Collagen, Type VIII, alpha 1 (COL8A1) Kits ELISA

COL8A1 encodes one of the two alpha chains of type VIII collagen. De plus, nous expédions COL8A1 Anticorps (56) et COL8A1 Protéines (12) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
COL8A1 12837 Q00780
COL8A1 304021  
COL8A1 1295 P27658
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Showing 10 out of 25 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 0.065 ng/mL 0.15-10 ng/mL 96 Tests Connectez-vous pour afficher 11 to 15 Days
592,59 €
Détails
Souris 0.16 ng/mL 40-0.63 ng/mL   96 Tests Connectez-vous pour afficher 13 to 17 Days
772,39 €
Détails
Poulet 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
666,67 €
Détails
Cobaye 46.875 pg/mL 78.125-5000 pg/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
666,67 €
Détails
Lapin 37.5 pg/mL 62.5-4000 pg/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
666,67 €
Détails
Rat 1.0 pg/mL 225-500 pg/mL   96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
Détails
Singe 1.0 pg/mL 225-500 pg/mL   96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
Détails
Chien 1.0 pg/mL 225-500 pg/mL   96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
Détails
Porc
  96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
Détails
Mouton
  96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
Détails

Plus Kits ELISA pour COL8A1 partenaires d'interaction

Mouse (Murine) Collagen, Type VIII, alpha 1 (COL8A1) interaction partners

  1. Lack of collagen VIII (Montrer COX8A Kits ELISA) reduces myofibroblast differentiation and fibrosis and promotes early mortality and left ventricle dilatation in response to pressure overload in mice.

  2. Type VIII (Montrer COX8A Kits ELISA) collagen signals via beta1 integrin and RhoA (Montrer RHOA Kits ELISA) to regulate MMP-2 (Montrer MMP2 Kits ELISA) expression and smooth muscle cell migration.

  3. Type VIII (Montrer COX8A Kits ELISA) collagen mediates vessel wall remodeling after arterial injury and fibrous cap formation in atherosclerosis.

  4. in contrast to diabetic wild-type mice EMT (Montrer ITK Kits ELISA)-like changes were attenuated in diabetic Col8alpha1/alpha2-KO mice, indicating that collagen VIII (Montrer COX8A Kits ELISA) may be 1 of the major inducers of epithelial-to-mesenchymal transition-like changes in kidneys of diabetic wild-type mice

  5. Type VIII (Montrer COX8A Kits ELISA) collagen significantly modulates the effect of TGF-beta1 (Montrer TGFB1 Kits ELISA) on mesangial cells and may therefore play a role in the pathogenesis of diabetic nephropathy.

  6. Crystal structure of mouse alpha1(VIII (Montrer COX8A Kits ELISA))(3) NC1 domain trimer at 1.9 A resolution. Surface of collagen VIII (Montrer COX8A Kits ELISA) NC1 trimer has three strips of partially exposed aromatic residues, likely involved in supramolecular assemblies.

  7. These data indicate that type VIII (Montrer COX8A Kits ELISA) collagen plays an important role in glial scar formation during the repair process by astrocytes.

  8. Smooth muscle cells can modify the matrix microenvironment by producing type VIII (Montrer COX8A Kits ELISA) collagen, using it to overlay type I collagen, and generating a substrate favorable for migration

  9. Downregulation of COL8A1 expression sensitized hepatocarcinoma cells to the action of D-limonene, impeded cell proliferation, and led to decreased invasiveness, indicating that COL8A1 might serve as a target for gene therapy in hepatocarcinoma.

  10. Oxidized phospholipids induce type VIII (Montrer COX8A Kits ELISA) collagen expression and vascular smooth muscle cell migration.

Human Collagen, Type VIII, alpha 1 (COL8A1) interaction partners

  1. High COL8A1 level is associated with chronic obstructive pulmonary disease and cancer.

  2. The COL8A1 rs13095226 polymorphism is not associated with nAMD or PCV, which suggesting this gene maybe not a susceptibility gene locus for neovascular age-related macular degeneration (nAMD) or polypoidal choroidal vasculopathy (PCV) in Chinese subjects.

  3. High COL8A1 expression is associated with early loss of kidney function.

  4. Data indicate that complement factor H (CFH (Montrer CFH Kits ELISA)) R1210C and common variants in COL8A1 and RAD51B plus six genes contribute predictive information for advanced macular degeneration (AMD (Montrer AMD1 Kits ELISA)) beyond macular and behavioral phenotypes.

  5. The results are consistent with the proposal that rare CNVs play a role in TS aetiology and suggest a possible role for rearrangements in the COL8A1 and NRXN1 (Montrer NRXN1 Kits ELISA) gene regions.

  6. In addition, eight genes classified as 'second tier' hits in the original study (PAX7 (Montrer PAX7 Kits ELISA), THADA, COL8A1/FILIP1L, DCAF4L2, GADD45G (Montrer GADD45G Kits ELISA), NTN1 (Montrer NTN1 Kits ELISA), RBFOX3 (Montrer RBFOX3 Kits ELISA) and FOXE1 (Montrer FOXE1 Kits ELISA)) showed evidence of linkage and association in this replication sample.

  7. The purpose of this study is to evaluate COL8A1 and COL8A2 (Montrer COL8a2 Kits ELISA) as candidate genes for thin central corneal thickness in human primary open angle glaucoma patients.

  8. The absence of pathogenic mutations identified in the COL8A1 or COL8A2 (Montrer COL8a2 Kits ELISA) genes in affected members of 15 pedigrees with familial FECD (Montrer COL8a2 Kits ELISA) (Fuchs endothelial corneal dystrophy) indicates that other genetic factors are involved.

  9. The absence of pathogenic mutations in COL8A1 and COL8A2 (Montrer COL8a2 Kits ELISA) in patients with keratoconus indicates that other genetic factors are involved in the pathogenesis of this corneal ectatic disorder.

COL8A1 profil antigène

Antigen Summary

This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same protein have been observed.

Gene names and symbols associated with COL8A1

  • collagen, type VIII, alpha 1 (COL8A1) anticorps
  • collagen, type VIII, alpha 1 (col8a1) anticorps
  • collagen, type VIII, alpha 1 (Col8a1) anticorps
  • C3orf7 anticorps
  • Col8a-1 anticorps
  • COL8A1 anticorps

Protein level used designations for COL8A1

collagen, type VIII, alpha 1 , collagen alpha-1(VIII) chain , procollagen type VIII alpha 1 , procollagen, type VIII, alpha 1 , cell proliferation-inducing protein 41 , collagen VIII, alpha-1 polypeptide , endothelial collagen , smooth muscle cell-expressed and macrophage conditioned medium-induced protein smag-64 , alpha 1 type VIII collagen , collagen VIII , type VIII collagen alpha 1 chain

GENE ID SPECIES
460550 Pan troglodytes
494652 Xenopus laevis
100017530 Monodelphis domestica
100585226 Nomascus leucogenys
12837 Mus musculus
304021 Rattus norvegicus
1295 Homo sapiens
100009383 Oryctolagus cuniculus
100717829 Cavia porcellus
397430 Sus scrofa
418378 Gallus gallus
487950 Canis lupus familiaris
538564 Bos taurus
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