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The protein encoded by EGR1 belongs to the EGR family of C2H2-type zinc-finger proteins. De plus, nous expédions EGR1 Kits (41) et EGR1 Protéines (19) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 134 products:
Cow (Bovine) Polyclonal EGR1 Primary Antibody pour IHC, WB - ABIN2779517
Yu, de Belle, Liang, Adamson: Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses. dans Molecular cell 2004
Show all 7 references for ABIN2779517
Human Monoclonal EGR1 Primary Antibody pour IF, WB - ABIN393945
Kim, Jeong, Jeong, Kim, Lee, Shin, Kye, Son: Cigarette smoke-induced Egr-1 represses T beta R-II expression in human skin dermal fibroblasts. dans Toxicology 2010
Show all 5 references for ABIN393945
Human Monoclonal EGR1 Primary Antibody pour WB - ABIN394244
Xu, Toure, Qu, Lin, Song, Shen, Rosario, Garcia, Schmidt, Yan: Advanced glycation end product (AGE)-receptor for AGE (RAGE) signaling and up-regulation of Egr-1 in hypoxic macrophages. dans The Journal of biological chemistry 2010
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Chimpanzee Polyclonal EGR1 Primary Antibody pour EIA, IHC (p) - ABIN401280
Suggs, Katzowitz, Tsai-Morris, Sukhatme: cDNA sequence of the human cellular early growth response gene Egr-1. dans Nucleic acids research 1990
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Human Monoclonal EGR1 Primary Antibody pour ELISA, WB - ABIN969092
Chan, Lee, Ho, Wong, Lam, Tang, Chan, Abdullah, Wong, Lam: High-level expression of early growth response-1 and association of polymorphism with total IgE and atopy in allergic rhinitis adults. dans Clinica chimica acta; international journal of clinical chemistry 2009
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Human Polyclonal EGR1 Primary Antibody pour FACS, IF - ABIN389442
Zhang, Chen, Wang, Guang, Han, Zhang, Tan, Gu: EGR1 decreases the malignancy of human non-small cell lung carcinoma by regulating KRT18 expression. dans Scientific reports 2014
Show all 2 references for ABIN389442
Cow (Bovine) Polyclonal EGR1 Primary Antibody pour IHC, WB - ABIN2779828
Schnell, Zoller, Patel, Williams, Kersh: Early growth response gene 1 provides negative feedback to inhibit entry of progenitor cells into the thymus. dans Journal of immunology (Baltimore, Md. : 1950) 2006
Human Polyclonal EGR1 Primary Antibody pour WB - ABIN2774222
Akutagawa, Nishi, Kyo, Terauchi, Yamazawa, Higuma, Inoue, Isaka: Early growth response-1 mediates downregulation of telomerase in cervical cancer. dans Cancer science 2008
Egr-1 silencing through intracoronary delivery of a targeting DNAzyme at the time of reperfusion following acute myocardial ischemia decreases myocardial inflammation and apoptosis leading to improved cardiac function.
Intracoronary delivery of DNAzymes targeting human EGR-1 reduces infarct size following myocardial ischaemia reperfusion.
Data suggest that Egr-1 protein levels may be tightly regulated in an attempt to diminish neurotoxicity or to enhance plasticity in newborn animals.
we propose a model whereby high YB-1 levels in some TNBC cells can lead to reduced levels of EGR1, which in turn promotes slow cell cycling and resistance to PTX. Therefore YB-1 and EGR1 levels are biologically linked and may provide a biomarker for TNBC response to PTX.
TRAIL overexpression was co-regulated by Egr1 and Hypoxia response element. TRAIL might promote hypoxic A549 cell radiosensitivity and induce apoptosis depending on DR5 (Montrer TNFRSF10B Anticorps) to caspase-3 (Montrer CASP3 Anticorps) pathways.
These results suggest that frameshift mutations of EGR1 and BRSK1 (Montrer BRSK1 Anticorps) might play a role in tumorigenesis through tumor suppressor gene inactivation in colorectal cancer and gastric cancer.
Pulmonary vascular Egr-1 expression is significantly increased in patients with PAH, appears specifically associated with neointimal-type vascular remodeling, and correlates with disease progression.
GRK2 (Montrer ADRBK1 Anticorps) may inhibit IGF1 (Montrer IGF1 Anticorps)-induced human hepatocellular carcinoma cell growth and migration through downregulation of EGR1.
did not find positive association signals of the four single nucleotide polymorphisms in the LAMA2 (Montrer LAMA2 Anticorps) and EGR1 genes with high myopia
In nucleus pulposus cells early transcriptional programming initiated by EGR1 is essentially restrained by the cells' epigenome as it was determined during development and differentiation.
in primary cultures of glioma stemlike cells that EGR1 contributes to stemness marker expression and proliferation by orchestrating a PDGFA (Montrer PDGFA Anticorps)-dependent growth-stimulatory loop.
