anti-Four and A Half LIM Domains 1 (FHL1) Anticorps

FHL1 encodes a member of the four-and-a-half-LIM-only protein family. De plus, nous expédions Four and A Half LIM Domains 1 Kits (10) et Four and A Half LIM Domains 1 Protéines (10) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
FHL1 2273 Q13642
FHL1 14199 P97447
FHL1 25177 Q9WUH4
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Top anti-Four and A Half LIM Domains 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 107 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IC, IF, WB 200 μL Connectez-vous pour afficher 11 to 13 Days
464,29 €
Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Mouse Target Name: FHL1 Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml Host: Rabbit Target Name: FHL1 Sample Type: Human Fetal Brain Antibody Dilution: 1.0ug/ml 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué EIA, WB 0.4 mL Connectez-vous pour afficher 8 to 10 Days
407,00 €
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-FHL1  Antibody Titration: 0.1 µg/mL ELISA Titer: 1:.12500  Positive Control: Human Muscle 100 μL Connectez-vous pour afficher 6 to 8 Days
288,68 €
Détails
Humain Lapin Inconjugué FACS, IHC (p), WB Western blot analysis of FHL1 Antibody (C-term) (ABIN390835) in NIH-3T3 cell line lysates (35 µg/lane). FHL1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human skeletal muscle reacted with FHL1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Chèvre Inconjugué IHC, ELISA, WB ABIN185289 staining (0.05µg/ml) of Human Muscle lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Connectez-vous pour afficher 3 to 4 Days
349,82 €
Détails
Humain Chèvre Inconjugué ELISA, WB ABIN185290 (0.01µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 3 to 4 Days
349,82 €
Détails
Humain Chèvre Inconjugué ELISA, WB ABIN250290 (0.01ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Connectez-vous pour afficher 3 to 5 Days
388,75 €
Détails
Humain Chèvre Inconjugué IHC (p), IHC, ELISA, WB ABIN250288 staining (0.05ug/ml) of Human Muscle lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Western Blot: FHL1 Antibody [ABIN250288] - ABIN250288 staining (0.05ug/ml) of Human Muscle lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 0.1 mg Connectez-vous pour afficher 3 to 5 Days
388,75 €
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: FHL1 Antibody [NBP1-88745] - Staining of human cell line U-251MG shows positivity in cytoplasm. Immunohistochemistry-Paraffin: FHL1 Antibody [NBP1-88745] - Staining of human skeletal muscle shows strong nuclear and cytoplasmic positivity in myocytes. 0.1 mL Connectez-vous pour afficher 6 to 9 Days
418,75 €
Détails

FHL1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Four and A Half LIM Domains 1 Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal FHL1 Primary Antibody pour IHC, WB - ABIN2775759 : McGrath, Mitchell, Coghill, Robinson, Brown: Skeletal muscle LIM protein 1 (SLIM1/FHL1) induces alpha 5 beta 1-integrin-dependent myocyte elongation. dans American journal of physiology. Cell physiology 2003 (PubMed)
    Show all 12 references for 2775759

  2. Human Polyclonal FHL1 Primary Antibody pour IHC, ELISA - ABIN185289 : Brown, McGrath, Ooms, Gurung, Maimone, Mitchell et al.: Characterization of two isoforms of the skeletal muscle LIM protein 1, SLIM1. Localization of SLIM1 at focal adhesions and the isoform slimmer in the nucleus of myoblasts and cytoplasm of myotubes ... dans The Journal of biological chemistry 1999 (PubMed)
    Show all 4 references for 185289

  3. Human Polyclonal FHL1 Primary Antibody pour ELISA, WB - ABIN250290 : Zhang, Chen, Sharma, Moon, Sheftel, Dawood, Nghiem, Wu, Li, Gramolini, Sorensen, Penninger, Brumell, Liu: HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress. dans Nature communications 2014 (PubMed)
    Show all 2 references for 250290

