anti-Fibulin 5 (FBLN5) Anticorps

The protein encoded by FBLN5 is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. De plus, nous expédions Fibulin 5 Kits (34) et Fibulin 5 Protéines (15) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
FBLN5 10516 Q9UBX5
FBLN5 23876 Q9WVH9
FBLN5 29158 Q9WVH8
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Top anti-Fibulin 5 Anticorps sur anticorps-enligne.fr

Showing 10 out of 135 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Chèvre Inconjugué ELISA, WB ABIN185699 (0.1µg/ml) staining of Human Ovary lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 3 to 4 Days
349,82 €
Détails
Humain Souris Inconjugué ELISA, WB Figure 1: Western blot analysis using fibulin5 mouse mAb against truncated fibulin5 recombinant protein (1) and Hela cell lysate (2) . 100 μL Connectez-vous pour afficher 6 to 8 Days
317,98 €
Détails
Humain Chèvre Inconjugué ELISA, WB ABIN251669 (0.1?g/ml) staining of Human Ovary lysate (35?g protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Connectez-vous pour afficher 3 to 5 Days
388,75 €
Détails
Humain Souris Inconjugué IHC, ELISA, WB Figure 1: Immunohistochemical analysis of paraffin-embedded human colon cancer (left) and breast cancer (right) showing cytoplasmic localization with DAB staining using FBLN5 mouse mAb. Figure 2: Western blot analysis using FBLN5 mouse mAb against truncated FBLN5-His recombinant protein. 100 μL Connectez-vous pour afficher 6 to 8 Days
507,79 €
Détails
Humain Souris Inconjugué IHC, ELISA, WB Figure 1: Immunohistochemical analysis of paraffin-embedded human stomach carcinoma (left) and breast carcinoma (right), showing cytoplasmic localization using fibulin5 mouse mAb with DAB staining. Figure 2: Western blot analysis using Fibulin5 mouse mAb against truncated fibulin5 recombinant protein (1) and Hela cell lysate (2) . 100 μL Connectez-vous pour afficher 6 to 8 Days
507,79 €
Détails
Humain Souris Inconjugué EIA, IHC (p), WB 0.1 mL Connectez-vous pour afficher 8 to 10 Days
330,00 €
Détails
Chien Chèvre Inconjugué WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
357,50 €
Détails
Humain Lapin Inconjugué ELISA, WB Western Blot (WB) analysis of specific cells using Fibulin-5 Polyclonal Antibody. 100 μL Connectez-vous pour afficher 13 Days
154,33 €
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using FBLN5 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails
Humain Chèvre Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 11 to 14 Days
705,40 €
Détails

FBLN5 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Fibulin 5 Anticorps mieux référencés

  1. Human Monoclonal Fibulin 5 Primary Antibody pour IHC, ELISA - ABIN969131 : Markova, Zou, Ringpfeil, Sasaki, Kostka, Timpl, Uitto, Chu: Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene. dans American journal of human genetics 2003 (PubMed)
    Show all 4 references for 969131

  2. Human Monoclonal Fibulin 5 Primary Antibody pour IHC, ELISA - ABIN969144 : Wen, Hochholdinger, Sauer, Bruce, Schnable: The roothairless1 gene of maize encodes a homolog of sec3, which is involved in polar exocytosis. dans Plant physiology 2005 (PubMed)
    Show all 4 references for 969144

  3. Human Monoclonal Fibulin 5 Primary Antibody pour ELISA, WB - ABIN969145 : Kadoya, Sasaki, Kostka, Timpl, Matsuzaki, Kumagai, Sakai, Nishiyama, Amano: Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis. dans The British journal of dermatology 2005 (PubMed)
    Show all 4 references for 969145

  4. Human Monoclonal Fibulin 5 Primary Antibody pour EIA, IHC (p) - ABIN1107240 : Lee, Roy, Mogford, Schiemann, Mustoe: Fibulin-5 promotes wound healing in vivo. dans Journal of the American College of Surgeons 2004 (PubMed)
    Show all 3 references for 1107240

  5. Human Polyclonal Fibulin 5 Primary Antibody pour ELISA, WB - ABIN185699 : Albig, Neil, Schiemann: Fibulins 3 and 5 antagonize tumor angiogenesis in vivo. dans Cancer research 2006 (PubMed)

Plus d’anticorps contre Fibulin 5 partenaires d’interaction

Human Fibulin 5 (FBLN5) interaction partners

  1. Data show that fibulin-5 strongly binds to the endothelial cell surface reducing endothelial cell viability and interfering with the signaling pathways of the Ang-1 (Montrer ANGPT1 Anticorps)/TIE-2 (Montrer TEK Anticorps) receptor axis.

  2. FBLN5 downregulation in human abdominal aortic aneurysm could contribute to extracellular matrix remodeling induced by the inflammatory component of the disease.

  3. Identify a SOX9 (Montrer SOX9 Anticorps)/HDAC (Montrer HDAC3 Anticorps)-dependent mechanism involved in the down-regulation of FBLN5 by inflammation in abdominal aortic aneurysms.

  4. We also found that Fibulin-5 reduces the level of expression of Ki-67 (Montrer MKI67 Anticorps), a nuclear protein (Montrer RDBP Anticorps) associated with cell proliferation. Moreover, reduction in Fibulin-5 expression corresponds to an increase of Ki-67 (Montrer MKI67 Anticorps) detection in breast tissue samples

  5. study demonstrates the pivotal role of the extracellular protein, fibulin-5, on the adhesion and proliferation of human keloid-derived cells, through binding to integrin beta-1 (Montrer ITGB1 Anticorps)

  6. Lower FBLN-5 expression is an important indicator of poor survival in hepatocellular carcinoma. FBLN-5 inhibits HCC (Montrer FAM126A Anticorps) adhesion/motility via integrin-dependent mechanism.