The Egr-1 and Atg16L1 (Montrer ATG16L1 Anticorps) genes' polymorphisms were significant risk factors for susceptibility to chronic obstructive pulmonary disease (COPD (Montrer ARCN1 Anticorps)) . These results demonstrate that autophagy regulator genetic mutations are associated with COPD (Montrer ARCN1 Anticorps) in male smokers.
IL-33 (Montrer IL33 Anticorps)-ERK (Montrer EPHB2 Anticorps)/JNK (Montrer MAPK8 Anticorps)/p38 (Montrer CRK Anticorps)/Egr-1/TSLP (Montrer TSLP Anticorps) axis involved in allergic skin Th2 inflammation
Chronic hypoxia induces Egr-1 via activation of ERK1/2 (Montrer MAPK1/3 Anticorps) and contributes to pulmonary vascular remodeling.
The authors conclude that Egr-1 protein expression is very sensitive to upregulation by hypoxia in pulmonary artery adventitial fibroblasts and that it plays an important role in the autonomous growth phenotype induced by hypoxia in these cells.
EGR-1's expression prior to ovulation and its stimulating effect on the expression of genes known to be involved in prostaglandin biosynthesis pathway, suggest its potential involvement in the regulation of preovulatory events in cattle.
EGR1, an early growth response factor, is a critical transcription factor that regulates the hepatic clock circuit.
EGR1(-/-) mouse embryonic fibroblasts demonstrated lower susceptibility to Venezuelan equine encephalitis virus-induced cell death than isogenic wild-type fibroblasts, indicating that EGR1 modulates proapoptotic pathways following virus infection.
The levels of B23 (Montrer NPM1 Anticorps) expression are directly regulated by EGR1.
our data demonstrate that the effect of FGF23 (Montrer FGF23 Anticorps) on Pi homeostasis is mediated, at least in part, by activation of egr-1.
associated with this behavior, that is, an increase in the expression of the immediate early (Montrer JUN Anticorps) gene Early Growth Response protein 1 (EGR1, Zif268)
Egr-1 is involved in NMDAR (Montrer GRIN1 Anticorps)-mediated PSD-95 (Montrer DLG4 Anticorps) down-regulation and AMPAR endocytosis, a process important in the expression of long term depression
ERG1 (Montrer KCNH2 Anticorps) overexpression led to the development of highly aggressive B-cell malignancies.
EGR-1-induced GGPPS (Montrer GGPS1 Anticorps) plays a vital role in the liver regeneration through the RAS/MAPK (Montrer MAPK1 Anticorps) signaling.
Egr1 plays an important role in ischemia-reperfusion injury in lung transplants by regulating polymorphonuclear neutrophil infiltration.
Study indicated that ischemia-induced EGR1 expression may exaggerate brain injury by reducing BDNF (Montrer BDNF Anticorps) expression
egr1 colocalizes with tyrosine hydroxylase (Montrer TH Anticorps) in the olfactory bulb throughout brain development.
successive induction of the transcription factors Runx3, Egr1 and Sox9b constitutes a regulatory cascade that controls expression of Follistatin A in pharyngeal endoderm, the latter modulating BMP signaling in developing cranial cartilage in zebrafish
The cDNA coding for zebrafish Egr1 was obtained and its expression pattern was examined during zebrafish embryogenesis using whole-mount in situ hybridization
Egr1 gene has important role in zebrafish embryonic oculogenesis. Lens and retina with egr1 gene deletion were primitive and lacked differentiation. Such arrested retinal and lenticular development in Egr1 morphants resulted in microphthalmos.
Gene therapy using in vivo transfection of an Egr-1 decoy ODN significantly inhibits proliferation of VSMC and intimal hyperplasia of vein grafts in a rabbit model.
Results show that EGR1 plays a key role in tendon formation, healing, and repair through BMP12 (Montrer GDF7 Anticorps)/Smad1 (Montrer SMAD1 Anticorps)/5/8 pathway.
Collectively, these results demonstrate that Egr-1 is expressed rapidly upon HSV-1 infection and that this novel induction could be due to the NFsmall ka, CyrillicB/CREB (Montrer CREB1 Anticorps)-mediated transactivation.
The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.
early growth response protein 1(Egr-1, NGFI-A)
, early growth response protein 1 (egr-1)
, early growth response 1
, early growth response protein 1
, nerve growth factor-induced protein A
, transcription factor ETR103
, transcription factor Zif268
, zinc finger protein 225
, zinc finger protein Krox-24
, Krox-24 nuclear protein
, zinc finger protein ZENK
, zinc-finger transcriptional protein
, early growth response protein 1-A