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anti-Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2) Anticorps

EEF1A2 encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. De plus, nous expédions EEF1A2 Protéines (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
EEF1A2 100360150  
EEF1A2 1917 Q05639
EEF1A2 13628 P62631
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Top anti-EEF1A2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 56 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit  <br /> Target Name: EEF1A2  <br /> Sample Tissue: Human Fetal Heart <br /> Antibody Dilution: 1.0 µg/mL 50 μg Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Souris Lapin Inconjugué IHC (p), WB EEF1A2 Antibody (C-term) (ABIN656488) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Connectez-vous pour afficher 6 to 9 Days
335,24 €
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB Formalin fixed and paraffin embedded human brain tissue reacted with EEF1A2 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of EEF1A2 Antibody (C-term) Cat.-No AP51369PU-N in mouse liver tissue lysates (35ug/lane).This demonstrates the EEF1A2 antibody detected the EEF1A2 protein (arrow). 0.4 mL Connectez-vous pour afficher 8 to 10 Days
418,00 €
Détails
Humain Lapin Inconjugué IHC (p), WB Human Brain, cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Brain, cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Connectez-vous pour afficher 8 to 10 Days
517,00 €
Détails
Humain Souris Inconjugué WB EEF1A2 polyclonal antibody (A01), Lot # 070201JCSb Western Blot analysis of EEF1A2 expression in Hela S3 NE . EEF1A2 polyclonal antibody (A01), Lot # 070201JCSb. Western Blot analysis of EEF1A2 expression in human thyroid(diffuse hyperplasia). 50 μL Connectez-vous pour afficher 8 to 9 Days
221,47 €
Détails
Humain Lapin Inconjugué IHC (p), WB IHC-P Image EEF1A2 antibody detects EEF1A2 protein at cytosol on mouse fore brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse fore brain. EEF1A2 antibody , dilution: 1:500. IHC-P Image EEF1A2 antibody detects EEF1A2 protein at cytosol on rat fore brain by immunohistochemical analysis. Sample: Paraffin-embedded rat fore brain. EEF1A2 antibody , dilution: 1:500. 100 μL Connectez-vous pour afficher 5 to 7 Days
357,24 €
Détails
Humain Lapin Inconjugué IHC (p), WB WB Image Sample(30μg whole cell lysate) A: 293T B: A431 , C: H1299 D: HeLa S3 , E: Hep G2 , F: MOLT4 , G: Raji , 10% SDS PAGE antibody diluted at 1:1000 WB Image Sample (50 ug of whole cell lysate) A: mouse brain 10% SDS PAGE antibody diluted at 1:5000 100 μL Connectez-vous pour afficher 5 to 7 Days
357,24 €
Détails
Boeuf (Vache) Chèvre Inconjugué EIA, WB Staining of Jurkat lysate using EEF1A2 Antibody at 0.5 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Staining of Mouse (A+C) and Rat (B+D) Skeletal Muscle (A+B) and Heart (C+D) lysatesusing using EEF1A2 Antibody at 0.5 mg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Connectez-vous pour afficher 8 to 10 Days
374,00 €
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 6 to 8 Days
459,65 €
Détails
Humain Lapin Inconjugué IHC (p), WB Human Brain, cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Brain, cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Connectez-vous pour afficher 11 to 14 Days
501,70 €
Détails

EEF1A2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité
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Human , , , ,
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Mouse (Murine) , , , ,
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anti-EEF1A2 Anticorps mieux référencés

  1. Human Polyclonal EEF1A2 Primary Antibody pour EIA,IHC (p) - ABIN952027 : Lee, Surh: eEF1A2 as a putative oncogene. dans Annals of the New York Academy of Sciences 2009 (PubMed)
    Show all 2 references for ABIN952027

  2. Human Polyclonal EEF1A2 Primary Antibody pour WB,ELISA - ABIN560693 : Scaggiante, Dapas, Bonin, Grassi, Zennaro, Farra, Cristiano, Siracusano, Zanconati, Giansante, Grassi: Dissecting the expression of EEF1A1/2 genes in human prostate cancer cells: the potential of EEF1A2 as a hallmark for prostate transformation and progression. dans British journal of cancer 2012 (PubMed)
    Show all 2 references for ABIN560693

  3. Mouse (Murine) Polyclonal EEF1A2 Primary Antibody pour WB,IHC (p) - ABIN656488 : Yanaka, Kaseda, Tanaka, Nogusa, Sumiyoshi, Kato: Generation of a zinc finger protein ZPR1 mutant that constitutively interacted with translation elongation factor 1alpha. dans Bioscience, biotechnology, and biochemistry 2009 (PubMed)

  4. Cow (Bovine) Polyclonal EEF1A2 Primary Antibody pour WB - ABIN405979 : Grassi, Scaggiante, Farra, Dapas, Agostini, Baiz, Rosso, Tiribelli: The expression levels of the translational factors eEF1A 1/2 correlate with cell growth but not apoptosis in hepatocellular carcinoma cell lines with different differentiation grade. dans Biochimie 2007 (PubMed)

Plus d’anticorps contre EEF1A2 partenaires d’interaction

Human Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2) interaction partners

  1. By directly targeting eEF1A2.

  2. Both eEF1A1 (Montrer EEF1A1 Anticorps) and eEF1A2 colocalise with all eEF1B (Montrer EEF1B2 Anticorps) subunits, in such close proximity that they are highly likely to be in a complex.

  3. De novo EEF1A2 mutations in patients with characteristic facial features, intellectual disability, autistic behaviors and epilepsy.