  7. FBLN5 mRNA expression is upregulated in response to cAMP-mediated decidualization of primary human endometrial stromal cells, although FBLN5 itself does not enhance decidualization

  8. Fibulin-5 is significantly down-regulated in ovarian carcinoma and acts as a tumour suppressor by inhibiting the migration and invasion of ovarian cancer cells.

  9. Data indicate that Fbln5 promotes PDAC progression by functioning as a molecular rheostat that modulates cell-ECM (Montrer MMRN1 Anticorps) interactions to reduce ROS (Montrer ROS1 Anticorps) production, and thus tip the balance in favor of tumor cell survival and treatment-refractory disease.

  10. Data suggest that fibulin-5 functions as a metastasis suppressor in lung cancer by modulating tumor microenvironment to suppress Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) signaling.

Mouse (Murine) Fibulin 5 (FBLN5) interaction partners

  1. therapy-induced hypoxia elevated Fbln5 expression, whereas pharmacologic inhibition of TGF-beta (Montrer TGFB1 Anticorps) signaling reduced Fbln5 expression. These findings offer insight into the signaling axis that induces Fbln5 expression in PDA and a potential strategy to block its production

  2. Identify a SOX9 (Montrer SOX9 Anticorps)/HDAC (Montrer HDAC3 Anticorps)-dependent mechanism involved in the down-regulation of FBLN5 by inflammation in abdominal aortic aneurysms.

  3. Data indicate that Fbln5 promotes PDAC progression by functioning as a molecular rheostat that modulates cell-ECM (Montrer MMRN1 Anticorps) interactions to reduce ROS (Montrer ROS1 Anticorps) production, and thus tip the balance in favor of tumor cell survival and treatment-refractory disease.

  4. While premaxillo-maxillary suture mesenchymal cells in fibulin-5-null mice were capable of differentiating into osteoblasts, suture cells in mutant mice were less proliferative.

  5. Fibulin-5 plays critical roles in proliferation, migration and invasion of certain tumors, and the effect of fibulin-5 on tumorigenesis appears to be largely context-dependent. (Review)

  6. These results are consistent with a role for TGFbeta2 in lung septation and for Ltbp4 (Montrer LTBP4 Anticorps) in regulating fibulin-5 dependent elastic fiber assembly.

  7. Without LTBP-4 (Montrer LTBP4 Anticorps), fibulin-5 and tropoelastin (Montrer ELN Anticorps) deposition was discontinuous and punctate in vitro and in vivo

  8. This study used the maturation of fibulin-5 knockout (KO) and wild-type mice to study the effects of fragmented elastic fibers on the growth and remodeling of carotid arteries.

  9. suggest that uPA (Montrer PLAU Anticorps) promotes cell migration by binding to fibulin-5, initiating its cleavage by plasmin (Montrer PLG Anticorps), which leads to its dissociation from beta1-integrin and thereby unblocks the capacity of integrin to facilitate cell motility

  10. MMP9 (Montrer MMP9 Anticorps) and fibulin-5 have roles in progression of pelvic organ prolapse in mice and humans

Cow (Bovine) Fibulin 5 (FBLN5) interaction partners

  1. These results suggest a novel regulatory mechanism of elastic fiber assembly in which LTBP-2 (Montrer LTBP2 Anticorps) regulates targeting of DANCE on suitable microfibrils to form elastic fibers.

Fibulin 5 (FBLN5) profil antigène

Profil protéine

The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).

Gene names and symbols associated with anti-Fibulin 5 (FBLN5) Anticorps

  • fibulin 5 (fbln5) anticorps
  • fibulin 5 (FBLN5) anticorps
  • fibulin 5 (LOC100222931) anticorps
  • fibulin 5 (Fbln5) anticorps
  • Fibulin 5 (LOC100155248) anticorps
  • A55 anticorps
  • ADCL2 anticorps
  • ARCL1A anticorps
  • ARMD3 anticorps
  • DANCE anticorps
  • DKFZp469K0327 anticorps
  • EVEC anticorps
  • FBLN5 anticorps
  • FIBL-5 anticorps
  • Fibulin-5 anticorps
  • MGC108414 anticorps
  • UP50 anticorps
  • zgc:103575 anticorps

Protein level used designations for anti-Fibulin 5 (FBLN5) Anticorps

fibulin-5 , fibulin 5 , fibulin-5-like , developmental arteries and neural crest EGF-like protein , urine p50 protein , FIBL-5 , EVEC , dance , embryonic vascular EGF repeat-containing protein

GENE ID SPECIES
449806 Danio rerio
453112 Pan troglodytes
595007 Xenopus (Silurana) tropicalis
697372 Macaca mulatta
100172278 Pongo abelii
100222931 Taeniopygia guttata
100392828 Callithrix jacchus
100480209 Ailuropoda melanoleuca
100588580 Nomascus leucogenys
10516 Homo sapiens
480227 Canis lupus familiaris
23876 Mus musculus
29158 Rattus norvegicus
535185 Bos taurus
100347343 Oryctolagus cuniculus
100715192 Cavia porcellus
100155248 Sus scrofa
423413 Gallus gallus
101112927 Ovis aries
100063331 Equus caballus
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