anti-Doublecortin (DCX) Anticorps

DCX encodes a member of the doublecortin family. De plus, nous expédions Doublecortin Kits (38) et Doublecortin Protéines (12) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DCX 1641 O43602
DCX 13193 O88809
DCX 84394  
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Showing 10 out of 167 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB <b>WB Suggested Anti-DCX Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
Chien Lapin Inconjugué WB <b>WB Suggested Anti-DCX Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>293T cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of anti-DCX Antibody (S128) (ABIN389254) in K562 cell line lysates (35 µg/lane). DCX (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with DCX Antibody (S128) (ABIN389254), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 10 to 11 Days
Humain Lapin Inconjugué EIA, IHC (p), WB 0.4 mL Connectez-vous pour afficher 6 to 8 Days
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from RAW264.7 cells, using Doublecortin (Ab-297) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
Souris Lapin Inconjugué WB   100 μg Connectez-vous pour afficher 4 to 6 Days
Humain Souris Inconjugué WB Western Blot analysis of DCX expression in transfected 293T cell line by DCX monoclonal antibody (M01), clone 1G12. Lane 1: DCX transfected lysate(41.4 KDa). Lane 2: Non-transfected lysate. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
Humain Souris Inconjugué ICC, FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of SK-N-SH cells using DCX mouse mAb (green) and negative control (red) . 0.1 mg Connectez-vous pour afficher 2 to 3 Days
Souris Souris Inconjugué IF, WB Western blot analysis of Doublecortin on a mouse neonate lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-mouse Doublecortin antibody. 50 μg Connectez-vous pour afficher 6 to 8 Days
Humain Lapin Inconjugué IHC (p), WB 0.1 mg Connectez-vous pour afficher 6 to 8 Days

DCX Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Doublecortin Anticorps mieux référencés

  1. Mouse (Murine) Monoclonal Doublecortin Primary Antibody pour IF, WB - ABIN968637 : des Portes, Pinard, Billuart, Vinet, Koulakoff, Carrié, Gelot, Dupuis, Motte, Berwald-Netter, Catala, Kahn, Beldjord, Chelly: A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome. dans Cell 1998 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal Doublecortin Primary Antibody pour IF, ELISA - ABIN560579 : Jiang, Brackeva, Stangé, Verhaeghen, Costa, Couillard-Després, Rotheneichner, Aigner, Van Schravendijk, Pipeleers, Ling, Gorus, Martens: LC-MS/MS identification of doublecortin as abundant beta cell-selective protein discharged by damaged beta cells in vitro. dans Journal of proteomics 2013 (PubMed)

  3. Human Monoclonal Doublecortin Primary Antibody pour ICC, FACS - ABIN969513 : Evangelisti, Florian, Massimi, Dominici, Giannini, Galardi, Buè, Massalini, McDowell, Messi, Gulino, Farace, Ciafrè: MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness. dans FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009 (PubMed)

  4. Mouse (Murine) Polyclonal Doublecortin Primary Antibody pour ELISA, WB - ABIN4305985 : Klempin, Kronenberg, Cheung, Kettenmann, Kempermann: Properties of doublecortin-(DCX)-expressing cells in the piriform cortex compared to the neurogenic dentate gyrus of adult mice. dans PLoS ONE 2011 (PubMed)

Plus d’anticorps contre Doublecortin partenaires d’interaction

Human Doublecortin (DCX) interaction partners

  1. this suggests that the microtubule-interacting doublecortin domain observed in cryo-electron micrographs is the C-terminal domain rather than the N-terminal one.

  2. From this family, we conclude that a DCX mutation causes a pleiotropic phenotype in the female even if X chromosome inactivation pattern is not skewed, and the novel missense mutation in DCX produced relatively mild dysfunction of the doublecortin protein.

  3. We identified a novel DCX mutation c.785A > G, p.Asp262Gly in a family with X-linked lissencephaly and subcortical band heterotopia

  4. In high-risk metastatic Neuroblastoma (Montrer ARHGEF16 Anticorps), TH and DCX mRNA quantification could be used for the assessment of response to treatment and for early detection of progressive disease or relapses.

