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Coagulation Factor VIII (F8) Kits ELISA

F8 encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. De plus, nous expédions Factor VIII Anticorps (337) et Factor VIII Protéines (32) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
F8 14069 Q06194
F8 2157 P00451
F8 302470  
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Top Factor VIII Kits ELISA sur anticorps-enligne.fr

Showing 10 out of 55 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Chien 31.25 ng/mL 125-8000 ng/mL Typical standard curve 96 Tests Connectez-vous pour afficher 13 to 17 Days
874,71 €
Détails
Souris 0.078 ng/mL 0.312-20 ng/mL Typical standard curve 96 Tests Connectez-vous pour afficher 11 to 15 Days
874,71 €
Détails
Humain 30 pg/mL 78-5.000 pg/mL 96 Tests Connectez-vous pour afficher 11 to 15 Days
562,96 €
Détails
Porc 0.469 ng/mL 0.781-50 ng/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
580,95 €
Détails
Singe 0.188 ng/mL 0.313-20 ng/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
580,95 €
Détails
Poulet 0.188 ng/mL 0.313-20 ng/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
580,95 €
Détails
Lapin 18.75 pg/mL 31.25-2000 pg/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
580,95 €
Détails
Rat 4.688 pg/mL 7.813-500 pg/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
600,00 €
Détails
Humain
  96 Tests Connectez-vous pour afficher 6 to 8 Days
410,71 €
Détails
Chévre
  96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
Détails

Plus Kits ELISA pour Factor VIII partenaires d'interaction

Zebrafish Coagulation Factor VIII (F8) interaction partners

  1. gene is flanked by factor VII (Montrer TH Kits ELISA) and factor X genes; gene encodes a protein homologous to factor VII (Montrer TH Kits ELISA), but lacks critical residues for factor VII (Montrer TH Kits ELISA) activity; functions as an inhibitor of blood coagulation in biochemical assays using zebrafish or human plasmas

Mouse (Murine) Coagulation Factor VIII (F8) interaction partners

  1. the results indicate that residues in the C1 and/or C2 domains of factor VIII are implicated in immunogenic factor VIII uptake, at least in vitro Conversely, in vivo, the binding to endogenous von Willebrand factor (Montrer VWF Kits ELISA) masks the reducing effect of mutations in the C domains on factor VIII immunogenicity.

  2. data demonstrate that infusion of platelets containing FVIII triggers neither primary nor memory anti-FVIII immune response in FVIII(null) mice

  3. Both platelet-VWF (Montrer VWF Kits ELISA) and plasma-VWF (Montrer VWF Kits ELISA) are required for optimal platelet-derived FVIII gene therapy for hemophilia A in the presence of inhibitors.

  4. These data support the investigation of FVIII orthologs as treatment modalities in both the congenital and acquired FVIII inhibitor settings.

  5. Activatable bioengineered FIX molecules with FVIII-independent activity might be a promising tool for improving hemophilia A treatment, especially for patients with inhibitors.

  6. This study demonstrated that FVIIIa interacts with Low-density lipoprotein receptor-related protein 1 (Montrer LRP1 Kits ELISA) cluster III.

  7. a fragment containing only approximately 20% of the VWF (Montrer VWF Kits ELISA) sequence is sufficient to support FVIII stability in vivo

  8. Endothelial cells from multiple, but not all, tissues contribute to the plasma FVIII pool in the mouse.

  9. Endothelial cells are the predominant, and possibly exclusive, source of plasma FVIII.

  10. Micro-computed tomography analysis of distal tibia metaphyses also revealed for the first time a major impact of the FVIII/thrombin (Montrer F2 Kits ELISA)/PAR1 (Montrer F2R Kits ELISA) axis on the dynamic bone structure, showing reduced bone.

Human Coagulation Factor VIII (F8) interaction partners

  1. the results indicate that residues in the C1 and/or C2 domains of factor VIII are implicated in immunogenic factor VIII uptake, at least in vitro Conversely, in vivo, the binding to endogenous von Willebrand factor (Montrer VWF Kits ELISA) masks the reducing effect of mutations in the C domains on factor VIII immunogenicity.

