anti-Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) Anticorps

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. De plus, nous expédions EIF4G2 Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
EIF4G2 1982 P78344
EIF4G2 13690 Q62448
EIF4G2 361628  
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Top anti-EIF4G2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 116 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-EIF4G2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué WB 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Souris Inconjugué FACS, WB Flow Cytometry: DAP5 Antibody (39C534.1) [ABIN2659439] - Intracellular flow cytometric staining of 1 x 10^6 CHO (A) and HEK-293 (B) cells using antibody (dark blue). Isotype control shown in orange. An antibody concentration of 1 ug/1x10^6 cells was used. 0.1 mg Connectez-vous pour afficher 3 to 5 Days
363,75 €
Détails
Humain Souris Inconjugué WB EIF4G2 monoclonal antibody (M01), clone 3B5. Western Blot analysis of EIF4G2 expression in PC-12. 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-EIF4G2 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate Sample Type: 1. IAH30 cells (0.5x106 cells loaded)2. DF-1 cells (0.5x106 cells loaded)Primary Dilution: 1:1000 Secondary Antibody: Goat anti-rabbit IgG (whole molecule) peroxidase Secondary Dilution:1:10,000 Image Submitted By: Yongxiu YaoInstitute for Animal Health 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Souris Inconjugué IHC (p), WB 50 μg Connectez-vous pour afficher 8 to 10 Days
517,00 €
Détails
Humain Lapin Inconjugué IHC (p), WB IHC-P Image DAP5 antibody [C2C3], C-term detects DAP5 protein at cytosol on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. DAP5 antibody [C2C3], C-term , dilution: 1:500. WB Image Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 , 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Connectez-vous pour afficher 5 to 7 Days
357,24 €
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded human skeletal muscle , using DAP5, antibody(10 μg/ml). WB Image Sample(30 μg of whole cell lysate) A:A431, 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Connectez-vous pour afficher 5 to 7 Days
357,24 €
Détails
Humain Souris Inconjugué IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to EIF4G2 on formalin-fixed paraffin-embedded human heart. [antibody concentration 3 ug/ml] EIF4G2 monoclonal antibody (M01), clone 3B5 Western Blot analysis of EIF4G2 expression in Hela S3 NE . 100 μg Connectez-vous pour afficher 7 to 8 Days
369,60 €
Détails
Humain Lapin Inconjugué ELISA, IF, IHC, WB Western Blot (WB) analysis of specific cells using DAP-5 Polyclonal Antibody. 100 μL Connectez-vous pour afficher 13 Days
154,33 €
Détails

EIF4G2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-EIF4G2 Anticorps mieux référencés

  1. Human Monoclonal EIF4G2 Primary Antibody pour FACS, WB - ABIN265943 : Levy-Strumpf, Deiss, Berissi, Kimchi: DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell death. dans Molecular and cellular biology 1997 (PubMed)
    Show all 6 references for 265943

  2. Human Monoclonal EIF4G2 Primary Antibody pour WB - ABIN394226 : Frank, Virgili, Sonenberg, Nagar: Crystallization and preliminary X-ray diffraction analysis of the MIF4G domain of DAP5. dans Acta crystallographica. Section F, Structural biology and crystallization communications 2010 (PubMed)
    Show all 5 references for 394226

  3. Human Polyclonal EIF4G2 Primary Antibody pour WB - ABIN1944751 : Imataka, Olsen, Sonenberg: A new translational regulator with homology to eukaryotic translation initiation factor 4G. dans The EMBO journal 1997 (PubMed)
    Show all 3 references for 1944751

  4. Human Monoclonal EIF4G2 Primary Antibody pour IHC (p), ELISA - ABIN560721 : Katsogiannou, Andrieu, Baylot, Baudot, Dusetti, Gayet, Finetti, Garrido, Birnbaum, Bertucci, Brun, Rocchi: The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets. dans Molecular & cellular proteomics : MCP 2014 (PubMed)

  5. Cow (Bovine) Polyclonal EIF4G2 Primary Antibody pour IHC, WB - ABIN2778774 : Nousch, Reed, Bryson-Richardson, Currie, Preiss: The eIF4G-homolog p97 can activate translation independent of caspase cleavage. dans RNA (New York, N.Y.) 2007 (PubMed)

Plus d’anticorps contre EIF4G2 partenaires d’interaction

Zebrafish Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) interaction partners

Xenopus laevis Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) interaction partners

Human Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) interaction partners

  1. DAP5 knockdown from human ESCs (Montrer NR2E3 Anticorps) (hESCs) resulted in persistence of pluripotent gene expression, delayed induction of differentiation-associated genes in different cell lineages, and defective embryoid body formation

  2. Data show that microRNA miR (Montrer MLXIP Anticorps)-379 potentiated lung cancer (LCa (Montrer CLTA Anticorps)) chemosensitivity via modulation of cisplatin (CDDP)-induced apoptosis by directly targeting the eukaryotic translation initiation factor 4 gamma 2 (EIF4G2) 3' UTR (Montrer UTS2R Anticorps).

