anti-Heat Shock 70kDa Protein 8 (HSPA8) Anticorps

HSPA8 encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. De plus, nous expédions HSPA8 Kits (27) et HSPA8 Protéines (27) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
HSPA8 3312 P11142
Anti-Rat HSPA8 HSPA8 24468 P63018
HSPA8 15481 P63017
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Top anti-HSPA8 Anticorps sur anticorps-enligne.fr

Showing 10 out of 268 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB <b>WB Suggested Anti-HSPA8 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>293T cell lysate <b>Sample type:</b> rat brain lysate<br><b>Primary Dilution: </b>1:1000<br><b>Image Submitted By:</b> Jennifer Morgan, PhD &, David Busch<br>University of Texas in Austin 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Chévre Lapin Inconjugué IHC, WB <b>WB Suggested Anti-HSPA8 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>COLO205 cell lysate <b>Sample Type:</b> 1. Lamprey CNS (20ug)<br>2. Rat Brain Lysate (20ug) <br><b>Primary Dilution: </b>1:1000<br><b>Secondary Antibody: </b>Goat anti-Rabbit HRP<br><b>Secondary Dilution:</b> 1:4000<br><b>Image Submitted by: </b>Jennifer Morgan, PhD &, David Busch<br>University of Texas in Austin 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Poulet Lapin Inconjugué IC, IF, IP, WB Immunofluorescent analysis of HSC70 staining in NIH3T3 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of HSC70 expression in HeLa (A), NIH3T3 (B) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué FACS, IF, IHC (p), WB Formalin-fixed and paraffin-embedded human brain tissue reacted with HSPA8 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of HSPA8 Antibody (N-term) (ABIN650754) in Hela cell line lysates (35 µg/lane). HSPA8 (arrow) was detected using the purified polyclonal antibody. 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Chèvre Inconjugué ELISA, WB NB100- (2?g/ml) staining of A431 cell lysate (35?g protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Western Blot: HSPA8/HSC71/Hsc70 Antibody [ABIN1885497] - Analysis of HSPA8 in A431 cell lysate using this antibody at 2 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Connectez-vous pour afficher 7 to 9 Days
$408.19
Détails
Humain Lapin Inconjugué IHC (p), WB 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Humain Chèvre Inconjugué ELISA, WB ABIN185659 (2µg/ml) staining of A431 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$326.89
Détails
Humain Souris Inconjugué AA, Bind, ELISA, ICC, IF, IHC, IP, PLA, WB Hsc70 (1F2 H5) human cell line mix copy. 50 μg Connectez-vous pour afficher 2 to 3 Days
$220.00
Détails
Chien Chèvre Inconjugué EIA, WB   0.1 mg Connectez-vous pour afficher 12 to 15 Days
$375.38
Détails
REACT_Artemia sp. Souris Inconjugué IF, IHC (fro), IP, WB   0.2 mg Connectez-vous pour afficher 10 to 12 Days
$375.38
Détails

HSPA8 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-HSPA8 Anticorps mieux référencés

  1. Hamster Polyclonal HSPA8 Primary Antibody pour BI, ICC - ABIN361819 : Boorstein, Ziegelhoffer, Craig: Molecular evolution of the HSP70 multigene family. dans Journal of molecular evolution 1994 (PubMed)
    Show all 13 Pubmed References

  2. Human Monoclonal HSPA8 Primary Antibody pour AA, Bind - ABIN361800 : Bork, Sander, Valencia: An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins. dans Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 10 Pubmed References

  3. Human Polyclonal HSPA8 Primary Antibody pour FACS, IF - ABIN1944844 : Tsukahara, Yoshioka, Muraki: Molecular and functional characterization of HSC54, a novel variant of human heat-shock cognate protein 70. dans Molecular pharmacology 2000 (PubMed)
    Show all 2 Pubmed References

  4. Fish Polyclonal HSPA8 Primary Antibody pour WB - ABIN361860 : Brown, Hong-Brown, Doxsey, Welch: Molecular chaperones and the centrosome. A role for HSP 73 in centrosomal repair following heat shock treatment. dans The Journal of biological chemistry 1996 (PubMed)
    Show all 6 Pubmed References