  5. Results point to a critical role of doublecortin in the formation of the neuromuscular junctions.

  6. DCX-positive cells occur in a wide range of hypothalamic nuclei in humans, mice and sheep.

  7. human DCX protein was expressed in human adipose stem cells, collagen II was decreased while aggrecan (Montrer ACAN Anticorps), matrilin 2 (Montrer MATN2 Anticorps), and GDF5 (Montrer GDF5 Anticorps) were increased during the 14-day pellet culture.

  8. We propose that DCDC2 (Montrer DCDC2 Anticorps) is a tumor suppressor gene of HCC (Montrer FAM126A Anticorps).

  9. in utero doublecortin knockdown, but not knockout, shows a neocortical neuronal migration phenotype.

  10. Immunoblots revealed that depressed subjects displayed increased expression of doublecortin.

Mouse (Murine) Doublecortin (DCX) interaction partners

  1. MEIS2 (Montrer MEIS2 Anticorps) associates with chromatin-bound PBX1 (Montrer PBX1 Anticorps), recruits PARP1/ARTD1 (Montrer PARP1 Anticorps), and initiates PARP1 (Montrer PARP1 Anticorps)-mediated eviction of H1 from the chromatin fiber.

  2. The regulation axis from microRNA-128-3p to doublecortin is critical for hippocampus-related contextual learning not only in wild type, but also in mice infused with Abeta (Montrer APP Anticorps)-42.

  3. Findings demonstrate the direct requirement of ADAM10 (Montrer ADAM10 Anticorps) in cortical radial migration and reveal the underlying mechanism by linking ADAM10 (Montrer ADAM10 Anticorps)-initiated regulated intramembrane proteolysis of Notch (Montrer NOTCH1 Anticorps) to the regulation of microtubule cytoskeleton through transcriptional control of Dcx expression

  4. Dcx is a new marker for the Pax7 (Montrer PAX7 Anticorps)(+)MyoD (Montrer MYOD1 Anticorps)(-) subpopulation, which contributes to myofiber maturation during muscle regeneration.

  5. DCX-positive cells resembling immature and developing neurons were found in mice and sheep and human hypothalamus.

  6. we showed that miR (Montrer MLXIP Anticorps)-29a directly regulated its target protein Doublecortin (DCX) expression, which further modulated axon branching in primary culture.

  7. Cdk5 (Montrer CDK5 Anticorps) and its substrates, Dcx and p27kip1 (Montrer CDKN1B Anticorps), regulate cytoplasmic dilation formation and nuclear elongation in migrating neurons.

  8. Doublecortin knockout mice show lamination defects of the hippocampal pyramidal cell layer largely restricted to the CA3 (Montrer CA3 Anticorps) region.

  9. Dcx protein- and mRNA-levels reflected changes in neurogenesis

  10. DCX is dispensable for the development of new neurons in adult mice

Doublecortin (DCX) profil antigène

Profil protéine

This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ('double cortex' syndrome) in females and lissencephaly ('smooth brain' syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Doublecortin (DCX) Anticorps

  • doublecortin (DCX) anticorps
  • doublecortin (Dcx) anticorps
  • 18C15.5 anticorps
  • DBCN anticorps
  • Dbct anticorps
  • DC anticorps
  • DCX anticorps
  • LISX anticorps
  • SCLH anticorps
  • XLIS anticorps

Protein level used designations for anti-Doublecortin (DCX) Anticorps

doublecortex; lissencephaly, X-linked (doublecortin) , doublecortin , doublecortex , doublin , lis-X , lissencephalin-X , neuronal migration protein doublecortin , lissencephaly, X-linked (doublecortin)

100058909 Equus caballus
494212 Felis catus
473733 Pan troglodytes
752002 Taeniopygia guttata
1641 Homo sapiens
13193 Mus musculus
84394 Rattus norvegicus
374242 Gallus gallus
787968 Bos taurus
612950 Canis lupus familiaris
100713827 Cavia porcellus
101109861 Ovis aries
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