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anti-F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) Anticorps

FBXL3 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. De plus, nous expédions F-Box and Leucine-Rich Repeat Protein 3 Kits (16) et F-Box and Leucine-Rich Repeat Protein 3 Protéines (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
FBXL3 26224 Q9UKT7
FBXL3 50789 Q8C4V4
FBXL3 306129  
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Top anti-F-Box and Leucine-Rich Repeat Protein 3 Anticorps sur anticorps-enligne.fr

Showing 10 out of 65 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Souris Lapin Inconjugué WB Western blot analysis of extracts from NIH/3T3 cells using FBXL3. 0.1 mL Connectez-vous pour afficher 8 to 10 Days
352,00 €
Détails
Poulet Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Chèvre Inconjugué ELISA, WB ABIN185700 (1µg/ml) staining of Human Adipose lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 3 to 4 Days
349,82 €
Détails
Chien Chèvre Inconjugué WB 0.1 mg Connectez-vous pour afficher 8 to 10 Days
357,50 €
Détails
Humain Souris Inconjugué WB FBXL3 monoclonal antibody (M03), clone 1A3. Western Blot analysis of FBXL3 expression in HeLa. 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails
Humain Souris Inconjugué ELISA, WB Detection limit for recombinant GST tagged FBXL3 is approximately 1 ng/mL as a capture antibody. 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails
Humain Lapin Inconjugué ICC, IF, WB WB Image Sample (30 ug of whole cell lysate) A: Molt-4 , 10% SDS PAGE antibody diluted at 1:1000 WB Image FBXL3 antibody detects FBXL3 protein by Western blot analysis. A. 30 µg C2C12 whole cell lysate/extract 10 % SDS-PAGE FBXL3 antibody , dilution: 1:500 100 μL Connectez-vous pour afficher 5 to 7 Days
357,24 €
Détails
Humain Chèvre Inconjugué IHC (p), ELISA, WB Human Thyroid (formalin-fixed, paraffin-embedded) stained with FBXL3 antibody ABIN351492 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 11 to 14 Days
501,70 €
Détails
Chien Chèvre Inconjugué EIA, IHC (p), WB 50 μg Connectez-vous pour afficher 8 to 10 Days
517,00 €
Détails
Humain Souris Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 11 to 14 Days
635,55 €
Détails

FBXL3 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-F-Box and Leucine-Rich Repeat Protein 3 Anticorps mieux référencés

  1. Human Monoclonal FBXL3 Primary Antibody pour ELISA, WB - ABIN393683 : Busino, Bassermann, Maiolica, Lee, Nolan, Godinho, Draetta, Pagano: SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins. dans Science (New York, N.Y.) 2007 (PubMed)
    Show all 5 references for ABIN393683

  2. Human Monoclonal FBXL3 Primary Antibody pour WB - ABIN393439 : Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ... dans Genome research 2006 (PubMed)
    Show all 5 references for ABIN393439

  3. Mouse (Murine) Polyclonal FBXL3 Primary Antibody pour WB - ABIN783328 : Winston, Koepp, Zhu, Elledge, Harper: A family of mammalian F-box proteins. dans Current biology : CB 1999 (PubMed)
    Show all 3 references for ABIN783328

  4. Human Polyclonal FBXL3 Primary Antibody pour ELISA, WB - ABIN185700 : Albig, Neil, Schiemann: Fibulins 3 and 5 antagonize tumor angiogenesis in vivo. dans Cancer research 2006 (PubMed)

Plus d’anticorps contre F-Box and Leucine-Rich Repeat Protein 3 partenaires d’interaction

Human F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) interaction partners

  1. Data show that CRISPR/Cas9 genome editing generated F-box and leucine-rich repeat protein 3 (Fbxl3) knockout in circadian clock model U2OS cells.

  2. Substrate binding promotes formation of the Skp1 (Montrer SKP1 Anticorps)-Cul1 (Montrer CUL1 Anticorps)-Fbxl3 (SCF (Montrer KITLG Anticorps)(Fbxl3)) protein complex.

  3. Mutation in the Fbxl3 protein reveals distinct roles for CRY1 (Montrer CRY1 Anticorps) and CRY2 (Montrer CRY2 Anticorps) in the circadian molecular clockwork.

