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EXOSC8 encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. De plus, nous expédions Exosome Component 8 Protéines (9) et beaucoup plus de produits pour cette protéine.
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Knock-down of rbm7 (Montrer RBM7 Anticorps), exosc8 and exosc3 (Montrer EXOSC3 Anticorps) in zebrafish showed a common pattern of defects in motor neurons and cerebellum. Our data indicate that impaired RNA metabolism may underlie the clinical phenotype by fine tuning gene expression which is essential for correct neuronal differentiation
A protein subunit of human RNase P, Rpp14 (Montrer RPP14 Anticorps), and its interacting partner, OIP2, have 3'-->5' exoribonuclease activity.
Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase (Montrer PNPT1 Anticorps)-like ring.
This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.
exosome complex exonuclease RRP43
, Opa-interacting protein 2 (3' exoribonuclease family)
, exosome component 8
, exosome complex component RRP43
, CBP-interacting protein 3
, Opa interacting protein 2
, opa-interacting protein 2
, ribosomal RNA-processing protein 43