  4. Finally, a strong association between the expression of EEF1A2, phosphorylated AKT (Montrer AKT1 Anticorps) and MDM4 (Montrer MDM4 Anticorps) was observed in human HCC (Montrer FAM126A Anticorps) samples. Strong activation of the EEF1A2/PI3K (Montrer PIK3CA Anticorps)/AKT (Montrer AKT1 Anticorps)/mTOR (Montrer FRAP1 Anticorps)/MDM4 (Montrer MDM4 Anticorps) signaling pathway was observed in HCC (Montrer FAM126A Anticorps) patients

  5. Overexpression of eEF1A2 was correlated with worse outcomes in gastric cancer patients, suggesting its critical roles in the carcinogenesis of gastric cancer.

  6. miR (Montrer MLXIP Anticorps)-663 and miR (Montrer MLXIP Anticorps)-744 mediate inhibition of the proto-oncogene (Montrer RAB1A Anticorps) eEF1A2 expression that results in retardation of the MCF7 cancer cells proliferation. We also observed upregulation of miR (Montrer MLXIP Anticorps)-663 and miR (Montrer MLXIP Anticorps)-744 with corresponding downregulation of eEF1A2 in resveratrol-treated MCF7 cells, suggesting that resveratrol may influence eEF1A2 expression through a miRNA-dependent pathway.

  7. Our data suggests that eEF1A2 plays an important role in prostate cancer development, especially in inhibiting apoptosis.

  8. The activation level of the EEF1A2/PI3K (Montrer PIK3CA Anticorps)/AKT (Montrer AKT1 Anticorps)/mTOR (Montrer FRAP1 Anticorps)/MDM4 (Montrer MDM4 Anticorps) axis significantly influences the survival probability of hepatocellular carcinoma patients

  9. There was no significant correlation between eEF1A2 protein and mRNA expression levels. Negative immunostaining of eEF1A2 predicted for poor prognosis of NSCLC.

  10. results provide evidence of eEF1A2 as a potential therapeutic target in the treatment of aggressive pancreatic cancer

Rabbit Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2) interaction partners

  1. eEF1A2 crystals obtained using ammonium sulfate as precipitant diffracted to 2.5 A resolution and belonged to space group P6(1)22 or P6(3)22 (unit-cell parameters a = b = 135.4, c = 304.6 A).

Mouse (Murine) Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2) interaction partners

  1. This provides the first in vivo confirmation that eEF1A2 plays an important role in translation.

  2. Heterozygous mutant mice showed no deficit in neuromuscular function or signs of spinal cord pathology, in spite of the low levels of eEF1A2

  3. In-depth analysis using site-directed mutagenesis revealed that PKCbetaI could phosphorylate Ser (Montrer SIGLEC1 Anticorps)(3) of the eEF1A2 isoform and that the association between eEF1A2 and PKCbetaI was dependent on the phosphorylation status of eEF1A2

  4. EEF1A2 may play contribute to the induction or progression of some plasmacytomas and a small percentage of multiple myeloma.

  5. these results suggest an important role for eEF1A2 in driving cap-independent translation of utrophin (Montrer UTRN Anticorps) A in skeletal muscle.

  6. expression of eEF1A-2/S1 protein is activated upon myogenic differentiation

  7. This is a putative oncogene (Montrer RAB1A Anticorps) in ovarian cancer.

  8. Data suggest that spontaneous failure of eEF1A2 expression in the wasted mutant first triggers gliosis in spinal cord and retraction of motor nerve terminals in muscle, and then motor neuron pathology and death.

  9. eEF1A-2 interacts with Prdx-I to functionally provide cells with extraordinary resistance to oxidative stress-induced (Montrer SQSTM1 Anticorps) cell death[eEF1A-2 and Prdx-I]

  10. The above findings suggest that an increase in free-form eEF1A under alkaline conditions plays a critical role in alkalinization-induced cell growth.

EEF1A2 profil antigène

Profil protéine

This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with EEF1A2

  • eukaryotic translation elongation factor 1 alpha 2 (EEF1A2) anticorps
  • eukaryotic translation elongation factor 1 alpha 2 (eef1a2) anticorps
  • eukaryotic translation elongation factor 1 alpha 2 (EEF1) anticorps
  • eukaryotic translation elongation factor 1 alpha 2 (eef1) anticorps
  • eukaryotic translation elongation factor 1 alpha 2 (LOC100360150) anticorps
  • eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) anticorps
  • eukaryotic translation elongation factor 1 alpha 2 (Eef1a2) anticorps
  • Eef1a anticorps
  • EEF1A-2 anticorps
  • EEF1A2 anticorps
  • EEF1AL anticorps
  • EF-1-alpha-2 anticorps
  • EF1A anticorps
  • HS1 anticorps
  • Ps10 anticorps
  • RATPS10 anticorps
  • S1 anticorps
  • STN anticorps
  • Stnl anticorps
  • wasted anticorps
  • wst anticorps
  • zgc:92085 anticorps

Protein level used designations for EEF1A2

eukaryotic translation elongation factor 1 alpha 2 , ef-1-alpha-2 , elongation factor 1-alpha 1 , elongation factor 1-alpha 2 , eEF1A-2 , elongation factor-1 alpha , eukaryotic elongation factor 1 A-2 , statin S1 , statin-S1 , EF-1-alpha-2 , elongation factor 1 A-2 , elongation factor 1 A2 , Statin-like protein

GENE ID SPECIES
419244 Gallus gallus
496898 Xenopus (Silurana) tropicalis
739210 Pan troglodytes
5727887 Chlamydomonas reinhardtii
9620997 Volvox carteri f. nagariensis
100025136 Monodelphis domestica
100360150 Rattus norvegicus
100549386 Meleagris gallopavo
403506 Canis lupus familiaris
436644 Danio rerio
380550 Xenopus laevis
1917 Homo sapiens
515233 Bos taurus
100008677 Oryctolagus cuniculus
13628 Mus musculus
24799 Rattus norvegicus
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