  2. Our finding that the C2-domain of FVIII can be replaced by that of FV without compromising FVIII activity may have translational implications.

  3. Galectin-1 (Montrer LGALS1 Kits ELISA) and Galectin-3 (Montrer LGALS3 Kits ELISA) are novel-binding partners for human FVIII. Gal-1 (Montrer LGALS1 Kits ELISA) binding can influence the procoagulant activity of FVIII.

  4. although fVIII bound avidly to soluble forms of clusters II and IV from LRP1 (Montrer LRP1 Kits ELISA), only soluble cluster IV competed with the binding of fVIII to full-length LRP1 (Montrer LRP1 Kits ELISA), revealing that cluster IV represents the major fVIII binding site in LRP1 (Montrer LRP1 Kits ELISA).

  5. The FVIII B domain variants, p.D963N, p.S806T, p.G873D, p.H998Q and p.Q1225R may be considered as polymorphism or non-pathologic mutations in patients with Haemophilia A.

  6. In this meta-analysis, we have assessed the association between the FXIII-A Val34Leu polymorphism and intracerebral hemorrhage risk. The results of a combined analysis showed no significant association between the FXIII-A Val34Leu polymorphism and ICH (Montrer COL4a2 Kits ELISA) risk in the overall population. The results of this meta-analysis suggest that the FXIII-A Val34Leu polymorphism is not associated with ICH (Montrer COL4a2 Kits ELISA) risk in a Caucasian population.

  7. von Willebrand factor (Montrer VWF Kits ELISA) binds to the surface of dendritic cells and modulates peptide presentation of factor VIII.

  8. Desmopressin acetate increases F8 plasma concentration in patients with combined deficiency of factors V and VIII (Montrer COX8A Kits ELISA).

  9. 37 (70%) of the 53 had discordant antigen-activity ratio, majority of those mutations produced FVIII with low FVIII-specific activity. However, 4 (7.5%) of the 53 mutations produced higher specific activity of FVIII. It is possible that these mutations either produce a secretory defect or an increased metabolic turnover to account for the low levels of FVIII with these mutations.

  10. Platelet-targeted FVIII gene therapy has higher therapeutic efficacy compared to factor VIII replacement therapy may be due to accelerated thrombin (Montrer F2 Kits ELISA) generation.

Pig (Porcine) Coagulation Factor VIII (F8) interaction partners

  1. thrombin (Montrer F2 Kits ELISA) stimulates transglutaminase activity in articular cartilage by directly cleaving factor XIII (Montrer UGDH Kits ELISA) and by receptor-mediated up-regulation of factor XIII (Montrer UGDH Kits ELISA) synthesis

  2. cupredoxin-like A1 subdomains in fVIII contain inter-species differences that are a result of selective pressure on the dissociation rate constant

Cow (Bovine) Coagulation Factor VIII (F8) interaction partners

  1. Factor VIIIc (Montrer COX7A2 Kits ELISA) is responsible for tissue invasion during tumor progression.

Factor VIII (F8) profil antigène

Antigen Summary

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

Gene names and symbols associated with Coagulation Factor VIII (F8) Kits ELISA

  • coagulation factor VIIi (f7i) anticorps
  • coagulation factor VIII (F8) anticorps
  • coagulation factor VIII, procoagulant component (F8) anticorps
  • AHF anticorps
  • Cf-8 anticorps
  • Cf8 anticorps
  • DXS1253E anticorps
  • F8B anticorps
  • F8C anticorps
  • fb61d02 anticorps
  • FVIII anticorps
  • HEMA anticorps
  • wu:fb61d02 anticorps

Protein level used designations for Coagulation Factor VIII (F8) Kits ELISA

Factor VIII , procoagulant component , antihemophilic factor , coagulation factor VIII , coagulation factor VIIIc , factor VIII F8B , coagulation factor VIII, procoagulant component (hemophilia A) , factor VIII , coagulation co-factor

GENE ID SPECIES
282671 Danio rerio
14069 Mus musculus
2157 Homo sapiens
397339 Sus scrofa
403875 Canis lupus familiaris
100271720 Bos taurus
100303761 Oryctolagus cuniculus
302470 Rattus norvegicus
100359363 Ovis aries
422199 Gallus gallus
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