Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5) Kits ELISA

EIF2B5 encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. De plus, nous expédions EIF2B5 Anticorps (31) et EIF2B5 Protéines (4) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
Anti-Souris EIF2B5 EIF2B5 224045 Q8CHW4
Anti-Rat EIF2B5 EIF2B5 192234 Q64350
Anti-Humain EIF2B5 EIF2B5 8893 Q13144
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Plus Kits ELISA pour EIF2B5 partenaires d'interaction

Mouse (Murine) Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5) interaction partners

  1. These results reveal a key role of the AKT (Montrer AKT1 Kits ELISA)-GSK3beta (Montrer GSK3b Kits ELISA)-eIF2Bepsilon signaling module in regulating axon regeneration in the adult mammalian central nervous system.

  2. analysis of eukaryotic initiation factor 2B epsilon phosphorylation sites and ubiquitin-modified lysine residues

  3. Data show that toll (Montrer TLR4 Kits ELISA)-like receptors (TLRs)-TRIF (Montrer RNF138 Kits ELISA) signalling activates eIF2B (Montrer EIF2B4 Kits ELISA) GEF (Montrer ARHGEF2 Kits ELISA) through PP2A-mediated serine dephosphorylation of the eIF2B (Montrer EIF2B4 Kits ELISA) varepsilon-subunit.

  4. mouse model of EIF2B (Montrer EIF2B4 Kits ELISA)-related leukodystrophy; findings provide evidence that hypomorphic Eif2b5 alleles lead to delayed and abnormal development and maintenance of CNS white matter

  5. Inhibition of pancreatic protein synthesis in this model of acute pancreatitis most likely results from inhibition of translation initiation from increased eIF2alpha (Montrer EIF2A Kits ELISA) phosphorylation, reduction of eIF2B (Montrer EIF2B4 Kits ELISA) activity, and inhibition of eIF4F (Montrer EIF4A2 Kits ELISA) complex formation.

  6. inactivation of glycogen synthase kinase 3beta (GSK3beta (Montrer GSK3b Kits ELISA)) by high glucose and high insulin (Montrer INS Kits ELISA) induces increase in synthesis of laminin beta1 via activation of eIF2Bepsilon.

Human Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5) interaction partners

  1. This study demonstrated that no evidence for a role of Ile587Val polymorphism of EIF2B5 gene in multiple sclerosis in Kashmir Valley if India.

  2. Patient exhibits an early-infantile onset and progressive disease course resembling Cree leukoencephalopathy, suggesting a severe functional disruption of eIF2Bepsilon caused by R195H as well as by I408T mutations.

  3. Missense mutations in EIF2B5 are associated with multiple sclerosis.

  4. Also a mutation c.1913G>A[p.Arg638 His] in exon 14 of the EIF2B5-Gens as single nucleotide polymorphism.

  5. crystal structure of the guanine nucleotide exchange factor for elf2

  6. Functional analysis of recently identified mutations in eukaryotic translation initiation factor (Montrer EIF2A Kits ELISA) 2Bepsilon (eIF2Bepsilon) identified in Chinese patients with vanishing white matter disease

  7. Cree leukoencephalopathy and CACH/VWM disease are allelic at the EIF2B5 locus.

  8. Mutation in EIF2B5 causes childhood ataxia with central nervous system hypomyelination/ vanishing white matter leukodystrophy.

  9. We demonstrated that mutations in the gene EIF2B5 cause "leukoencephalopathy with vanishing white matter." This gene encodes one of the five subunits of the translation factor eIF2B (Montrer EIF2B1 Kits ELISA).

  10. Biochemical analyses indicate that mutations analyzed in eIF2Balpha and -epsilon reduce the steady-state level of the affected subunit, while the most severe mutant tested, eIF2Bbeta(V341D), forms complexes with reduced stability and lower eIF2B (Montrer EIF2B1 Kits ELISA) activity.

EIF2B5 profil antigène

Antigen Summary

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

Gene names and symbols associated with EIF2B5

  • eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa (EIF2B5) anticorps
  • trimeric LpxA-like enzyme (AT2G34970) anticorps
  • trimeric LpxA-like enzyme (AT3G02270) anticorps
  • translation initiation factor eif-2b epsilon subunit (AOR_1_624154) anticorps
  • translation initiation factor eIF-2B epsilon subunit (CTRG_05484) anticorps
  • translation initiation factor eIF-2B epsilon subunit (PAAG_05066) anticorps
  • translation initiation factor eIF-2B epsilon subunit (CGB_A5380C) anticorps
  • translation initiation factor eif-2b epsilon subunit (TERG_01115) anticorps
  • eukaryotic translation initiation factor 2B, subunit 5 epsilon (Eif2b5) anticorps
  • AO090003000364 anticorps
  • C81315 anticorps
  • CACH anticorps
  • CLE anticorps
  • EIF-2B anticorps
  • EIF2B5 anticorps
  • EIF2Bepsilon anticorps
  • F14P3.8 anticorps
  • F14P3_8 anticorps
  • F19I3.20 anticorps
  • F19I3_20 anticorps
  • LVWM anticorps

Protein level used designations for EIF2B5

eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa , translation initiation factor eIF-2B subunit epsilon , translation initiation factor eIF-2B subunit epsilon-like , translation initiation factor eIF-2B epsilon subunit , translation initiation factor eif-2b epsilon subunit , eIF-2B GDP-GTP exchange factor subunit epsilon , initiation factor eIF-2Be , eIF-2Bepsilon

GENE ID SPECIES
424948 Gallus gallus
460881 Pan troglodytes
488103 Canis lupus familiaris
703673 Macaca mulatta
783760 Bos taurus
100389722 Callithrix jacchus
100446186 Pongo abelii
100580454 Nomascus leucogenys
818061 Arabidopsis thaliana
821200 Arabidopsis thaliana
5991536 Aspergillus oryzae RIB40
8300542 Candida tropicalis MYA-3404
9096172 Paracoccidioides sp. 'lutzii' Pb01
10187846 Cryptococcus gattii WM276
10373875 Trichophyton rubrum CBS 118892
224045 Mus musculus
192234 Rattus norvegicus
8893 Homo sapiens
100009393 Oryctolagus cuniculus
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