anti-DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) Anticorps

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. De plus, nous expédions DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DCLRE1B 64858 Q9H816
DCLRE1B 310745 Q4KLY6
DCLRE1B 140917 Q8C7W7
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Top anti-DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Anticorps sur anticorps-enligne.fr

Showing 10 out of 30 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IHC (p), WB DCLRE1B Antibody (Center)(ABIN651618) western blot analysis in mouse kidney tissue lysates (35 µg/lane). This demonstrates the DCLRE1B antibody detected DCLRE1B protein (arrow). DCLRE1B Antibody (Center) (ABIN651618) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Souris Inconjugué FACS, IHC, WB HEK293T cells transfected with either RC205744 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-DCLRE1B antibody (ABIN2454181), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DCLRE1B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-DCLRE1B. 100 μL Connectez-vous pour afficher 6 to 8 Days
418,10 €
Détails
Humain Lapin Inconjugué ELISA, WB 100 μL Connectez-vous pour afficher 13 Days
154,33 €
Détails
Humain Lapin Inconjugué WB Western blot analysis of DCLRE1B expression in HOS (A) whole cell lysates. 200 μL Connectez-vous pour afficher 11 to 13 Days
464,29 €
Détails
Humain Souris Inconjugué FACS, IHC, IHC (p), WB Immunohistochemistry-Paraffin: DCLRE1B Antibody (2B7) [NBP2-03563] Staining of paraffin-embedded Human endometrium tissue using anti-DCLRE1B mouse monoclonal antibody. Western Blot: DCLRE1B Antibody (2B7) [NBP2-03563] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DCLRE1B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DCLRE1B. 0.1 mL Connectez-vous pour afficher 4 to 7 Days
426,25 €
Détails
Humain Souris Inconjugué FACS, IHC (p), WB   100 μL Connectez-vous pour afficher 11 to 14 Days
626,83 €
Détails
Humain Lapin Inconjugué WB Western blot analysis of extracts of THP-1 cells, using DCLRE1B antibody. 100 μL Connectez-vous pour afficher 12 Days
392,86 €
Détails
Humain Lapin Inconjugué ICC, IF Immunocytochemistry/Immunofluorescence: DCLRE1B Antibody  - Staining of human cell line RH-30 shows localization to nucleoplasm & nuclear bodies. 100 μL Connectez-vous pour afficher 6 to 9 Days
418,75 €
Détails
Humain Lapin Inconjugué IHC (p), WB   400 μL Connectez-vous pour afficher 6 to 8 Days
538,22 €
Détails
Humain Lapin Inconjugué ELISA, IHC, WB   200 μL Connectez-vous pour afficher 11 to 14 Days
845,08 €
Détails

DCLRE1B Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) Anticorps mieux référencés

  1. Human Polyclonal DCLRE1B Primary Antibody pour IHC (p), WB - ABIN651618 : Bae, Mukhopadhyay, Liu, Zhang, Tan, Akhter, Liu, Shen, Li, Legerski: Snm1B/Apollo mediates replication fork collapse and S Phase checkpoint activation in response to DNA interstrand cross-links. dans Oncogene 2008 (PubMed)
    Show all 4 references for 651618

Plus d’anticorps contre DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) partenaires d’interaction

Human DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) interaction partners

  1. Different charge distributions along the DNA binding groove may account for the drastic difference in processivity and DNA digestion efficiency, including that of damaged substrates, between SNM1A (Montrer DCLRE1A Anticorps) and SNM1B.

  2. The SNM1B/APOLLO DNA nuclease (Montrer DCLRE1C Anticorps) functions in resolution of replication stress and maintenance of common fragile site stability.

  3. the N-terminal region of Snm1B forms a complex containing PSF2 (Montrer TAP2 Anticorps) and Mus81 (Montrer MUS81 Anticorps), while the C-terminal region is important for PSF2 (Montrer TAP2 Anticorps)-mediated chromatin association.

  4. The nuclease (Montrer DCLRE1C Anticorps) hSNM1B/Apollo is linked to the Fanconi anemia (Montrer PALB2 Anticorps) pathway via its interaction with FANCP/SLX4 (Montrer BTBD12 Anticorps).

  5. differences in the substrate selectivities of SNM1A (Montrer DCLRE1A Anticorps) and SNM1B are likely to be relevant to their in vivo roles

  6. SNM1B functions epistatically to the central Fanconi anemia (Montrer PALB2 Anticorps) factor, FANCD2 (Montrer FANCD2 Anticorps), in cellular survival after interstrand crosslinks damage and homology-directed repair of DNA double-strand breaks

  7. TRF2 (Montrer TERF2 Anticorps), which binds preferentially to positively supercoiled DNA substrates, together with Apollo, negatively regulates the amount of TOP1 (Montrer TOP1 Anticorps), TOP2alpha, and TOP2beta (Montrer TOP2B Anticorps) at telomeres.

  8. siRNA knockdown of hSNM1B rendered cells sensitive to ionizing radiation, suggesting the possibility of hSNM1B involvement in homologous recombination repair of double-strand breaks arising as intermediates of ICL repair

  9. the C terminus of Snm1B was shown to interact with the TRF (Montrer IL5 Anticorps) homology domain of TRF2 (Montrer TERF2 Anticorps) indicating that Snm1B is likely recruited to the telomere via interaction with the double-stranded telomere-binding protein TRF2 (Montrer TERF2 Anticorps)

  10. SNM1B (Apollo) protein exhibits a 5'-to-3' DNA exonuclease (Montrer EXO1 Anticorps) activity and functions together with TRF2 (Montrer TERF2 Anticorps) to protect telomeres from damage and fusion.

Mouse (Murine) DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) interaction partners

  1. Study documents the combinatorial action of Apollo, POT1b, CST (Montrer CORT Anticorps), and the 5' exonuclease (Montrer EXO1 Anticorps) Exo1 (Montrer EXO1 Anticorps) in postreplicative telomere end processing in mouse cells, clarifying the mechanism by which the telomeric 3' overhang is generated and modulated.

  2. The telomeric protein (Montrer SYCE1 Anticorps) SNM1B/Apollo is required for normal cell proliferation and embryonic development

  3. TRF2 (Montrer TERF2 Anticorps)-bound Apollo functions at replicating telomeres, promoting the maintenance of the telomeric overhang, repressing S phase-specific ATM (Montrer ATM Anticorps) signaling, and protecting leading-end telomeres from fusion.

  4. Apollo null mouse embryo fibroblasts exhibit an increased incidence of G2 chromatid-type fusions involving telomeres created by leading-strand DNA synthesis, reflective of a failure to protect these telomeres after DNA replication.

DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) profil antigène

Profil protéine

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000

Gene names and symbols associated with DCLRE1B

  • DNA cross-link repair 1B (DCLRE1B) anticorps
  • DNA cross-link repair 1B (Dclre1b) anticorps
  • DNA cross-link repair 1B (dclre1b) anticorps
  • DNA cross-link repair 1B, PSO2 homolog (S. cerevisiae) (Dclre1b) anticorps
  • AI452214 anticorps
  • Apollo anticorps
  • im:6894074 anticorps
  • mSNM1B anticorps
  • SNM1B anticorps
  • SNMIB anticorps
  • zgc:154089 anticorps

Protein level used designations for DCLRE1B

5' exonuclease Apollo , DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae) , PSO2 homolog , SNM1 homolog B , DNA cross-link repair 1B protein

GENE ID SPECIES
64858 Homo sapiens
428269 Gallus gallus
310745 Rattus norvegicus
768137 Danio rerio
140917 Mus musculus
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