  4. Human Polyclonal FHL1 Primary Antibody pour IHC (p), IHC - ABIN250288 : Gramolini, Kislinger, Alikhani-Koopaei, Fong, Thompson, Isserlin, Sharma, Oudit, Trivieri, Fagan, Kannan, Higgins, Huedig, Hess, Arab, Seidman, Seidman, Frey, Perry, Backx, Liu, MacLennan, Emili: Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses. dans Molecular & cellular proteomics : MCP 2008 (PubMed)
    Show all 2 references for 250288

  5. Human Polyclonal FHL1 Primary Antibody pour ICC, IF - ABIN4311629 : Ek, Andréasson, Hober, Kampf, Pontén, Uhlén, Merz, Borrebaeck: From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies. dans Molecular & cellular proteomics : MCP 2006 (PubMed)

  6. Human Polyclonal FHL1 Primary Antibody pour FACS, IHC (p) - ABIN390835 : Gueneau, Bertrand, Jais, Salih, Stojkovic, Wehnert, Hoeltzenbein, Spuler, Saitoh, Verschueren, Tranchant, Beuvin, Lacene, Romero, Heath, Zelenika, Voit, Eymard, Ben Yaou, Bonne: Mutations of the FHL1 gene cause Emery-Dreifuss muscular dystrophy. dans American journal of human genetics 2009 (PubMed)

  7. Cow (Bovine) Polyclonal FHL1 Primary Antibody pour WB - ABIN2777486 : Rice, Kees, Greene: Transcriptional regulation of FHL1 by TLX1/HOX11 is dosage, cell-type and promoter context-dependent. dans Biochemical and biophysical research communications 2008 (PubMed)

Plus d’anticorps contre Four and A Half LIM Domains 1 partenaires d’interaction

Human Four and A Half LIM Domains 1 (FHL1) interaction partners

  1. We have uncovered FHL1 as a novel potential regulator of calcium homeostasis in both fish and humans and have implicated it in isolated hypoparathyroidism.

  2. Mutations in FHL1 cause unclassifiable cardiomyopathy with coexisting Emery-Dreifuss muscular dystrophy.

  3. results provide evidence that FHL1A interacts with PLEKHG2 (Montrer PLEKHG2 Anticorps) and regulates cell morphological change through the activity of PLEKHG2 (Montrer PLEKHG2 Anticorps).

  4. a novel FHL1 splice site variant results in the absence of FHL1A and the abundance of FHL1C, which may contribute to the complex and severe phenotype of Uruguay syndrome.

  5. Knockdown of FHL1 with FHL1 small interfering RNA (siRNA) promoted tumor growth and Cyclin D and cyclin E (Montrer CCNE1 Anticorps) were markedly elevated at both the protein and mRNA level.

  6. results indicate that anti-FHL1 autoantibodies in peripheral blood have promising potential as a biomarker to identify a subset of severe IIM.

  7. In healthy individuals, FHL1A is the predominant splice variant and is mainly found in skeletal and cardiac muscle. In two individuals with an Emery-Dreifuss plus phenotype with pulmonary artery hypoplasia and facial dysmorphology, there was demonstrated loss of isoform A and B, and an almost 200-fold overexpression of isoform C.

  8. FRG1 (Montrer FRG1 Anticorps) mice overexpressing FHL1 showed an improvement in the dystrophic phenotype

  9. FHL1 shRNA could significantly accelerate tumor cell growth via inhibiting the expression of FHL1

  10. Our results suggest that miR (Montrer MLXIP Anticorps)-410 may function as an oncomiR and are consistent with its key function in regulating FHL1 in certain digestive system cancers.

Mouse (Murine) Four and A Half LIM Domains 1 (FHL1) interaction partners

  1. KyoT2 downregulates airway remodeling and resistance in asthmatic mice through a Hes1-dependent mechanism.

  2. Results found that osteogenesis increases with the overexpression of Fhl1 and decreases with reduced Fhl1 expression and suggest that Fhl1 mediates interacting estrogen and Wnt (Montrer WNT2 Anticorps) signaling during osteogenesis.

  3. Findings indicate that loss of function is responsible for the myopathy in the Fhl1 W122S knock-in mice.

  4. The CSL (Montrer SMPX Anticorps)-KyoT2 corepressor complex is a negative regulator of Notch (Montrer NOTCH1 Anticorps) signaling.