  4. crystal structures of mammalian CRY2 (Montrer CRY2 Anticorps) in its apo (Montrer C9orf3 Anticorps), FAD (Montrer BRCA2 Anticorps)-bound and FBXL3-SKP1 (Montrer SKP1 Anticorps)-complexed forms

  5. study demonstrates that the SCF (Montrer KITLG Anticorps)(Fbxl3)ubiquitin ligase controls the oscillations of the circadian clock by mediating the degradation of Cry1 (Montrer CRY1 Anticorps) and Cry2 (Montrer CRY2 Anticorps) proteins

Mouse (Murine) F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) interaction partners

  1. Substrate binding promotes formation of the Skp1 (Montrer SKP1 Anticorps)-Cul1 (Montrer CUL1 Anticorps)-Fbxl3 (SCF (Montrer KITLG Anticorps)(Fbxl3)) protein complex.

  2. By analyzing the Fbxl3 and Cryptochrome 1 (Montrer CRY1 Anticorps) double-mutant mice, we found that FBXL3 also regulates the amplitudes of E-box-driven gene expression.

  3. crystal structures of mammalian CRY2 (Montrer CRY2 Anticorps) in its apo (Montrer C9orf3 Anticorps), FAD (Montrer FANCD2 Anticorps)-bound and FBXL3-SKP1 (Montrer SKP1 Anticorps)-complexed forms

  4. FBXL21 (Montrer FBXL21 Anticorps) plays a dual role: protecting CRY 1 (Montrer CRY1 Anticorps)/2 proteins (CRY (Montrer CRY2 Anticorps)) from FBXL3 degradation in the nucleus and promoting CRY (Montrer CRY2 Anticorps) degradation within the cytoplasm.

  5. results are consistent with previous studies of mutants with extended circadian periods and suggest that disruption of FBXL3 is associated with mania-like behaviours in both mice and humans

  6. In Ovtm mice, expression of the PERIOD proteins is reduced; however, the CRY (Montrer CRY2 Anticorps) proteins are unchanged; the loss of FBXL3 function leads to a stabilization of the CRY (Montrer CRY2 Anticorps) proteins, which leads to a global transcriptional repression of the Per and Cry (Montrer CRY2 Anticorps) genes.

  7. study demonstrates that the SCF (Montrer KITLG Anticorps)(Fbxl3)ubiquitin ligase (Montrer RNF123 Anticorps) controls the oscillations of the circadian clock by mediating the degradation of Cry1 (Montrer CRY1 Anticorps) and Cry2 (Montrer CRY2 Anticorps) proteins

  8. studies reveal a central role for Fbxl3 in mammalian circadian timekeeping

F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) profil antigène

Profil protéine

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.

Gene names and symbols associated with FBXL3

  • F-box and leucine-rich repeat protein 3 (fbxl3) anticorps
  • F-box and leucine-rich repeat protein 3 (FBXL3) anticorps
  • similar to F-box and leucine-rich repeat protein 8 (FBXL3) anticorps
  • F-box and leucine-rich repeat protein 3 (Fbxl3) anticorps
  • F-box/LRR-repeat protein 3 (AT5G01720) anticorps
  • AU041772 anticorps
  • AW212966 anticorps
  • F7A7.240 anticorps
  • F7A7_240 anticorps
  • FBK anticorps
  • FBL3 anticorps
  • Fbl3a anticorps
  • FBXL3 anticorps
  • Fbxl3a anticorps
  • Ovtm anticorps
  • Play68 anticorps

Protein level used designations for FBXL3

F-box and leucine-rich repeat protein 3 , F-box/LRR-repeat protein 3 , F-box/LRR-repeat protein 3-like , f-box/LRR-repeat protein 3-like , similar to F-box and leucine-rich repeat protein 8 , F-box and leucine-rich repeat protein 3A , F-box protein Fbl3a , F-box/LRR-repeat protein 3A , F-box and leucine-rich repeat protein 3a , protein after-hours , protein overtime

GENE ID SPECIES
548882 Xenopus (Silurana) tropicalis
699028 Macaca mulatta
100010986 Monodelphis domestica
100052811 Equus caballus
100169937 Ovis aries
100413726 Callithrix jacchus
100450887 Pongo abelii
100556180 Anolis carolinensis
698286 Macaca mulatta
100081796 Ornithorhynchus anatinus
100469040 Ailuropoda melanoleuca
100580993 Nomascus leucogenys
26224 Homo sapiens
485499 Canis lupus familiaris
100152980 Sus scrofa
50789 Mus musculus
306129 Rattus norvegicus
564855 Danio rerio
446817 Xenopus laevis
428048 Gallus gallus
540712 Bos taurus
831688 Arabidopsis thaliana
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