anti-Family with Sequence Similarity 3, Member C (FAM3C) Anticorps

FAM3C is a member of the family with sequence similarity 3 (FAM3) family and encodes a secreted protein with a GG domain. De plus, nous expédions FAM3C Protéines (17) et FAM3C Kits (2) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
FAM3C 10447 Q92520
FAM3C 27999 Q91VU0
FAM3C 312159 Q810F4
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Top anti-FAM3C Anticorps sur anticorps-enligne.fr

Showing 10 out of 53 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-FAM3C Antibody Titration: 0.2-1 ug/mlPositive Control: 721_B cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
653,02 €
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Paraformaldehyde-fixed, paraffin embedded rat brain, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with FAM3C Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining. 100 μL Connectez-vous pour afficher 9 to 12 Days
304,36 €
Détails
Poulet Lapin Inconjugué IHC (p), IHC, WB Immunohistochemistry-Paraffin: FAM3C Antibody [NBP1-39744] - Staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 0.05 mg Connectez-vous pour afficher 3 to 5 Days
426,25 €
Détails
Humain Lapin Inconjugué IHC (p), WB 50 μg Connectez-vous pour afficher 8 to 10 Days
456,00 €
Détails
Poulet Lapin Inconjugué IHC (p), WB Human Skin (formalin-fixed, paraffin-embedded) stained with FAM3C antibody ABIN293839 at 5-10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 11 to 14 Days
501,70 €
Détails
Poulet Lapin Inconjugué IHC, WB 0.05 mg Connectez-vous pour afficher 6 to 8 Days
538,22 €
Détails
Humain Lapin Alexa Fluor 350 IF (p)   100 μL Connectez-vous pour afficher 18 to 22 Days
414,64 €
Détails
Humain Lapin Alexa Fluor 488 IF (p)   100 μL Connectez-vous pour afficher 18 to 22 Days
414,64 €
Détails
Humain Lapin Alexa Fluor 555 IF (p)   100 μL Connectez-vous pour afficher 18 to 22 Days
414,64 €
Détails

FAM3C Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-FAM3C Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal FAM3C Primary Antibody pour WB - ABIN2782061 : Dublineau, Grison, Grandcolas, Baudelin, Tessier, Suhard, Frelon, Cossonnet, Claraz, Ritt, Paquet, Voisin, Gourmelon: Absorption, accumulation and biological effects of depleted uranium in Peyer's patches of rats. dans Toxicology 2006 (PubMed)
    Show all 2 references for 2782061

Plus d’anticorps contre FAM3C partenaires d’interaction

Human Family with Sequence Similarity 3, Member C (FAM3C) interaction partners

  1. Data suggest that ILEI does not form interleukin-like four helix-bundle structures; ILEI exists as monomers and as covalent dimers; ILEI dimer exhibits a trans-linked domain swap converting an intramolecular disulfide to an intermolecular disulfide; dimeric ILEI appears to be involved in neoplastic invasiveness.

  2. Results demonstrate that phenotype switching regulates ILEI expression, and that ILEI regulates partial phenotype switching in MITF (Montrer MITF Anticorps)-low melanoma cell lines.

  3. Ectopic overexpression of UBE4A (Montrer UBE4A Anticorps), but not UBE3C (Montrer UBE3C Anticorps), in cells was downregulated in vitro migration and invasion in these cells. Cumulatively, our data reveals a novel post-translational regulatory mechanism of regulating ILEI1 expression, a protein required for metastatic progression in prostate cancer cells

  4. Study used immunohistochemical staining and biochemical fractionation to examine the regional distribution and subcellular localization of ILEI in mouse brains and in autopsy brains of patients with Alzheimer's disease; results suggest that a decline of ILEI expression may cause accumulation of Abeta (Montrer APP Anticorps) in the brain and the eventual development of Alzheimer's disease.

  5. FAM3C expression was dramatically increased in esophageal squamous cell carcinoma and might serve as a valuable prognostic indicator for esophageal squamous cell carcinoma patients after surgery

  6. Altered subcellular ILEI localization strongly correlates with high tumor cell-associated uPAR (Montrer PLAUR Anticorps) protein expression.

  7. Our findings indicate that cytoplasmic ILEI expression is a potential marker of EMT (Montrer ITK Anticorps) and tumour progression in colorectal cancer. ILEI is an independent predictive factor associated with poor prognosis in colorectal cancer.

  8. ILEI could induce, as well as maintain, CD24 (Montrer CD24 Anticorps)(low)CD44 (Montrer CD44 Anticorps)(high) subpopulation in A549 cells treated with TGF-beta (Montrer TGFB1 Anticorps), which might explain its capability to induce metastatic progression.