  5. Data show that loss of FHL1 function leads to myopathy in vivo and suggest that loss of function of FHL1 may be one of the mechanisms underlying muscle dystrophy in patients with FHL1 mutations.

  6. Fhl1 transcriptional changes provide salutary effects on stressed myocytes in cardiomyopathy.

  7. Data suggest Fhl1 (four-and-a-half LIM domains protein 1) and FHL2 (four-and-a-half LIM domains protein 2 (Montrer FHL2 Anticorps)) bind to and regulate activity of Prkd1 (protein kinase D (Montrer PRKD1 Anticorps) 1) in cardiac/ventricular myocytes; knockdown of Fhl1 down-regulates Prkd1 (Montrer PRKD1 Anticorps) activation.

  8. A novel mechanism involving four-and-a-half LIM domain protein (Montrer PDLIM7 Anticorps)-1 and extracellular signal-regulated kinase-2 (Montrer MAPK1 Anticorps) regulates titin (Montrer TTN Anticorps) phosphorylation and mechanics.

  9. Wnt (Montrer WNT2 Anticorps) signaling induces muscle cell differentiation, at least partly, through Fhl1 activation.

  10. FHL1 is a novel regulator of myosin-binding (Montrer PPP1R12A Anticorps) protein C (Montrer PROC Anticorps) activity that may have a role in sarcomere assembly

Pig (Porcine) Four and A Half LIM Domains 1 (FHL1) interaction partners

  1. The LIM domain protein (Montrer PDLIM7 Anticorps) FHL1C interacts with tight junction protein ZO-1 (Montrer TJP1 Anticorps) contributing to the epithelial-mesenchymal transition of a breast adenocarcinoma cell line.

Four and A Half LIM Domains 1 (FHL1) profil antigène

Profil protéine

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.

Gene names and symbols associated with FHL1

  • four and a half LIM domains 1 (fhl1) anticorps
  • four and a half LIM domains 1 (FHL1) anticorps
  • four and a half LIM domains 1 (LOC100357263) anticorps
  • four and a half LIM domains 1a (fhl1a) anticorps
  • Four and a half LIM domains protein 1 (fhl1) anticorps
  • four and a half lim domains protein 1 (fhl1) anticorps
  • four and a half LIM domains 1 (Fhl1) anticorps
  • four and a half LIM domains 1 protein, isoform C (FHL1C) anticorps
  • DKFZp468O1927 anticorps
  • fhl anticorps
  • FHL-1 anticorps
  • Fhl1 anticorps
  • FHL1A anticorps
  • FHL1B anticorps
  • fhla anticorps
  • FLH1A anticorps
  • KyoT anticorps
  • MGC89165 anticorps
  • SLIM anticorps
  • SLIM-1 anticorps
  • SLIM1 anticorps
  • SLIMMER anticorps
  • XMPMA anticorps
  • zgc:92025 anticorps

Protein level used designations for FHL1

four and a half LIM domains 1 , four and a half LIM domains protein 1-like , four and a half LIM domains a , four and a half LIM domains protein 1 , Four and a half LIM domains protein 1 , four and a half lim domains protein 1 , LIM protein SLIMMER , four-and-a-half Lin11, Isl-1 and Mec-3 domains 1 , skeletal muscle LIM-protein 1 , FHL-1 , RAM14-1 , RBP-associated molecule 14-1 , SLIM , SLIM-1 , four and a half LIM domains 1 protein

GENE ID SPECIES
448334 Xenopus (Silurana) tropicalis
710692 Macaca mulatta
100172515 Pongo abelii
100307044 Ovis aries
100357263 Oryctolagus cuniculus
100387250 Callithrix jacchus
100590327 Nomascus leucogenys
399646 Danio rerio
100196873 Salmo salar
100529032 Ictalurus punctatus
447182 Xenopus laevis
2273 Homo sapiens
14199 Mus musculus
25177 Rattus norvegicus
509056 Bos taurus
397667 Sus scrofa
492162 Canis lupus familiaris
Fournisseurs de qualité sélectionnés pour anti-Four and A Half LIM Domains 1 (FHL1) Anticorps
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