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Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) Kits ELISA

Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. De plus, nous expédions GNAI1 Anticorps (64) et GNAI1 Protéines (12) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
Anti-Souris GNAI1 GNAI1 14677 B2RSH2
Anti-Humain GNAI1 GNAI1 2770 P63096
Anti-Rat GNAI1 GNAI1 25686 P10824
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Plus Kits ELISA pour GNAI1 partenaires d'interaction

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) interaction partners

  1. stimulation of GPR17 (Montrer GPR17 Kits ELISA) by the small molecule agonist MDL29,951 (2-carboxy-4,6-dichloro-1H-indole-3-propionic acid) decreases myelin basic protein (Montrer MBP Kits ELISA) expression levels mainly by triggering the Galphai/o signaling pathway.

  2. Gnai1 missense mutation is responsible of hyperpigmentation in mouse model.

  3. acidosis in inflamed tissues may be a decisive factor to regulate switching of PKA and PKCepsilon dependence via proton-sensing G-protein-coupled receptors.

  4. Data show that guanine nucleotide-binding protein G(i) subunit alpha-1 and alpha-3 (Galphai1/3) can interact with CD14 antigen/Grb2-associated binding protein Gab1, which modulates macrophage polarization in vitro and in vivo.

  5. By using mice deficient in individual Galphai/o G-protein subunits, authors demonstrate that Galphai1 and Galphai3 are the critical in vivo targets of ADP-ribosylation underlying vasoactive amine sensitization elicited by pertussis toxin exposure.

  6. leucine can directly facilitate insulin (Montrer INS Kits ELISA) signaling through a Galphai protein-dependent intracellular signaling pathway

  7. Inactive Galpha(i1)-GDP enhances the affinity of RGS14 for H-Ras-GTP in live cells, resulting in a ternary signaling complex that is further regulated by G protein-coupled receptors.

  8. Mice with mutations of Gnai1 or Gnai2 (Montrer GNAI2 Kits ELISA) have neither fusions of ribs nor lumbar vertebrae, but loss of both Gnai3 (Montrer GNAI3 Kits ELISA) and one of the other two genes increases the number and severity of rib fusions without affecting the lumbar fusions.

  9. Results suggest a model in which the Gbetagamma dimer that is released as a result of the dissociation from Galpha(o (Montrer GNAO1 Kits ELISA)) upon activation of mGluR6 (Montrer GRM6 Kits ELISA) closes the TRPM1 (Montrer TRPM1 Kits ELISA) channel, perhaps via a direct interaction.

  10. RGS14 (Montrer RGS16 Kits ELISA) can form complexes with GPCRs in cells that are dependent on Galpha (Montrer SUCLG1 Kits ELISA)(i/o) and these RGS14 (Montrer RGS16 Kits ELISA).Galpha (Montrer SUCLG1 Kits ELISA)(i1).GPCR (Montrer GPBAR1 Kits ELISA) complexes may be substrates for other signaling partners such as Ric-8A (Montrer RIC8A Kits ELISA)

Human Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) interaction partners

  1. Data indicate that hydroxyurea (HU) induces SAR1 (Montrer IQGAP1 Kits ELISA) protein expression, which in turn activates gamma-globin (Montrer HBG1 Kits ELISA) expression, predominantly through the Gialpha/JNK (Montrer MAPK8 Kits ELISA)/Jun (Montrer JUN Kits ELISA) pathway.

  2. Gi alpha subunit (Montrer POLG Kits ELISA) was found to be a key modulator of GABAB-receptors signaling in analgesia.

  3. AC5, by binding active Galphai1, interferes with G-protein deactivation and reassembly and thereby might sensitize its own regulation.

  4. Data indicate that focal adhesion kinase (FAK) activation and cell migration require Src, Gi/Go, COX-2 and LOXs activities.

  5. resistin (Montrer RETN Kits ELISA) contributes to the pro-inflammatory state of SMC (Montrer DYM Kits ELISA) by the up-regulation of CX3CL1 (Montrer CX3CL1 Kits ELISA) and CX3CR1 (Montrer CX3CR1 Kits ELISA) expression via a mechanism involving NF-kB, AP-1 (Montrer FOSB Kits ELISA), and STAT1 (Montrer STAT1 Kits ELISA)/3 transcription factors, (2) resistin (Montrer RETN Kits ELISA) employs TLR4 (Montrer TLR4 Kits ELISA) and Gi-protein signaling.

  6. leucine can directly facilitate insulin (Montrer INS Kits ELISA) signaling through a Galphai protein-dependent intracellular signaling pathway

  7. Data suggest that chemokine (Montrer CCL1 Kits ELISA) binding to CCX-CKR (Montrer CCRL1 Kits ELISA) (a) recruits Gi proteins and beta-arrestin (beta-arr (Montrer SAG Kits ELISA)) with high affinity.

  8. This study support a role for RGS (Montrer PITX2 Kits ELISA) proteins as negative regulators of opioid supraspinal antinociception and also reveal a potential novel function of RGS (Montrer PITX2 Kits ELISA) proteins as positive regulators of opioid spinal antinociceptive pathways.

  9. Galpha(o (Montrer GNAO1 Kits ELISA)) protein contributes to maximally efficient mu-opioid receptor (Montrer OPRM1 Kits ELISA) signaling and antinociception in Galpha(o (Montrer GNAO1 Kits ELISA)) null transgenic mice.

  10. CXCL12 (Montrer CXCL12 Kits ELISA) signaling via CXCR7 (Montrer CXCR7 Kits ELISA) is Gialpha independent.

GNAI1 profil antigène

Antigen Summary

Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. The protein encoded by this gene represents the alpha subunit of an inhibitory complex. The encoded protein is part of a complex that responds to beta-adrenergic signals by inhibiting adenylate cyclase. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GNAI1

  • guanine nucleotide binding protein (G protein), alpha inhibiting 1 (Gnai1) anticorps
  • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (gnai1-b) anticorps
  • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (GNAI1) anticorps
  • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (Gnai1) anticorps
  • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (gnai1) anticorps
  • AU046200 anticorps
  • BPGTPB anticorps
  • Gi anticorps
  • Gialpha1 anticorps
  • Gnai-1 anticorps
  • gnai1 anticorps
  • zgc:63957 anticorps

Protein level used designations for GNAI1

adenylate cyclase-inhibiting G alpha protein , guanine nucleotide binding protein, alpha inhibiting 1 , guanine nucleotide-binding protein G(i) subunit alpha-1 , Gi1 protein alpha-subunit , alpha-subunit of G-protein, type G-alpha-i-1 , guanine nucleotide-binding protein G(i), alpha-1 subunit , Gi1 protein alpha subunit , Gi-alpha-1 protein , guanine nucleotide binding protein (G protein), alpha inhibiting 1 , Galpha i1a

GENE ID SPECIES
14677 Mus musculus
100135528 Cavia porcellus
399463 Xenopus laevis
396368 Gallus gallus
2770 Homo sapiens
397505 Sus scrofa
281790 Bos taurus
25686 Rattus norvegicus
393946 Danio rerio
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