  • TU-74 anticorps
  • wu:fb33c05 anticorps
  • wu:fc30h10 anticorps
  • xclic4 anticorps

Protein level used designations for CLIC4

chloride intracellular channel 4 , Chloride intracellular channel protein 4 , chloride intracellular channel protein 4 , chloride intracellular channel 4 like , intracellular chloride ion channel protein p64H1 , chloride intracellular channel 4 (mitochondrial) , mitochondrial chloride intracellular channel 4 , mc3s5/mtCLIC

GENE ID SPECIES
448566 Xenopus (Silurana) tropicalis
493290 Xenopus (Silurana) tropicalis
712337 Macaca mulatta
749398 Pan troglodytes
100169733 Pongo abelii
100528919 Ictalurus punctatus
399410 Xenopus laevis
25932 Homo sapiens
487367 Canis lupus familiaris
286823 Bos taurus
83718 Rattus norvegicus
368255 Danio rerio
419595 Gallus gallus
29876 Mus musculus
Fournisseurs de qualité sélectionnés pour anti-CLIC4 (CLIC4) Anticorps
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