anti-Hematopoietic Cell Signal Transducer (HCST) Anticorps

HCST encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. De plus, nous expédions HCST Kits (5) et HCST Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
HCST 10870 Q9UBK5
HCST 23900 Q9QUJ0
HCST 474146 Q6X9T8
Comment commander chez anticorps-enligne
  • +33 (0)1 76 63 32 65
  • +33 (0)1 74 18 08 22
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top anti-HCST Anticorps sur anticorps-enligne.fr

Showing 10 out of 31 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Chèvre Inconjugué ELISA, WB ABIN334384 (0.2µg/ml) staining of human spleen lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 3 to 4 Days
349,82 €
Détails
Humain Chèvre Inconjugué ELISA, WB ABIN188679 (0.2?g/ml) staining of Human Spleen lysate (35?g protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: HCST Antibody [ABIN1886793] - (0.2ug/ml) staining of human spleen lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Connectez-vous pour afficher 3 to 5 Days
388,75 €
Détails
Humain Chèvre Inconjugué EIA, WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
357,50 €
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Paraformaldehyde-fixed, paraffin embedded rat spleen tissue, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with HCST Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining. 100 μL Connectez-vous pour afficher 18 to 22 Days
304,36 €
Détails
Humain Chèvre Inconjugué ELISA 100 μg Connectez-vous pour afficher 11 to 14 Days
722,86 €
Détails
Humain Chèvre Inconjugué ELISA, WB 0.1 mg Connectez-vous pour afficher 6 to 8 Days
505,48 €
Détails
Humain Lapin Cy7 IF (p)   100 μL Connectez-vous pour afficher 9 to 12 Days
414,64 €
Détails
Humain Lapin Alexa Fluor 555 IF (p)   100 μL Connectez-vous pour afficher 9 to 12 Days
414,64 €
Détails
Humain Lapin Cy3 IF (p)   100 μL Connectez-vous pour afficher 9 to 12 Days
414,64 €
Détails
Humain Lapin FITC IF (p)   100 μL Connectez-vous pour afficher 9 to 12 Days
414,64 €
Détails

HCST Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human , ,
,

, , , , , , , , , , , , , , , ,
Mouse (Murine)


Rat (Rattus)


anti-HCST Anticorps mieux référencés

  1. Human Polyclonal HCST Primary Antibody pour ELISA, WB - ABIN188679 : Upshaw, Arneson, Schoon, Dick, Billadeau, Leibson: NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells. dans Nature immunology 2006 (PubMed)

Plus d’anticorps contre HCST partenaires d’interaction

Zebrafish Hematopoietic Cell Signal Transducer (HCST) interaction partners

  1. The structure of the adaptor protein dap10 has been identified in the zebrafish genome.

Human Hematopoietic Cell Signal Transducer (HCST) interaction partners

  1. These results suggest that NKG2D (Montrer KLRK1 Anticorps)-DAP10 endocytosis represents a means to decrease cell surface receptor abundance, as well as to control signaling outcome in cytotoxic lymphocytes.

  2. findings indicate that the functional interaction between RAGE (Montrer AGER Anticorps) and DAP10 coordinately regulates S100A8 (Montrer S100A8 Anticorps)/A9-mediated survival and/or apoptotic response of keratinocytes

  3. TGF-beta1 (Montrer TGFB1 Anticorps) may reduce the expression of NKG2D (Montrer KLRK1 Anticorps)/DAP10 and 2B4 (Montrer CD244 Anticorps)/SAPin patients with hepatitis B.

  4. HMBOX1 (Montrer HMBOX1 Anticorps) negatively regulates the expression of NKG2D (Montrer KLRK1 Anticorps) and the activation of the NKG2D (Montrer KLRK1 Anticorps)/DAP10 signaling pathway in NK cells.

  5. Other gamma(c) cytokines act similarly to IL-2 (Montrer IL2 Anticorps) in up-regulating DAP10 expression and NKG2D (Montrer KLRK1 Anticorps)-DAP10 surface expression.

  6. TGF-BETA1 (Montrer TGFB1 Anticorps) down-modulates surface NKG2D (Montrer KLRK1 Anticorps) expression by controlling the transcriptional and translational levels of DAP10.

  7. A transgenic mouse model demonstrates that induction of tolerance in Ly49H (Montrer KLRA8 Anticorps)-positive natural killer (NK) cells by chronic exposure to virus-encoded ligand m157 requires signaling through the Ly49H (Montrer KLRA8 Anticorps) adaptor protein DAP12 (Montrer TYROBP Anticorps), not the DAP10 adaptor protein.

