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anti-Glutamate Receptor, Metabotropic 7 (GRM7) Anticorps

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. De plus, nous expédions GRM7 Kits (14) et GRM7 Protéines (7) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
GRM7 2917 Q14831
GRM7 108073 Q68ED2
GRM7 81672 P35400
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Top anti-GRM7 Anticorps sur anticorps-enligne.fr

Showing 10 out of 112 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IF, ELISA, WB Western blot analysis of extracts from Jurkat cells, using GRM7 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using GRM7 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails
Humain Chèvre Inconjugué WB 0.1 mg Connectez-vous pour afficher 8 to 10 Days
357,50 €
Détails
Humain Chèvre Inconjugué ELISA, WB 0.1 mg Connectez-vous pour afficher 3 to 5 Days
388,75 €
Détails
Boeuf (Vache) Lapin Inconjugué IHC (fro) Western blot of mouse brain lysate showing the specific immunolabeling of the ~102k mGluR7 protein phosphorylated at Ser862. Immunolabeling is blocked by the phospho-peptide used as antigen (peptide) but not by the corresponding dephospho-peptide (not shown). 0.1 mL Connectez-vous pour afficher 8 to 10 Days
418,00 €
Détails
Humain Lapin Inconjugué WB WB Suggested Anti-GRM7 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate WB Suggested Anti-GRM7  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control:.21_B cell lysate  GRM7 is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué EIA, IF, IHC (p), WB 0.1 mg Connectez-vous pour afficher 8 to 10 Days
385,00 €
Détails
Humain Chèvre Inconjugué ELISA, WB EB09243 (0.5µg/ml) staining of Human Cerebellum lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 3 to 4 Days
349,82 €
Détails
Boeuf (Vache) Lapin Inconjugué IHC (p), WB Immunohistochemistry-Paraffin: mGluR7 Antibody [NLS917] - Analysis of anti-GRM7 / MGLUR7 antibody with human adrenal at dilution 7 ug/ml. Immunohistochemistry-Paraffin: mGluR7 Antibody [NLS917] - Analysis of anti-GRM7 / MGLUR7 antibody with human liver at dilution 7 ug/ml. 0.05 mL Connectez-vous pour afficher 6 to 9 Days
426,25 €
Détails
Humain Lapin Inconjugué IF, IHC (p), WB Immunohistochemical staining of Brain (Neurons and Glia) using anti- GRM7 antibody ABIN122320 50 μg Connectez-vous pour afficher 8 to 10 Days
379,50 €
Détails
Humain Lapin Inconjugué ELISA, IF, IHC, WB Western Blot (WB) analysis of specific cells using mGluR-7 Polyclonal Antibody. 100 μL Connectez-vous pour afficher 13 Days
154,33 €
Détails

GRM7 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-GRM7 Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal GRM7 Primary Antibody pour IHC (fro) - ABIN784604 : Suh, Pelkey, Lavezzari, Roche, Huganir, McBain, Roche: Corequirement of PICK1 binding and PKC phosphorylation for stable surface expression of the metabotropic glutamate receptor mGluR7. dans Neuron 2008 (PubMed)
    Show all 4 references for ABIN784604

  2. Cow (Bovine) Polyclonal GRM7 Primary Antibody pour IHC (p), WB - ABIN4334140 : Friedman, Van Laer, Huentelman, Sheth, Van Eyken, Corneveaux, Tembe, Halperin, Thorburn, Thys, Bonneux, Fransen, Huyghe, Pyykkö, Cremers, Kremer, Dhooge, Stephens, Orzan, Pfister, Bille, Parving et al.: GRM7 variants confer susceptibility to age-related hearing impairment. ... dans Human molecular genetics 2009 (PubMed)
    Show all 2 references for ABIN4334140

  3. Human Polyclonal GRM7 Primary Antibody pour ELISA, WB - ABIN447400 : Vadasz, Saito, Gyetvai, Oros, Szakall, Kovacs, Prasad, Toth: Glutamate receptor metabotropic 7 is cis-regulated in the mouse brain and modulates alcohol drinking. dans Genomics 2007 (PubMed)

  4. Human Polyclonal GRM7 Primary Antibody pour IF, ELISA - ABIN1535757 : Flor, Van Der Putten, Rüegg, Lukic, Leonhardt, Bence, Sansig, Knöpfel, Kuhn: A novel splice variant of a metabotropic glutamate receptor, human mGluR7b. dans Neuropharmacology 1997 (PubMed)

Plus d’anticorps contre GRM7 partenaires d’interaction

Human Glutamate Receptor, Metabotropic 7 (GRM7) interaction partners

  1. Multiple genetic models identified 1 significant locus, GRM7, for 2 hypertension-derived traits.

  2. Study represents a genetic association test towards single variant and multi-markers interaction of GRM7 and GRM8 genes in both schizophrenia and major depressive disorders in Han Chinese population

  3. Glutamate (Montrer GRIN1 Anticorps) system genes have been associated with disease risk in recent analyses from the Psychiatric Genomics Consortium.

