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anti-Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) Anticorps

HEY2 encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. De plus, nous expédions HEY2 Protéines (6) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
HEY2 23493 Q9UBP5
HEY2 15214 Q9QUS4
HEY2 155430  
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Top anti-HEY2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 72 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Poulet Lapin Inconjugué WB WB Suggested Anti-HEY2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: NCI-H226 cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué IHC (p), WB HEY2 Antibody (N-term) (ABIN652095) western blot analysis in mouse heart tissue lysates (15 µg/lane). This demonstrates the HEY2 antibody detected HEY2 protein (arrow). HEY2 antibody (N-term) (ABIN652095) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Poisson Zèbre Lapin Inconjugué WB DANRE hey2 Antibody (C-term) (ABIN1881411) western blot analysis in zebra fish brain tissue lysates (35 µg/lane). This demonstrates the DANRE hey2 antibody detected the DANRE hey2 protein (arrow). 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from K562 cells, using HEY2 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails
Humain Lapin Inconjugué WB Western blot analysis of HEY2 expression in A549 (A), MCF7 (B), K562 (C) whole cell lysates. 200 μL Connectez-vous pour afficher 7 to 8 Days
464,29 €
Détails
Humain Lapin Inconjugué ELISA, WB 100 μL Connectez-vous pour afficher 11 to 14 Days
565,71 €
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
653,02 €
Détails
Boeuf (Vache) Chèvre Inconjugué ELISA   0.1 mg Connectez-vous pour afficher 3 to 5 Days
302,50 €
Détails
Humain Lapin Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 15 to 21 Days
419,39 €
Détails
Humain Chèvre Inconjugué ELISA, WB   0.1 mg Connectez-vous pour afficher 6 to 8 Days
472,74 €
Détails

HEY2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-HEY2 Anticorps mieux référencés

  1. Zebrafish (Danio rerio) Polyclonal HEY2 Primary Antibody pour WB - ABIN1881411 : Winkler, Elmasri, Klamt, Volff, Gessler: Characterization of hey bHLH genes in teleost fish. dans Development genes and evolution 2003 (PubMed)
    Show all 3 references for ABIN1881411

  2. Cow (Bovine) Polyclonal HEY2 Primary Antibody pour ELISA - ABIN4317227 : Tang, Urs, Liaw: Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site. dans Circulation research 2008 (PubMed)

Plus d’anticorps contre HEY2 partenaires d’interaction

Human Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) interaction partners

  1. Individuals with HEY2 duplications should be screened for congenital heart defects.

  2. HEY2 CC genotype may be a favorable prognostic marker for BrS, protectively acting to prevent ventricular fibrillation presumably by regulating the repolarization current.

  3. Overexpression of HEY1 (Montrer HEY1 Anticorps) and HEY2 in esophageal squamous cell carcinoma (ESCC) is correlated to different indices of poor prognosis, and it is extrapolated that such overexpression is important in progression and development of ESCC tumorigenesis.

  4. bone morphogenic proteins within the serum of cell culture medium are potent inducers of endothelial Hey1 (Montrer HEY1 Anticorps) and Hey2 gene expression within the first few hours after medium change

  5. a new HRD1 (Montrer SYVN1 Anticorps)-associated membrane protein named HERP2 (Montrer HEY1 Anticorps), which is homologous to the previously identified HRD1 (Montrer SYVN1 Anticorps) partner HERP1. Despite sequence homology, HERP2 (Montrer HEY1 Anticorps) is constitutively expressed in cells, whereas HERP1 is highly induced by ER stress.

  6. Data indicate that culture abrogated differential gene expression in part due to gradual loss of canonical Notch (Montrer NOTCH1 Anticorps) activity and HEY2 expression.

  7. Common variants at SCN5A (Montrer SCN5A Anticorps)-SCN10A (Montrer SCN10A Anticorps) and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

  8. Hey2 and COUP-TFII (Montrer NR2F2 Anticorps) have an important role in arteriovenous differentiation of human endothelial cells.

  9. Report down-regulation of Notch (Montrer NOTCH1 Anticorps) signaling components NOTCH3 (Montrer NOTCH3 Anticorps) and HEY2 in abdominal aortic aneurysms.

