Dual Specificity Phosphatase 1 (DUSP1) Kits ELISA

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. De plus, nous expédions DUSP1 Anticorps (111) et DUSP1 Protéines (5) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
DUSP1 1843 P28562
DUSP1 19252 P28563
DUSP1 114856 Q64623
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 12.2 pg/mL 31.25-2000 pg/mL 96 Tests Connectez-vous pour afficher 11 to 15 Days
592,59 €
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Souris 13.2 pg/mL 31.25-2000 pg/mL   96 Tests Connectez-vous pour afficher 13 to 16 Days
896,09 €
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Poulet
  96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
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Singe
  96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
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Mouton
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673,47 €
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Cobaye
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673,47 €
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Porc
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673,47 €
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Chien
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673,47 €
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Boeuf (Vache)
  96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
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Rat
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Plus Kits ELISA pour DUSP1 partenaires d'interaction

Human Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. The aim of this review is to shed light on the role of four different phosphatases (PTEN, PP2A (Montrer PPP2R4 Kits ELISA), CDC25 (Montrer RASGRF1 Kits ELISA) and DUSP1) in five different solid tumors (breast cancer, lung cancer, pancreatic cancer, prostate cancer and ovarian cancer), in order to better understand the most frequent and aggressive primary cancer of the central nervous system, glioblastoma.

  2. Dual-specific phosphatase (DUSP1) was found to inhibit gallbladder cancer (GBC) cell proliferation, migration and invasion.

  3. The results presented here emphasize the importance of MKP-1 as a mediator of therapeutic effects of glucocorticoids in inflammatory lung diseases as well as its potential as a novel anti-inflammatory drug target.

  4. we show that IL-1 (Montrer IL1A Kits ELISA) induces robust p38a (Montrer MAPK14 Kits ELISA) activation both in the nucleus and in the cytoplasm/membrane.Following stimulation, p38a (Montrer MAPK14 Kits ELISA) activity returns to a basal level in absence of receptor degradation. While nuclear pulse is controlled by MKP1 through a negative feedback to pp38, its basal activity is controlled by both TAB1 (Montrer TAB1 Kits ELISA) and MKP1 through a positive feedback loop.

  5. Our results emphasize the importance of MKP-1 as a potential predictive biomarker for a subset of breast cancer patients with worse outcome and less susceptibility to treatment.

  6. Collectively, these data indicated that DUSP1 may induce the resistance against paclitaxel through the p38 MAPK (Montrer MAPK14 Kits ELISA)-mediated overexpression of p-glycoprotein in human ovarian cancer cells.

  7. silencing of IL1B (Montrer IL1B Kits ELISA) plus dexamethasone-induced DUSP1 significantly reduced IRF1 (Montrer IRF1 Kits ELISA) expression. IL1B (Montrer IL1B Kits ELISA)-induced expression of CXCL10 (Montrer CXCL10 Kits ELISA) was largely insensitive to dexamethasone, whereas other DUSP1-enhanced, IRF1 (Montrer IRF1 Kits ELISA)-dependent mRNAs showed various degrees of repression.

  8. dexamethasone-induced DUSP1 acts via p38 MAPK (Montrer MAPK14 Kits ELISA) to switch on the mRNA destabilizing function of protein-tristetraprolin (Montrer ZFP36 Kits ELISA) to repress pro-inflammatory cytokine secretion from ASM (Montrer SMPD1 Kits ELISA) cells

  9. LPS (Montrer IRF6 Kits ELISA) tolerance interferes with TLR4 (Montrer TLR4 Kits ELISA) signaling by inhibiting Lyn (Montrer LYN Kits ELISA) and c-Src (Montrer SRC Kits ELISA) phosphorylation and their recruitment to TLR4 (Montrer TLR4 Kits ELISA), while increasing the phosphatase activity and expression of PP2A (Montrer PPP2R4 Kits ELISA), PTPN22 (Montrer PTPN22 Kits ELISA), PTP1B (Montrer PTPN1 Kits ELISA) and MKP1.

  10. This study shows that RIG-I (Montrer DDX58 Kits ELISA) activation results in MKP-1-mediated inhibition of cell proliferation in melanoma cells via controlling the p38 (Montrer CRK Kits ELISA)-HSP27 (Montrer HSPB1 Kits ELISA), c-Jun (Montrer JUN Kits ELISA) and rpS6 (Montrer RPS6 Kits ELISA) pathways

Mouse (Murine) Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. c-FOS and DUSP1 expression levels determine the threshold of tyrosine kinase (Montrer TYRO3 Kits ELISA) inhibitor (TKI) efficacy, such that growth-factor-induced expression of c-FOS and DUSP1 confers intrinsic resistance to TKI therapy in a wide-ranging set of leukemias.