  8. NKG2D (Montrer KLRK1 Anticorps)-DAP10 triggers human NK cell-mediated killing via a Syk (Montrer SYK Anticorps)-independent regulatory pathway.

  9. both activated and expanded CD8 (Montrer CD8A Anticorps)+ T cells and NK cells use DAP10 for cytolysis

  10. Downstream targets of DAP10 and DAP12 (Montrer TYROBP Anticorps) are constitutively activated in large granular lymphocyte leukemia cells, and expression of dominant-negative DAP10 and DAP12 (Montrer TYROBP Anticorps) dramatically reduces their lytic capacity.

Mouse (Murine) Hematopoietic Cell Signal Transducer (HCST) interaction partners

  1. Adoptive transfer of murine T cells expressing a chimeric-PD1 (Montrer PDCD1 Anticorps)-Dap10 receptor may induce a preferential cytokine profile and T-cell differentiation phenotype for anti-lymphoma therapies.

  2. Rat and mouse CD94 (Montrer KLRD1 Anticorps)/NKG2C (Montrer KLRC2 Anticorps) heterodimers bind efficiently to both DAP12 (Montrer TYROBP Anticorps) and DAP10; this binding is critically dependent on the transmembrane lysine residue of CD94 (Montrer KLRD1 Anticorps).

  3. contributes to CD8 (Montrer CD8A Anticorps)(+) T cell-mediated cytotoxic effector mechanisms during Mycobacterium tuberculosis infection

  4. demonstrate a previously uncharacterized interaction of SHIP1 (Montrer INPP5D Anticorps) with DAP12 (Montrer TYROBP Anticorps) that limits TREM2 (Montrer TREM2 Anticorps)- and DAP12 (Montrer TYROBP Anticorps)-dependent signaling and identify a mechanism through which SHIP1 (Montrer INPP5D Anticorps) regulates key ITAM-containing receptors by blocking the binding and activation of PI3K

  5. selective associations with DAP10 determine stimulatory versus costimulatory activity of NKG2D (Montrer KLRK1 Anticorps)

  6. Differential requirements for Vav (Montrer VAV1 Anticorps) proteins in DAP10- and ITAM-mediated NK cell cytotoxicity.

  7. The importance of Fcgr3 (Montrer CD16 Anticorps)/Cd3z (Montrer CD247 Anticorps), Hcst, and Tyrobp (Montrer TYROBP Anticorps) in the activation of NK cells in the uterus of pregnant mice is reported.

  8. Review of immune reactions against syngeneic tumors reveals an important physiological role of DAP10 adapter protein (Montrer GRB10 Anticorps) signaling in maintaining tolerance to self, by controlling the development and activation threshold of autoreactive T cells.

  9. DAP10 signaling is involved in adjusting the activation threshold and generation of natural killer T cells and regulatory T cells to avoid autoreactivity, but it also modulates antitumor mechanisms.

  10. improved rejection of B16 melanomas in DAP10-deficient mice

Cow (Bovine) Hematopoietic Cell Signal Transducer (HCST) interaction partners

HCST profil antigène

Profil protéine

This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms.

Gene names and symbols associated with HCST

  • hematopoietic cell signal transducer (HCST) anticorps
  • hematopoietic cell signal transducer (hcst) anticorps
  • hematopoietic cell signal transducer (Hcst) anticorps
  • Dap10 anticorps
  • HCST anticorps
  • KAP10 anticorps
  • PIK3AP anticorps

Protein level used designations for HCST

hematopoietic cell signal transducer , dap10 , DNAX-activation protein 10 , kinase assoc pro of ~10kDa , kinase assoc protein , membrane protein DAP10 , phosphoinositide-3-kinase adaptor protein , transmembrane adapter protein KAP10 , putative membrane adaptor molecule , immunoreceptor DAP10

GENE ID SPECIES
612627 Canis lupus familiaris
748082 Pan troglodytes
100101460 Danio rerio
10870 Homo sapiens
23900 Mus musculus
474146 Rattus norvegicus
767892 Bos taurus
397267 Sus scrofa
574152 Macaca mulatta
Fournisseurs de qualité sélectionnés pour anti-HCST (HCST) Anticorps
Avez-vous cherché autre chose?