  5. Human Polyclonal HSPA8 Primary Antibody pour ELISA, WB - ABIN188549 : Zhang, Fan, Becker, Graff, Lee, Francomano: Comparison of gene expression profile between human chondrons and chondrocytes: a cDNA microarray study. dans Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2006 (PubMed)

Plus d’anticorps contre HSPA8 partenaires d’interaction

Xenopus laevis Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. hsp72 (Montrer HSPA1A Anticorps) was more potent than hsc73 in generating protective immune responses against the class Ia-negative 15/0 tumors.

Human Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Synapsin is part of a multiprotein complex enriched in chaperones/cochaperones including Hsc70. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin.

  2. study demonstrates a critical role of Hsc70 in SV40 endoplasmic reticulum-to-cytosol penetration and reveal how SGTA (Montrer SGTA Anticorps) controls Hsc70 to impact this process

  3. In fact, DnaJC5 (Montrer DNAJC5 Anticorps) overexpression induced tau release in cells, neurons, and brain tissue, but only when activity of the chaperone Hsc70 was intact and when tau was able to associate with this chaperone.

  4. HSPA1A (Montrer HSPA1A Anticorps) and HSPA8 have roles in parturition through stimulating immune inflammatory and estrogen response

  5. These results suggest that Bag1 (Montrer BAG1 Anticorps) and Bag3 (Montrer BAG3 Anticorps) control the stability of the Hsc70-client complex using at least two distinct protein-protein contacts, providing a previously under-appreciated layer of molecular regulation in the human Hsc70 system.

  6. While cerebrospinal fluid Nrf2 (Montrer GABPA Anticorps) and HSPA8 do not appear to offer diagnostic biomarkers for Parkinson's disease (PD), the associations between Nrf2 (Montrer GABPA Anticorps) levels and UPDRS scores in LRRK2 (Montrer LRRK2 Anticorps) + PD patients merit further investigation

  7. HSPA8 maintains pluripotency of human pluripotent stem cells by binding to the master pluripotency regulator OCT4 (Montrer POU5F1 Anticorps) and facilitating its DNA-binding activity.

  8. heat shock cognate 70 (HSC70) is an essential component of Aes (Montrer AES Anticorps) foci in colorectal cancer cells.

  9. Cx43 (Montrer GJA1 Anticorps)-Hsc70 interaction regulates cell cycle G1/S progression through a novel mechanism by which Cx43 (Montrer GJA1 Anticorps)-Hsc70 interaction prevents the nuclear accumulation of p27 (Montrer PAK2 Anticorps) through controlling the nuclear translocation of cyclin D1 (Montrer CCND1 Anticorps)-CDK4 (Montrer CDK4 Anticorps)-p27 (Montrer PAK2 Anticorps) complex.

  10. serum HSC71 was identified as a novel serum biomarker of renal cell carcinoma (Montrer MOK Anticorps), particularly useful in early diagnosis of clear-cell type.

Cow (Bovine) Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Single-particle fluorescence imaging tracks the dynamics of Hsc70 and its clathrin substrate in real time.

  2. The interaction of the molecular chaperone (Montrer HSP90AA1 Anticorps) Hsc70 (HSPA8) with recombinant PrP (Montrer PRNP Anticorps) was investigated.

  3. Structure of clathrin coat with bound Hsc70 and auxilin (Montrer DNAJC6 Anticorps).

  4. specific association between HSP73 and gentamicin may reduce the chaperone activity of HSP73 in vitro and/or in vivo

  5. report role of HSC70 in the regulation of NMT

  6. studied the process of disassembly by using cryo-electron microscopy to identify the initial binding site of Hsc70 on clathrin-C58J baskets at pH 6, under which conditions disassembly does not proceed further. Hsc70 interactions involve two sites

  7. Coats assembled from recombinant clathrin are good substrates for ATP- and auxilin (Montrer DNAJC6 Anticorps)-dependent, Hsc70-catalyzed uncoating.

