Forkhead Box I1 Protéines (FOXI1)

FOXI1 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. De plus, nous expédions FOXI1 Anticorps (103) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
FOXI1 2299 Q12951
FOXI1 14233 Q922I5
Rat FOXI1 FOXI1 287185  
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Showing 7 out of 8 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$5,442.50
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$5,442.50
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$405.71
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher 10 to 12 Days
$785.40
Détails
Escherichia coli (E. coli) Humain His tag Validation with Western Blot 50 μg Connectez-vous pour afficher 10 to 12 Days
$229.85
Détails
Levure Xenopus tropicalis His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,992.00
Détails
Levure Xenopus laevis His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$3,023.17
Détails

FOXI1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , , ,
, ,
Mouse (Murine)

Plus protéines pour Forkhead Box I1 (FOXI1) partenaires d'interaction

Zebrafish Forkhead Box I1 (FOXI1) interaction partners

  1. Data indicate that foxi1 is expressed in branchial arch ectoderm and endoderm, and morpholino knock-down of foxi1 causes apoptosis of neural crest in the branchial arches, which is rescued by fgf3 (Montrer FGF3 Protéines).

  2. Foxi1 and Dlx3b/4b regulate the neuronal and sensory lineages of the inner ear.

  3. pax8 (Montrer PAX8 Protéines) works with related genes pax2a/pax2b to downregulate otic expression of foxi1, a necessary step for further otic development

  4. Data show that the hearsay mutation disrupts foxi1, a forkhead domain-containing gene, expressed in otic precursor cells before placodes become visible, and which appears to be the earliest marker known for the otic anlage.[foxi1]

  5. Foxi1 is necessary for pax8 (Montrer PAX8 Protéines) expression in the otic placode allowing fgf3 (Montrer FGF3 Protéines)/8 activation and also for pax8 (Montrer PAX8 Protéines) expression in the pharyngeal pouchs. Foxi1 is also necessary to maintain fgf3 (Montrer FGF3 Protéines) expression in the pharyngeal pouchs.

  6. FoxI1 is capable of remodeling chromatin higher-order structure and can stably create site-specific changes in chromatin to either stably create or remove DNase I (Montrer DNASE1 Protéines) hypersensitive sites.

  7. Foxi1 provide competence for cells to respond to Fgf and form an otic placode

Human Forkhead Box I1 (FOXI1) interaction partners

  1. study reveals that Foxi1/miR (Montrer MLXIP Protéines)-491-5p/Wnt3a (Montrer WNT3A Protéines)/beta-catenin (Montrer CTNNB1 Protéines) signaling is critical in the progression of GC. Targeting the pathway described in this study may open up new prospects to restrict the progression of gastric cancer

  2. We found no evidence for a significant association between mutations of KCNJ10 (Montrer KCNJ10 Protéines) and FOXI1 with SLC26A4 (Montrer SLC26A4 Protéines) in Pendred syndrome/enlarged vestibular aqueducts.

  3. No FOXI1 mutations were present in bilateral deafness patients with inner ear malformation.

  4. SLC26A4 (Montrer SLC26A4 Protéines), FOXI1 and KCNJ10 (Montrer KCNJ10 Protéines) are not major determinants in unilateral deafness and enlarged vestibular aqueduct

  5. C/EBP alpha (Montrer CEBPA Protéines) and HNF-3 gamma (Montrer FOXA3 Protéines) cooperatively regulate CYP3A4 (Montrer CYP3A4 Protéines) expression in hepatic cells by a mechanism that probably involves chromatin remodeling.

  6. Data suggestthat Foxi1 is necessary for expression of at least four subunits in three different epithelia and most likely is a major determinant for proper assembly of a functional vacuolar H(+)-ATPase (Montrer ATP6V1B2 Protéines) complex at these locations.

Mouse (Murine) Forkhead Box I1 (FOXI1) interaction partners

  1. mutations in FOXI1 could prove to cause a Pendred syndrome-like human deafness

  2. examined the expression patterns of the Foxi class genes from embryonic day 6.5 to 10.5; Foxi1 expression is first detected in the endolymphatic duct in the otic vesicle at E10.5

  3. The AE4 promoter is identified as a direct target of Foxi1.

  4. Spermatozoa from Foxi1 null males fail to reach the female genital tract in sufficient number to allow fertilization.

  5. Data suggestthat Foxi1 is necessary for expression of at least four subunits in three different epithelia and most likely is a major determinant for proper assembly of a functional vacuolar H(+)-ATPase (Montrer ATP6V1B2 Protéines) complex at these locations.

  6. Foxa1 (Montrer FOXA1 Protéines) and Foxi1 are required for later stage sweat gland development.

Xenopus laevis Forkhead Box I1 (FOXI1) interaction partners

  1. Foxi2 thus acts as a link between the oocyte and the early pathway to ectoderm

  2. Xema is both necessary and sufficient for the inhibition of ectopic mesendoderm in the cells of the presumptive ectoderm

Profil protéine FOXI1

Profil protéine

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined\; however, it is possible that this gene plays an important role in the development of the cochlea and vestibulum, as well as embryogenesis. Mutations in this gene may be associated with the common cavity phenotype. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Forkhead Box I1 Protéines (FOXI1)

  • forkhead box I3b (foxi3b)
  • forkhead box I1 (foxi1)
  • forkhead box I1 (FOXI1)
  • forkhead box protein I1 (CC1G_14832)
  • forkhead box I1 (Foxi1)
  • forkhead box I1 L homeolog (foxi1.L)
  • forkhead box i1 (foxi1)
  • 5830401E05Rik Protéine
  • cb724 Protéine
  • ema Protéine
  • Fkh10 Protéine
  • FKHL10 Protéine
  • foo Protéine
  • FOXI1 Protéine
  • foxi1a Protéine
  • foxi1e Protéine
  • FREAC-6 Protéine
  • FREAC6 Protéine
  • HFH-3 Protéine
  • Hfh3 Protéine
  • xema Protéine
  • xfoxi1 Protéine
  • Xfoxi1a Protéine

Protein level used designations for Forkhead Box I1 Protéines (FOXI1)

forkhead box protein I1 , Xenopus ectodermally-expressed mesendoderm antagonist , ectodermally-expressed mesendoderm antagon , ectodermally-expressed mesendoderm antagonist , forkhead box protein I1-ema , foxI1-ema , foxI3 , forkhead box I1 , forkhead box protein I1-like , HNF-3/fork-head homolog 3 , HNF-3/fork-head homolog-3 , forkhead-like 10 , forkhead-related activator 6 , forkhead-related protein FKHL10 , forkhead-related transcription factor 6 , hepatocyte nuclear factor 3 forkhead homolog 3 , HNF-3/forkhead homolog 3 , forkhead homolog 10 , hearsay , hsy , no soul , nos , quadro , quo(l)

GENE ID SPECIES
387258 Danio rerio
394546 Xenopus (Silurana) tropicalis
471732 Pan troglodytes
700122 Macaca mulatta
9379322 Coprinopsis cinerea okayama7130
100397090 Callithrix jacchus
100455511 Pongo abelii
2299 Homo sapiens
539442 Bos taurus
14233 Mus musculus
287185 Rattus norvegicus
380059 Xenopus laevis
427613 Gallus gallus
353313 Danio rerio
489127 Canis lupus familiaris
100511481 Sus scrofa
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