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ERLIN2 encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. De plus, nous expédions ERLIN2 Protéines (12) et ERLIN2 Kits (11) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal ERLIN2 Primary Antibody pour ELISA, WB - ABIN250539
Pearce, Wang, Kelley, Wojcikiewicz: SPFH2 mediates the endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors and other substrates in mammalian cells. dans The Journal of biological chemistry 2007
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Human Polyclonal ERLIN2 Primary Antibody pour ICC, IF - ABIN4355640
Holland, Burleigh, Git, Goldgraben, Perez-Mancera, Chin, Hurtado, Bruna, Ali, Greenwood, Dunning, Samarajiwa, Menon, Rueda, Lynch, McKinney, Ellis, Eaves, Carroll, Curtis, Aparicio, Caldas: ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium. dans EMBO molecular medicine 2011
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Human Polyclonal ERLIN2 Primary Antibody pour WB - ABIN2787692
Zhang, Yao, Yu, Ni, Zhang, Wang, Lai: Effects of 1.8 GHz radiofrequency radiation on protein expression in human lens epithelial cells. dans Human & experimental toxicology 2013
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swine erlin2 gene has a closer genetic relationship with the erlin2 genes of human and rhesus monkey. This gene is differentially expressed in the liver tissues from Meishan and Large White pigs.
Novel Mutations in Endoplasmic Reticulum Lipid Raft-associated Protein 2 Gene Cause Pure Hereditary Spastic Paraplegia Type 18
Here we show that the multimeric ER proteins erlins-1 and -2 are additional sterol regulatory element binding protein (Montrer CNBP Anticorps) regulators.
ERLIN2 was found to be responsible for causing hereditary spastic paraplegia in a Saudi family.
ERLIN2 may confer a selective growth advantage for breast cancer cells by facilitating a cytoprotective response to various cellular stresses associated with oncogenesis.
ERLIN2 loss on cell growth may advance understanding of the mechanism behind motor neuron degeneration (Montrer CLN8 Anticorps) in primary lateral sclerosis
a novel brain gamma-secretase associated protein , erlin-2, that resides in detergent resistant membranes and affects amyloid beta-peptide production.
a novel role for ERLIN2 in supporting cancer cell growth by promoting the activation of the key lipogenic regulator SREBP1c (Montrer SREBF1 Anticorps) and the production of cytosolic lipid droplets.
study describes an extended consanguineous Saudi family in which hereditary spastic paraplegia is linked to SPG18, an autosomal recessive locus, and show it is associated with a nullimorphic deletion of ERLIN2
Erlin-1 (Montrer ERLIN1 Anticorps) and erlin-2 are novel members of the prohibitin (Montrer PHB Anticorps) family of proteins that define lipid-raft-like domains of the ER.
SPFH2 as a key endoplasmic reticulum associated degradation pathway component and suggest that it may act as a substrate recognition factor.
2 MDa erlin1 (Montrer ERLIN1 Anticorps)/2 complex is composed of an assemblage of lower-order hetero-oligomers, probably heterotrimers, linked together by assembly domain hydrophobic residues.
This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
, ER lipid raft associated 2
, SPFH domain family, member 2
, endoplasmic reticulum lipid raft-associated protein 2
, stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2
, SPFH domain-containing protein 2