  4. results indicate that the GRM7 SNPs rs13353402 and rs1531939 might be associated with schizophrenia in Chinese Han population.

  5. results reported here do not support a role for GRM7 in ADHD

  6. Copy number variants at GRM7 may have a role in the etiology of bipolar disorder.

  7. For neither PCLO (Montrer PCLO Anticorps) nor GRM7 we found a more associated variant. For SLC6A4 (Montrer SLC6A4 Anticorps), we found a new SNP that showed a lower P-value than in the GAIN-MDD GWAS

  8. in an elderly male Han Chinese population, GRM7 SNP rs11928865 (TT) occurs more frequently in age-related hearing impairment patients with SL and AL phenotype patterns.

  9. These results provide preliminary evidence of an association between the GRM7 rs37952452 polymorphism and selective attention deficit and anxiety found within the Korean ADHD population

  10. Mixed modeling analyses explored the relationship of GRM7 haplotype and SNP genotypes with measures of auditory perception. GRM7 alleles are associated primarily with peripheral measures of hearing loss, and with speech detection in older adults.

Mouse (Murine) Glutamate Receptor, Metabotropic 7 (GRM7) interaction partners

  1. This study provides evidence for mGlu7 receptor-mediated tonic modulation of a physiological function in vivo preventing synchronous and potentially pathological oscillations.

  2. Analysis of mGluR7 (Montrer GRM2 Anticorps) KO mice, c-Fos expression, and cerebral MMPIP microinjection indicate that inhibition of mGluR7 (Montrer GRM2 Anticorps) impairs intermale aggression owing to information processing dysfunction within the bed nucleus of the stria terminalis

  3. muscle does not appear to require high levels of SMN (Montrer STMN1 Anticorps) above what is produced by two copies of SMN2 (Montrer SMN1 Anticorps)

  4. SAM68 (Montrer KHDRBS1 Anticorps) is a physiological regulator of SMN2 (Montrer SMN1 Anticorps) splicing in a spinal muscular atrophy mouse model.

  5. Hyperoxia treatment increased the inclusion of SMN2 (Montrer SMN1 Anticorps) exon 7 in skeletal muscles and resulted in improved motor function.

  6. Elfn1 (Montrer ELFN1 Anticorps) recruits mGluR7 (Montrer GRM2 Anticorps) to synaptic sites.A trans interaction of Elfn1 (Montrer ELFN1 Anticorps) and mGluR7 (Montrer GRM2 Anticorps) controls targeted interneuron synapse development.

  7. GRM7 regulates the phosphorylation of CREB (Montrer CREB1 Anticorps) protein and the expression of Yes-associated protein (YAP (Montrer YAP1 Anticorps)) by directly interacting with CaM (Montrer Calm2 Anticorps), which subsequently regulates the expression of CyclinD1 and ultimately affects early cortical development.

  8. Modeling the selective interaction between XAP044 and mGlu7's Venus flytrap domain, whose three-dimensional structure is already known, will facilitate future drug development supported by computer-assisted drug design

  9. The data of this study revealed very different roles for mGlu7 in amygdala synaptic transmission, fear learning and its expression

  10. These data suggest targeting mGlu7 receptors with selective antagonist drugs may be an effective and safe strategy for the treatment of anxiety disorders.

GRM7 profil antigène

Profil protéine

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GRM7

  • glutamate receptor, metabotropic 7 (GRM7) anticorps
  • metabotropic glutamate receptor 7 (MGLUR7) anticorps
  • glutamate receptor, metabotropic 7 (Grm7) anticorps
  • 6330570A01Rik anticorps
  • BB176677 anticorps
  • C030018L03 anticorps
  • E130018M02Rik anticorps
  • GLUR7 anticorps
  • Gpr1g anticorps
  • Gprc1g anticorps
  • MGLU7 anticorps
  • mGluR7 anticorps

Protein level used designations for GRM7

metabotropic glutamate receptor 7 , mGluR7 , G protein-coupled receptor GRM7 , G protein-coupled receptor, family C, group 1, member G , mGlu7a receptor , metabotropic glutamate receptor mGluR7 , metabotropic glutamate receptor subtype 7b

GENE ID SPECIES
535362 Bos taurus
100171884 Pongo abelii
443520 Ovis aries
2917 Homo sapiens
108073 Mus musculus
81672 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-GRM7 (GRM7) Anticorps
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