  10. Through activating the Dll4 (Montrer DLL4 Anticorps)-Notch (Montrer NOTCH1 Anticorps)-Hey2 signaling pathway, HGF (Montrer HGF Anticorps) indirectly promotes the proliferation and migration ability of cells, so that offspring artery branches are formed.

Mouse (Murine) Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) interaction partners

  1. Hey proteins mechanistically repress target genes via histone deacetylase (Montrer HDAC1 Anticorps) recruitment and histone deacetylation.

  2. Results suggest that bone morphogenetic protein signaling plays pivotal roles in retinal progenitor cell differentiation into late differentiating retinal cell types and in Muller glia maturation; these effects were mediated, at least in part, by Hey2

  3. Hey1 (Montrer HEY1 Anticorps) and Hey2 in endothelial cells play important roles in vascular development.

  4. findings indicate that Hey1 (Montrer HEY1 Anticorps) and Hey2 control the spatial and temporal pattern of auditory HC differentiation.

  5. CHF1/Hey2 may contribute to Brugada syndrome.

  6. Common variants at SCN5A (Montrer SCN5A Anticorps)-SCN10A (Montrer SCN10A Anticorps) and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.

  7. Data indicate that Hairy and Enhancer of Split-related with YRPW motif (HEY)2 decreases skeletal mass and regulates bone remodeling in male mice.

  8. Data indicate that Notch1 (Montrer NOTCH1 Anticorps) and Notch2 (Montrer NOTCH2 Anticorps) are expressed and localized in the nuclei of the label-retaining cells (LRCs), and the expression of Notch (Montrer NOTCH1 Anticorps)-inducible genes, Hes1 and Hey2, was elevated in LRCs.

  9. Survivor mice lacking the Hesr2 gene exhibit fibrosis in the aortic valve and ventricle in adulthood, thus suggesting that Hesr2 plays an important role in maintaining the homeostasis of the aortic valve and ventricle.

  10. Transcription factor CHF1/Hey2 regulates EC coupling and heart failure in mice through regulation of FKBP12.6 (Montrer FKBP1B Anticorps).

Zebrafish Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) interaction partners

  1. essential role for Hey2 upstream of Notch in hematopoietic stem cell formation

  2. Forms a complex with Gata5 through the carboxyl region and can repress Gata5-mediated transcription.

  3. The snrk (Montrer SNRK Anticorps)-1 gene acts downstream or parallel to notch (Montrer NOTCH1 Anticorps) and upstream of gridlock during artery-vein specification

HEY2 profil antigène

Profil protéine

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.

Gene names and symbols associated with HEY2

  • hairy/enhancer-of-split related with YRPW motif 2 (HEY2) anticorps
  • hairy/enhancer-of-split related with YRPW motif 2 (Hey2) anticorps
  • hairy/enhancer-of-split related with YRPW motif 2 (hey2) anticorps
  • bHLHb32 anticorps
  • CHF1 anticorps
  • GRIDLOCK anticorps
  • grl anticorps
  • Herp1 anticorps
  • hesr2 anticorps
  • Hrt2 anticorps
  • zgc:136746 anticorps

Protein level used designations for HEY2

hairy/enhancer-of-split related with YRPW motif protein 2 , HES-related repressor protein 1 , HES-related repressor protein 2 , HESR-2 , HRT-2 , cardiovascular basic helix-loop-helix factor 1 , cardiovascular helix-loop-helix factor 1 , class B basic helix-loop-helix protein 32 , hCHF1 , hHRT2 , hairy and enhancer of split-related protein 2 , hairy-related transcription factor 2 , protein gridlock homolog , Hairy-E(spl)-related with YRPW motif 2 , hairy and enhancer of split related 2 , mHRT2 , Herp2 , gridlock , protein gridlock

GENE ID SPECIES
100152404 Sus scrofa
23493 Homo sapiens
15214 Mus musculus
58146 Danio rerio
484115 Canis lupus familiaris
538619 Bos taurus
155430 Rattus norvegicus
421718 Gallus gallus
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