  3. These results indicate that miR (Montrer MLXIP Anticorps)-139 is capable of inhibiting chondrocyte proliferation and migration, thus being a possible therapeutic target for OA. The mechanism of miR (Montrer MLXIP Anticorps)-139 in chondrocytes may be related to its regulation on EIF4G2 and IGF1R (Montrer IGF1R Anticorps).

  4. The Coxsackievirus B3 protease 2A-mediated cleavage of DAP5 results in the production of two truncates that exert differential effects on protein translation of the IRES-containing genes, leading to enhanced host cell death.

  5. Knockdown of EIF4G2 recapitulated the effects of mir (Montrer MLXIP Anticorps)-139, whereas restoring EIF4G2 expression rescued the mir (Montrer MLXIP Anticorps)-139 phenotype. elevated miR (Montrer MLXIP Anticorps)-139-5p expression is associated with a favorable outcome in acute myeloid leukemia (Montrer BCL11A Anticorps).

  6. findings provide the first mechanistic insights into the function of DAP5 as a selective regulator of cap-independent translation

  7. Our results provide evidence that the tumor suppressor effect of miR (Montrer MLXIP Anticorps)-520c-3p is mediated through repression of translation while inducing senescence and that eIF4GII (Montrer EIF4G3 Anticorps) is a key effector of this anti-tumor activity.

  8. DAP5, a translation initiation factor shown to positively regulate the translation of various internal ribosome entry sites containing mRNAs, promotes internal ribosome entry site-driven translation of p53 (Montrer TP53 Anticorps) mRNA.

  9. DAP5/p97 and DAP5/p86 enhanced the translation of the anti-apoptotic protein Bcl-2 (Montrer BCL2 Anticorps) and inhibited cisplatin-induced apoptosis

  10. Multiple isoforms of eIF4GII (Montrer EIF4G3 Anticorps) arise from multiple promoters & alternative splicing events. A non-canonical CUG initiation codon extends the eIF4GII (Montrer EIF4G3 Anticorps) N-terminus. The eIF4GII (Montrer EIF4G3 Anticorps) N-terminus plays an alternative role in initiation factor assembly.

Mouse (Murine) Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) interaction partners

  1. analysis of the tandem MA-3 (Montrer PDCD6 Anticorps) region of Pdcd4 (Montrer PDCD4 Anticorps) protein and characterization of its interactions with eIF4A (Montrer EIF4A1 Anticorps) and eIF4G (Montrer EIF4G1 Anticorps)

EIF4G2 profil antigène

Profil protéine

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3\; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Gene names and symbols associated with EIF4G2

  • eukaryotic translation initiation factor 4, gamma 2b (eif4g2b) anticorps
  • eukaryotic translation initiation factor 4 gamma, 2 (EIF4G2) anticorps
  • eIF4G-related protein NAT1 (nat1) anticorps
  • eukaryotic translation initiation factor 4, gamma 2 (Eif4g2) anticorps
  • AA589388 anticorps
  • AAG1 anticorps
  • DAP-5 anticorps
  • DAP5 anticorps
  • E130105L11Rik anticorps
  • EIF4G2 anticorps
  • hm:zeh1307 anticorps
  • Nat1 anticorps
  • NAT1B anticorps
  • Natm1 anticorps
  • P97 anticorps
  • wu:fa14h01 anticorps
  • wu:fb44h01 anticorps
  • wu:fb59c06 anticorps
  • wu:fc21b05 anticorps

Protein level used designations for EIF4G2

eukaryotic translation initiation factor 4 gamma, 2 , fb44h01 , eukaryotic translation initiation factor 4 gamma 2 , Eukaryotic translation initiation factor 4 gamma 2 , DAP-5 , aging-associated protein 1 , death-associated protein 5 , eIF-4-gamma 2 , eIF-4G 2 , eIF4G 2 , eukaryotic translation initiation factor 4G-like 1 , eIF4G-related protein NAT1 , p97 , novel APOBEC-1 target 1 , translation repressor NAT1 , translation repressor Nat1

GENE ID SPECIES
334618 Danio rerio
466443 Pan troglodytes
705510 Macaca mulatta
100173304 Pongo abelii
496405 Xenopus laevis
1982 Homo sapiens
395905 Gallus gallus
476854 Canis lupus familiaris
286870 Bos taurus
100009236 Oryctolagus cuniculus
13690 Mus musculus
361628 Rattus norvegicus
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