  8. The structure of an Hsp110 (Montrer HSPH1 Anticorps):Hsc70 nucleotide exchange complex, is reported.

  9. analysis of the formation of a stable complex between chaperonin-containing TCP-1 (Montrer CCT6A Anticorps) (CCT (Montrer TCP1 Anticorps)) and Hsc70

  10. Elevated expression of bovine heat shock cognate (hsc)70 protein increases diabetes and inflammation following islet beta cell damage in a transgenic mouse model.

Mouse (Murine) Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Synapsin is part of a multiprotein complex enriched in chaperones/cochaperones including Hsc70. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin.

  2. Hsc70 interacts with FILIP to mediate its effects on non-muscle myosin IIb (Montrer MYH10 Anticorps) and to regulate spine morphology

  3. HSPA1A (Montrer HSPA1A Anticorps) and HSPA8 have roles in parturition through stimulating immune inflammatory and estrogen response

  4. intracellular Salmonella recruit the host proteins LAMP-2A and Hsc73, key components of the host protein turnover pathway known as chaperone-mediated autophagy involved in transport of cytosolic proteins to the lysosome for degradation.

  5. these data demonstrate a novel interaction between Hsc70 and TH that regulates the activity and localization of the enzyme to synaptic vesicles, suggesting an important role for Hsc70 in dopamine homeostasis.

  6. C terminus of the hsc-70 LID domain as the structural interface interacting with endosomal Phosphatidylserine

  7. the association of MNSFbeta (Montrer FAU Anticorps) with HSPA8 may promote RANKL (Montrer TNFSF11 Anticorps)-induced osteoclastogenesis.

  8. Hspa8 plays a vital role in genetic differences in responses to stress and ethanol and their interactions

  9. PTEN-like domains of GAK and auxilin are not essential for Hsc70-dependent chaperoning and uncoating of clathrin, but depending on the tissue, these domains appear to increase the efficiency of these co-chaperones.

  10. mass spectrometry-based proteomic analysis identified heat shock cognate 70 (HSC70) as a novel binding protein of FSP27 (Montrer CIDEC Anticorps)

HSPA8 profil antigène

Profil protéine

This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HSPA8

  • heat shock 70kDa protein 8 (hspa8) anticorps
  • heat shock 70kDa protein 8 (HSPA8) anticorps
  • heat shock 70kDa protein 8 (Hspa8) anticorps
  • heat shock protein 8 (Hspa8) anticorps
  • heat shock protein 8 (hspa8) anticorps
  • 2410008N15Rik anticorps
  • HSC54 anticorps
  • Hsc70 anticorps
  • Hsc71 anticorps
  • Hsc73 anticorps
  • HSP71 anticorps
  • Hsp73 anticorps
  • Hspa10 anticorps
  • LAP1 anticorps
  • NIP71 anticorps
  • wu:fb01g06 anticorps
  • wu:fi48b06 anticorps

Protein level used designations for HSPA8

LPS-associated protein 1 , N-myristoyltransferase inhibitor protein 71 , constitutive heat shock protein 70 , heat shock 70kd protein 10 , heat shock cognate 71 kDa protein , heat shock cognate protein 54 , lipopolysaccharide-associated protein 1 , Hsc70 ATPase , heat shock 70 kDa protein 8 , heat shock 70kd protein 10 (HSC71) , heat shock cognate 71 kD protein , Heat shock cognate protein 70 , heat shock 70kD protein 8 , heat shock protein 8 , heat shock protein A8 , heat shock cognate 70 , heat shock cognate 71 kDa protein-like protein , heat shock protein 70 cognate , heat shock cognate hsc73 , heat shock protein cognate 70 , heat shock 70kDa protein 8 , heat shock cognate 71-kd protein

GENE ID SPECIES
379319 Xenopus laevis
3312 Homo sapiens
281831 Bos taurus
24468 Rattus norvegicus
395853 Gallus gallus
479406 Canis lupus familiaris
100009679 Equus caballus
100172711 Pongo abelii
15481 Mus musculus
573376 Danio rerio
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