  9. At the FAM3C gene locus where rs7776725 was located, we identified several other SNPs (rs4727922, rs1803389, rs718766 and rs7793554) that were also associated with BMD (Montrer BEST1 Anticorps).

  10. ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors.

Mouse (Murine) Family with Sequence Similarity 3, Member C (FAM3C) interaction partners

  1. Data suggest that Ilei does not form interleukin-like four helix-bundle structures; Ilei exists as monomers and as covalent dimers; Ilei dimer exhibits a trans-linked domain swap converting an intramolecular disulfide to an intermolecular disulfide; dimeric Ilei appears to be involved in neoplastic invasiveness.

  2. overexpression of Fam3c caused reduction of Runx2 (Montrer RUNX2 Anticorps) expression at both mRNA and protein levels. Fam3c was localized in the cytoplasm and it was not secreted outside the cell during osteoblast differentiation and therefore, may function intracellularly. Furthermore, Fam3c and TGF-beta1 (Montrer TGFB1 Anticorps) were found to regulate each other reciprocally

  3. In obese diabetic mice, FAM3C expression was reduced in the liver, and hepatic FAM3C restoration improved insulin (Montrer INS Anticorps) resistance, hyperglycemia, and fatty liver. FAM3C overexpression increased the expression of heat shock factor 1 (HSF1), calmodulin (CaM (Montrer Calm2 Anticorps)), and phosphorylated Akt (Montrer AKT1 Anticorps) and reduced that of gluconeogenic and lipogenic genes in diabetic mouse livers with the suppression of gluconeogenesis and lipid deposition.

  4. Study used immunohistochemical staining and biochemical fractionation to examine the regional distribution and subcellular localization of ILEI in mouse brains and in autopsy brains of patients with Alzheimer's disease; results suggest that a decline of ILEI expression may cause accumulation of Abeta (Montrer APP Anticorps) in the brain and the eventual development of Alzheimer's disease.

  5. TGF-beta (Montrer TGFB1 Anticorps) modulates the expression of Dab2 (Montrer DAB2 Anticorps) and ILEI mRNA required for epithelial-mesenchymal transdifferentiation by inducing phosphorylation of hnRNP E1 (Montrer PCBP1 Anticorps), resulting in its release from a structural, 33-nucleotide BAT (Montrer BAAT Anticorps) element in the 3'UTR (Montrer UTS2R Anticorps) of Dab2 (Montrer DAB2 Anticorps) and ILEI.

  6. FAM3C orthologous protein, may be involved in cell differentiation and proliferation during inner ear embryogenesis

  7. ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors.

  8. ILEI requires cooperation with oncogenic Ras to govern hepatocellular EMT (Montrer ITK Anticorps) through mechanisms involving PDGF-R/beta (Montrer PDGFRB Anticorps)-catenin (Montrer CTNNB1 Anticorps) and PDGF (Montrer PDGFA Anticorps)-R/Stat3 (Montrer STAT3 Anticorps) signaling.

FAM3C profil antigène

Profil protéine

This gene is a member of the family with sequence similarity 3 (FAM3) family and encodes a secreted protein with a GG domain. A change in expression of this protein has been noted in pancreatic cancer-derived cells.

Gene names and symbols associated with FAM3C

  • family with sequence similarity 3, member C (fam3c) anticorps
  • family with sequence similarity 3, member C (LOC100221204) anticorps
  • family with sequence similarity 3, member C (FAM3C) anticorps
  • family with sequence similarity 3, member C (Fam3c) anticorps
  • D6Wsu176e anticorps
  • Ilei anticorps
  • wu:fb99h11 anticorps
  • wu:fi35h03 anticorps
  • zgc:55444 anticorps
  • zgc:77090 anticorps

Protein level used designations for FAM3C

hypothetical protein LOC549860 , Protein FAM3C , family with sequence similarity 3, member C , protein FAM3C , interleukin-like EMT inducer , predicted osteoblast protein , FAM3C-like protein

GENE ID SPECIES
549860 Xenopus (Silurana) tropicalis
100221204 Taeniopygia guttata
417758 Gallus gallus
463680 Pan troglodytes
10447 Homo sapiens
612336 Canis lupus familiaris
615690 Bos taurus
27999 Mus musculus
312159 Rattus norvegicus
334205 Danio rerio
443905 Xenopus laevis
Fournisseurs de qualité sélectionnés pour anti-FAM3C (FAM3C) Anticorps
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