  2. PTHrP (Montrer PTHLH Kits ELISA) counteracts the pro-apoptotic actions of reactive oxygen species by a mechanism dependent on MKP1-induced dephosphorylation.

  3. A2AR (Montrer ADORA2A Kits ELISA) signaling regulates both basal and LPS (Montrer TLR4 Kits ELISA)-induced DUSP1 levels in macrophages via activating the adenylate cyclase pathway.

  4. these data suggest an important role for DUSPs in regulating MAPK (Montrer MAPK1 Kits ELISA) dephosphorylation, with an emphasis on DUSP1, during early adipogenesis

  5. Loss of DUSP1 does not cause changes in cartilage degeneration and gait in a mouse model of spontaneous osteoarthritis at 21 months of age.

  6. Nr4a1 (Montrer NR4A1 Kits ELISA) induction is dependent on ERK1/2 (Montrer MAPK1/3 Kits ELISA) and that MKP-1 negatively regulates this induction.

  7. MKP-1 negatively regulates chemokine (Montrer CCL1 Kits ELISA)-driven osteoclast formation and subsequent bone resorption in response to LPS (Montrer TLR4 Kits ELISA) stimulation

  8. results suggest that the p38alpha (Montrer MAPK14 Kits ELISA)-MKP-1 signaling axis links IL-17R signaling in tissue-resident cells to autoimmune inflammation dependent on infiltrating T(H)17 cells.

  9. DUSP1 and tristetraprolin (Montrer ZFP36 Kits ELISA) cooperate to regulate macrophage responses to lipopolysaccharide.

  10. MKP-1 regulated the expression of MMP-12 (Montrer MMP12 Kits ELISA).

Cow (Bovine) Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. MKP-1 is the specific phosphatase induced by AngII and involved in the negative feedback mechanism ensuring adequate ERK1/2 (Montrer MAPK1/3 Kits ELISA)-mediated aldosterone production in response to the hormone.

Pig (Porcine) Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. Agonist stimulation of vascular smooth muscle increases PKC (Montrer FYN Kits ELISA) activity, which, in turn, increases MKP-1 activity and maintains MAPK1 (Montrer MAPK1 Kits ELISA) activity at submaximal values.

DUSP1 profil antigène

Antigen Summary

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.

Gene names and symbols associated with DUSP1

  • dual specificity phosphatase 1 (DUSP1) anticorps
  • dual specificity phosphatase 1 (dusp1) anticorps
  • dual specificity phosphatase 1 (Dusp1) anticorps
  • 3CH134 anticorps
  • cb269 anticorps
  • CL100 anticorps
  • DUSP1 anticorps
  • erp anticorps
  • HVH1 anticorps
  • id:ibd2586 anticorps
  • mkp-1 anticorps
  • Mkp1 anticorps
  • PTPN10 anticorps
  • Ptpn16 anticorps
  • sb:cb269 anticorps
  • U19515 anticorps
  • wu:fd19g02 anticorps
  • wu:fe50g09 anticorps
  • zgc:55920 anticorps

Protein level used designations for DUSP1

dual specificity protein phosphatase 1 , dual specificity phosphatase 1 , mkp-1 , MAP kinase phosphatase 1 , dual specificity protein phosphatase hVH1 , mitogen-activated protein kinase phosphatase 1 , protein-tyrosine phosphatase CL100 , serine/threonine specific protein phosphatase , mitogen-activated protein kinase phosphatase-1 , protein tyrosine phosphatase, non-receptor type 16 , protein-tyrosine phosphatase 3CH134 , protein-tyrosine phosphatase ERP , 3CH134/CL100 PTPase , MAP kinase phosphatase-1 , mitogen-activated protein (MAP) kinase phosphatase-1 , oxidative stress-inducible protein tyrosine phosphatase , protein tyrosine phosphatase non-receptor type 16 , protein-tyrosine phosphatase non-receptor type 16 , MAPK phosphatase 1

GENE ID SPECIES
374192 Gallus gallus
471742 Pan troglodytes
100219518 Taeniopygia guttata
100340993 Oryctolagus cuniculus
406340 Danio rerio
1843 Homo sapiens
19252 Mus musculus
114856 Rattus norvegicus
489117 Canis lupus familiaris
539175 Bos taurus
100522469 Sus scrofa
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