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anti-Immediate Early Response 3 (IER3) Anticorps

IER3 functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. De plus, nous expédions Immediate Early Response 3 Protéines (6) et Immediate Early Response 3 Kits (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
IER3 8870 P46695
IER3 15937  
IER3 294235  
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Top anti-Immediate Early Response 3 Anticorps sur anticorps-enligne.fr

Showing 10 out of 44 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué FACS, IF, IHC (p), WB IER3 Antibody (N-term)  western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the IER3 antibody detected the IER3 protein (arrow). IER3 Antibody (N-term)  western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the IER3 antibody detected the IER3 protein (arrow). 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Lapin Inconjugué EIA, FACS, IF, IHC (p), WB Flow cytometric analysis of A549 cells using IER3 / IEX1 Antibody (N-term) Cat.-No AP52148PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of IER3 / IEX1 Antibody (N-term) Cat.-No AP52148PU-N with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 0.4 mL Connectez-vous pour afficher 8 to 10 Days
418,00 €
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB Immunohistochemistry of IEX-1 in human liver tissue with IEX-1 antibody at 2.5 μg/ml. Western blot analysis of IEX1 in human brain tissue lysate with AP30400PU-N IEX1 antibody at (A) 2 and (B) 4 μg/ml. 0.1 mg Connectez-vous pour afficher 8 to 10 Days
357,50 €
Détails
Humain Lapin Inconjugué IHC (p), WB 50 μg Connectez-vous pour afficher 8 to 10 Days
517,00 €
Détails
Humain Lapin Inconjugué IHC (p), WB Human Adrenal (formalin-fixed, paraffin-embedded) stained with IER3 antibody ABIN213935 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 11 to 14 Days
501,70 €
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-IEX1/Differentiation Dependent Gene 2 protein Polyclonal Antibody, Unconjugated (ABIN872466) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Connectez-vous pour afficher 5 to 7 Days
277,90 €
Détails
Humain Lapin Inconjugué IHC, ELISA, WB   100 μg Connectez-vous pour afficher 12 to 16 Days
412,82 €
Détails
Humain Lapin Alkaline Phosphatase (AP) FACS, ICC, IHC, ELISA, WB   200 μL Connectez-vous pour afficher 11 to 14 Days
1.019,69 €
Détails
Humain Lapin Alexa Fluor 594 IF (p)   100 μL Connectez-vous pour afficher 14 to 17 Days
366,11 €
Détails
Humain Lapin Inconjugué IHC (p), WB 50 μg Connectez-vous pour afficher 8 to 10 Days
456,00 €
Détails

IER3 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité
Human , , , ,

Mouse (Murine) , , , ,

Rat (Rattus) , ,

anti-Immediate Early Response 3 Anticorps mieux référencés

  1. Human Polyclonal IER3 Primary Antibody pour IHC, ELISA - ABIN1002470 : Kondratyev, Chung, Jung: Identification and characterization of a radiation-inducible glycosylated human early-response gene. dans Cancer research 1996 (PubMed)
    Show all 4 references for ABIN1002470

  2. Human Polyclonal IER3 Primary Antibody pour EIA, IHC (p) - ABIN499960 : Wu, Ao, Prasad, Wu, Schlossman: IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival. dans Science (New York, N.Y.) 1998 (PubMed)
    Show all 4 references for ABIN499960

  3. Human Polyclonal IER3 Primary Antibody pour FACS, IF - ABIN655735 : Fellay, Ge, Shianna, Colombo, Ledergerber, Cirulli, Urban, Zhang, Gumbs, Smith, Castagna, Cozzi-Lepri, De Luca, Easterbrook, Günthard, Mallal, Mussini, Dalmau, Martinez-Picado, Miro, Obel, Wolinsky, Martinson, Detels, Margolick, Jacobson, Descombes, Anton: Common genetic variation and the control of HIV-1 in humans. dans PLoS genetics 2009 (PubMed)
    Show all 3 references for ABIN655735

  4. Human Polyclonal IER3 Primary Antibody pour EIA, FACS - ABIN952818 : Ouakaa-Kchaou, Elloumi, Kochlef, Gargouri, Kharrat, Kilani, Ghorbel: Ovarian Crohn's disease. dans Journal of Crohn's & colitis 2010 (PubMed)
    Show all 2 references for ABIN952818

Plus d’anticorps contre Immediate Early Response 3 partenaires d’interaction

Human Immediate Early Response 3 (IER3) interaction partners

  1. interleukin-1beta (IL-1beta (Montrer IL1B Anticorps))-induced IER3 expression is mediated by the ERK1/2 (Montrer MAPK1/3 Anticorps) target, transcription factor Elk-1 (Montrer ELK1 Anticorps).

  2. findings suggest that IER3 is a putative tumor suppressor in the cervix, and the c-Ab1/p73beta/IER3 axis is a novel and crucial signaling pathway that confers etoposide chemosensitivity.

  3. High expression of IER3 is associated with hepatocarcinoma.

  4. In human samples removed from failed AVF, there was a significant increase in IEX-1 expression localized to the adventitia.

