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Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. De plus, nous expédions Integrin beta 4 Kits (24) et Integrin beta 4 Protéines (9) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 367 products:
Human Monoclonal Integrin beta 4 Primary Antibody pour IF, WB - ABIN968433
Mainiero, Pepe, Wary, Spinardi, Mohammadi, Schlessinger, Giancotti: Signal transduction by the alpha 6 beta 4 integrin: distinct beta 4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes. dans The EMBO journal 1995
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Mouse (Murine) Monoclonal Integrin beta 4 Primary Antibody pour FACS - ABIN120280
Kennel, Foote, Falcioni, Sonnenberg, Stringer, Crouse, Hemler: Analysis of the tumor-associated antigen TSP-180. Identity with alpha 6-beta 4 in the integrin superfamily. dans The Journal of biological chemistry 1989
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Mouse (Murine) Monoclonal Integrin beta 4 Primary Antibody pour FACS, IHC (fro) - ABIN120281
Kennel, Godfrey, Chang, Lankford, Foote, Makkinje: The beta 4 subunit of the integrin family is displayed on a restricted subset of endothelium in mice. dans Journal of cell science 1992
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Human Monoclonal Integrin beta 4 Primary Antibody pour FACS - ABIN319861
Kennel, Epler, Lankford, Foote, Dickas, Canamucio, Cavalierie, Cosimelli, Venturo, Falcioni: Second generation monoclonal antibodies to the human integrin alpha 6 beta 4. dans Hybridoma 1990
Human Monoclonal Integrin beta 4 Primary Antibody pour FACS, ICC - ABIN4900094
Mierke, Frey, Fellner, Herrmann, Fabry: Integrin α5β1 facilitates cancer cell invasion through enhanced contractile forces. dans Journal of cell science 2011
Human Monoclonal Integrin beta 4 Primary Antibody pour FACS, IHC - ABIN1724805
Liu, Qin, Liu, Xiang: Downregulation of integrin β4 decreases the ability of airway epithelial cells to present antigens. dans PLoS ONE 2012
Mouse (Murine) Monoclonal Integrin beta 4 Primary Antibody pour FACS, IHC (fro) - ABIN260163
Lämmermann, Bader, Monkley, Worbs, Wedlich-Söldner, Hirsch, Keller, Förster, Critchley, Fässler, Sixt: Rapid leukocyte migration by integrin-independent flowing and squeezing. dans Nature 2008
Ferret Monoclonal Integrin beta 4 Primary Antibody pour ICC, FACS - ABIN260162
Tra, van Neck, Hovius, van Osch, Perez-Amodio: Characterization of a three-dimensional mucosal equivalent: similarities and differences with native oral mucosa. dans Cells, tissues, organs 2012
Expression of the beta 4 subunit of the alpha 6 beta 4 integrin induces monocytic differentiation of 32D/v-Abl (Montrer ABL1 Anticorps) transformed cells. alpha 6 beta 4 integrin promotes growth arrest and differentiation by modulating Abl (Montrer ABL1 Anticorps) kinases and p73 (Montrer ARHGAP24 Anticorps) protein pathway(s).
Integrin beta4 contributes to mammary gland development by sustaining PTHrP (Montrer PTHLH Anticorps) expression and enabling PTHrP (Montrer PTHLH Anticorps) signaling.
keratins have a role in controlling beta4-integrin endocytosis involving a plectin (Montrer PLEC Anticorps)-Erk1/2 (Montrer MAPK1/3 Anticorps)-dependent mechanism relevant for epidermal differentiation and pathogenesis
Up-regulation of integrin beta4 and TRPV1 (Montrer TRPV1 Anticorps) in migrating keratinocytes.
Ectopic induction of Nur77 (Montrer NR4A1 Anticorps) in endothelial cells is sufficient to improve skin wound healing. Furthermore, TR3/Nur77 (Montrer NR4A1 Anticorps) regulates the expression of integrin beta4 by targeting its promoter activity.
Col17a1 (Montrer COL17A1 Anticorps)/ keratinocytes exhibited increased spreading on laminin 332 and accelerated, but less directed cell motility. These effects were accompanied by increased expression of the integrin subunits beta4 and beta1.
Both annexin A7 (Montrer ANXA7 Anticorps) and integrin beta4 were essential for small molecule, 6-amino-2, 3-dihydro-3-hydroxymethyl-1, 4-benzoxazine-induced autophagy.
Findings indicate a function for Id2 in regulating Snai1 (Montrer SNAI1 Anticorps)-mediated repression of integrin beta4.
Targeted deletion of the signaling domain of beta4 inhibited prostate tumor growth and progression in response to loss of p53 (Montrer TP53 Anticorps) and Rb function in a model of prostate cancer (PB-TAg mice).
Deficiency of integrin alpha(6 (Montrer ITGA6 Anticorps))beta(4) is modestly but significantly suppressed reporter-gene transduction by papillomaviruses in conditional integrin beta(4) knockout mice.
data indicate that the beta4 integrin/FAK (Montrer PTK2 Anticorps) complex and subsequent FAK (Montrer PTK2 Anticorps) activation are essential regulators during the tumorigenicity of colon cancer
This work investigates alpha6beta4 integrin genetic variations (A380T and R1281W) and breast cancer risk in an Argentinian population. No subjects carrying the R1281W mutation in the ITGB4 gene were found and this absence could reflect its high deleterious impact on proteins, so it would be eliminated from the population by natural selection.
analysis of deletions in ITGB4 gene causing epidermolysis bullosa with pyloric atresia [case series]
ITGB4 is overexpressed in hepatocellular carcinoma tissues and promotes metastases of HCC (Montrer FAM126A Anticorps) by conferring anchorage independence through EGFR (Montrer EGFR Anticorps)-dependent FAK (Montrer PTK2 Anticorps)-AKT (Montrer AKT1 Anticorps) activation.
High vimentin and low beta4 integrin protein levels are associated with poor survival in oral squamous carcinoma patients.
Endothelial cell overexpression of mutant ITGB4 with specific tyrosines mutated to phenylalanine (Y1440, Y1526 Y1640, or Y1422) resulted in significantly attenuated CS-induced cytokine expression.
This study describes a pro-metastatic EGFR (Montrer EGFR Anticorps)/Src (Montrer SRC Anticorps)-dependent beta4 integrin/FAK (Montrer PTK2 Anticorps) complex that is involved in breast cancer malignancy and is a novel therapeutic target for triple-negative breast cancer.
These data suggest that the p53 (Montrer TP53 Anticorps)(R248) mutant endows ovarian cancer cells with increased adhesiveness and that integrin beta4 and Akt (Montrer AKT1 Anticorps) signalling are associated with the mutation-enhanced ovarian cancer-mesothelial cell adhesion.
Changes in beta-integrins gene expression in human prostate cancer cells following ITGB4 knockdown.
PKD2 (Montrer PKD2 Anticorps) and RSK1 (Montrer RPS6KA1 Anticorps) regulate integrin beta4 phosphorylation at threonine 1736 to stabilize keratinocyte cell adhesion and its hemidesmosomes.
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
integrin beta 4
, integrin beta-4
, CD104 antigen
, integrin beta-4 subunit