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Members of the Ikaros (ZNFN1A1\; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development.[supplied by OMIM, Jul 2002].. De plus, nous expédions IKZF4 Anticorps (41) et IKZF4 Protéines (4) et beaucoup plus de produits pour cette protéine.
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this study reports that IL-6 actively suppressed Eos mRNA and protein expression through miR-17
Ikaros (Montrer IKZF1 Kits ELISA) may not be a conventional activator or repressor of defined sets of genes, but may sharpen the dynamic range of gene expression changes during developmental transitions
Eos is redundant for regulatory T cell function but plays an important role in IL-2 (Montrer IL2 Kits ELISA) and IL-17 (Montrer IL17A Kits ELISA) production by CD4 (Montrer CD4 Kits ELISA)+ conventional T cells.
Data indicate that miR-17 promotes TH17 differentiation by repressing target Ikaros Family Zinc Finger 4 (IKZF4).
We show that reprogramming is controlled by downregulation of the transcription factor Eos (Ikzf4), an obligate corepressor for Foxp3 (Montrer FOXP3 Kits ELISA).
Data suggest that Eos, MITF (Montrer MITF Kits ELISA), and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitor cells.
study identified Eos as a critical mediator of Foxp3 (Montrer FOXP3 Kits ELISA)-dependent gene silencing in CD4 (Montrer CD4 Kits ELISA)+ regulatory T cells (Tregs); Eos interacts directly with Foxp3 (Montrer FOXP3 Kits ELISA) and induces chromatin modifications that result in gene silencing in Tregs
IKZF4 polymorphism (rs1701704) was strongly associated with insulin (Montrer INS Kits ELISA) autobody positivity at the time of type 1 diabetes diagnosis
Members of the Ikaros (ZNFN1A1\; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development.
ikaros family zinc finger protein 4
, zinc finger protein Eos
, zinc finger protein, subfamily 1A, 4 (Eos)
, zinc finger protein, subfamily 1A, 4
, zinc finger transcription factor Eos