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GPR125 encodes a member of the G protein-coupled receptor superfamily.
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Human Polyclonal GPR125 Primary Antibody pour EIA,WB - ABIN374967
Seandel, James, Shmelkov, Falciatori, Kim, Chavala, Scherr, Zhang, Torres, Gale, Yancopoulos, Murphy, Valenzuela, Hobbs, Pandolfi, Rafii: Generation of functional multipotent adult stem cells from GPR125+ germline progenitors. dans Nature 2007
ID4 (Montrer ID4 Anticorps) and GPR125 are expressed on partially overlapping spermatogonial populations and are more broadly expressed in normal adult human testis. ID4 (Montrer ID4 Anticorps) and GPR125 could be used for identifying previously unrecognized human spermatogonial subpopulations
upregulation of Gpr125 by cooperating MLL (Montrer MLL Anticorps)/AF10 (Montrer MLLT10 Anticorps)(OM-LZ) and KRASG12C promoted cell adhesion and contributed to the myeloid sarcoma formation.
GPR125+ multipotent adult stem cells generated derivatives of the three germ layers and contributed to chimaeric embryos, with concomitant downregulation of GPR125 during differentiation into GPR125- cells
Data show that GPR125 is specifically expressed in cells of the choroid plexus and is upregulated following traumatic brain injury.
This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila disc large tumor suppressor gene. This gene is mapped to a candidate region of chromosome 4 which may be associated with bipolar disorder and schizophrenia.
G protein-coupled receptor 125
, probable G-protein coupled receptor 125-like
, probable G-protein coupled receptor 125