  5. IEX-1 expression levels correlate with the severity of preeclampsia

  6. Studied the binding effect of hcmv-miR (Montrer MLXIP Anticorps)-UL148D to the 3' untranslated region (3'UTR (Montrer UTS2R Anticorps)) of IEX-1.Results showed that only one binding site in the 3'UTR (Montrer UTS2R Anticorps) of IEX-1 was completely complementary to an 11nt sequence in the 5' terminus of hcmv-mir (Montrer MLXIP Anticorps)-UL148D.

  7. the interference of IER3 with the PI3K (Montrer PIK3CA Anticorps)/Akt (Montrer AKT1 Anticorps)-Fyn (Montrer FYN Anticorps) pathway represents a novel mechanism of Nrf2 (Montrer GABPA Anticorps) regulation that may get lost in tumors and by which IER3 exerts its stress-adaptive and tumor-suppressive activity.

  8. IEX-1 plays a role in suppression of apoptosis and protects cells by controlling sensitivity to TNFalpha (Montrer TNF Anticorps) under both normal and inflammatory conditions.

  9. Altered IEX-1 expression can potentially be a new predictor of the malignant transformation and a prognostic indicator for cancer therapy.

  10. Changes of methylation status of gene IEX-1 promoter CpG island correlates with hematologic malignancies.

Mouse (Murine) Immediate Early Response 3 (IER3) interaction partners

  1. these results indicate that IER3 is a key player in expanding the pool of APC (Montrer APC Anticorps) while highlighting the role of distinct effectors found in an obese microenvironment in this process

  2. Loss of IEX-1 results in reduced VNH accompanied with a decrease in proliferation, reduced fibroblast, myofibroblast, and Ly6C staining accompanied with increased apoptosis mediated through a reduction in Vegf-A (Montrer VEGFA Anticorps)/Mcp-1 (Montrer CPT1B Anticorps) axis and Mmp-9 (Montrer MMP9 Anticorps).

  3. IER3 supports KRASG12D-associated oncogenesis in the pancreas by sustaining ERK1/2 (Montrer MAPK1/3 Anticorps) phosphorylation via phosphatase PP2A (Montrer PPP2R2B Anticorps) inhibition.

  4. Stress-induced hematopoietic failure in the absence of immediate early (Montrer JUN Anticorps) response gene X-1 (IEX-1, IER3).

  5. the interference of IER3 with the PI3K/Akt (Montrer AKT1 Anticorps)-Fyn (Montrer FYN Anticorps) pathway represents a novel mechanism of Nrf2 (Montrer NFE2L2 Anticorps) regulation that may get lost in tumors and by which IER3 exerts its stress-adaptive and tumor-suppressive activity.

  6. IEX-1 has a role in activation of Erk (Montrer EPHB2 Anticorps) and NF-kB pathways, which affects thrombopoietin (Montrer THPO Anticorps)-promoted NHEJ DNA repair in hematopoietic stem cells

  7. Data suggest a role for the immediate early (Montrer JUN Anticorps) response gene X-1 (IEX-1) in the control of colon epithelial homeostasis.

  8. Our present investigation shows that null mutation of IEX-1 promotes differentiation of Th17 cells but compromises the survival of Th1 (Montrer HAND1 Anticorps) cells

  9. IER3 plays a complex and to some extent contradictory role in cell cycle control and apoptosis. Effects of IER3 relate to an interference with certain signalling pathways

  10. Mcl-1 (Montrer MCL1 Anticorps) translocation to the nucleus is a general response to genotoxic stress that is strictly and timely controlled by IEX-1 in response to DNA damage. Loss of IEX-1 leads to genomic instability.

Immediate Early Response 3 (IER3) profil antigène

Profil protéine

This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein.

Gene names and symbols associated with IER3

  • immediate early response 3 (IER3) anticorps
  • immediate early response 3 (Ier3) anticorps
  • AI663993 anticorps
  • cI-3 anticorps
  • DIF-2 anticorps
  • Dif2 anticorps
  • gly96 anticorps
  • IER3 anticorps
  • IEX-1 anticorps
  • IEX-1L anticorps
  • Iex1 anticorps
  • Ler3 anticorps
  • Prg1 anticorps

Protein level used designations for IER3

immediate early response 3 , radiation-inducible immediate-early gene IEX-1 , ATP-binding cassette, sub-family F (GCN20), member 1 , PACAP-responsive gene 1 protein , anti-death protein , differentiation-dependent gene 2 protein , expressed in pancreatic carcinoma , gly96, mouse, homolog of , immediate early protein GLY96 , immediate early response 3 protein , immediately early gene X-1 , protein DIF-2 , cAMP inducible gene 3

GENE ID SPECIES
481708 Canis lupus familiaris
505455 Bos taurus
701939 Macaca mulatta
743437 Pan troglodytes
8870 Homo sapiens
15937 Mus musculus
294235 Rattus norvegicus
462547 Pan troglodytes
Fournisseurs de qualité sélectionnés pour anti-Immediate Early Response 3 (IER3) Anticorps
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