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The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. De plus, nous expédions IL27 Anticorps (194) et IL27 Protéines (23) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 51 products:
Human IL27 Kit ELISA pour Sandwich ELISA - ABIN414441
Li, Zhang, Ge, Zhou, Qi, Ma, Xue, Zhou, Yang: Elevated interleukin-27 enhances the polarization of Th1/Tc1 cells and the production of proinflammatory cytokines in primary immune thrombocytopenia. dans Human immunology 2012
Rat (Rattus) IL27 Kit ELISA pour Sandwich ELISA - ABIN416127
Gao, Pang, Zhang, Li, Tu, Zhang, Niu, Xiong, Xiao, Zhao, Gao, Wang: Poria Attenuates Idiosyncratic Liver Injury Induced by Polygoni Multiflori Radix Praeparata. dans Frontiers in pharmacology 2016
Human IL27 Kit ELISA pour Sandwich ELISA - ABIN365220
Le Texier, Thebault, Carvalho-Gaspar, Vignard, Merieau, Usal, Cuturi, Wood, Chiffoleau: Immunoregulatory function of IL-27 and TGF-?1 in cardiac allograft transplantation. dans Transplantation 2012
IL-27 polymorphisms might play a protective role for the development of ulcerative colitis in the Mexican population
IL-27 stimulation activated STAT1 (Montrer STAT1 Kits ELISA) and STAT3 (Montrer STAT3 Kits ELISA) in HeLa and T98G cells, suggesting that IL-27 engages the STAT1 (Montrer STAT1 Kits ELISA)/3 pathway, which then leads to the upregulation of IL-6 (Montrer IL6 Kits ELISA), IP-10 (Montrer CXCL10 Kits ELISA), and MIG (Montrer CXCL9 Kits ELISA)
IL-27 and IL-37 limit the induction of particular T cell subsets along with cytokine responses in S. stercoralis infections, which suggest the importance of IL-27 and IL-37 in immune modulation in a chronic helminth infection.
IL-27 is a pivotal regulator in endometriotic immune tolerance by triggering Th17 cells to produce IL-10 (Montrer IL10 Kits ELISA).
HIV and Tat (Montrer TAT Kits ELISA) inhibit LPS (Montrer IRF6 Kits ELISA)-induced IL-27 production in human macrophages via distinct mechanisms: Tat (Montrer TAT Kits ELISA) through the inhibition of cIAP-1 (Montrer BIRC2 Kits ELISA)-TRAF-6 (Montrer TRAF6 Kits ELISA) and subsequent inhibition of PI3K (Montrer PIK3CA Kits ELISA) and p38 (Montrer CRK Kits ELISA) MAPKs, whereas HIV through the inhibition of p38 MAPK (Montrer MAPK14 Kits ELISA) activation.
IL27 (Montrer EBI3 Kits ELISA) recapitulates IFN-gamma (Montrer IFNG Kits ELISA) responses in hepatocellular carcinoma cells, but is inhibited by IL6 (Montrer IL6 Kits ELISA)-type cytokines.
These findings provide new evidence that IL-27 plays an important role in the proinflammatory capacity of monocytes and macrophages via enhancing IL-1beta (Montrer IL1B Kits ELISA) secretion levels triggered by dual LPS (Montrer IRF6 Kits ELISA)-ATP stimulation.
IL-27 enhanced the cytotoxicity and suppressed the proliferation of ovarian cancer cells
the sIL (Montrer PMEL Kits ELISA)-6R/p28 (Montrer PSMD10 Kits ELISA) fusion protein (FP) upregulated IFN-lambda1 expression by increasing the binding abilities of c-Fos and activating transcription factor 1 (Montrer AFT1 Kits ELISA) to the IFN-lambda1 promoter via the p38 MAPK (Montrer MAPK14 Kits ELISA) signaling pathway; results demonstrate the important role of sIL (Montrer PMEL Kits ELISA)-6R/p28 (Montrer PSMD10 Kits ELISA) FP in mediating virus-induced type III IFN production.
These results identify IL-27 and its specific receptor IL27RA (Montrer IL27RA Kits ELISA) as a critical immune axis for the antiviral immune response and as robust correlates of viral load and proviral reservoir size in mononuclear leukocytes in HIV infection.
IL-27-induced Sca-1 (Montrer Ly6a Kits ELISA)(+) T cells had increased expression of effector/memory-associated transcription factor T-bet, Eomes (Montrer EOMES Kits ELISA) and Blimp1 (Montrer PRDM1 Kits ELISA).
found that during respiratory virus infection the prototypic inflammatory cytokine IL-6 (Montrer IL6 Kits ELISA) is a critical anti-inflammatory regulator of viral induced immunopathology in the respiratory tract through its induction of IL-27
We demonstrate that IL-27-deficiency is linked to increased mucosal presence of ILC2 in a model of inflammatory lung disease. Moreover, IL-27-treatment inhibited ILC2 proliferation and cytokine production and significantly reduced their accumulation in vivo.
These data suggest a novel role of the sympathetic neuroendocrine system for the modulation of IL-27-dependent acute inflammation.
results identified a novel mechanism of action of IL-27 on Tregs in the context of cancers.
These findings provide new evidence that IL-27 plays an important role in the proinflammatory capacity of monocytes and macrophages via enhancing IL-1beta (Montrer IL1B Kits ELISA) secretion levels triggered by dual LPS (Montrer TLR4 Kits ELISA)-ATP stimulation.
findings show that PGE2 inhibits IL-27 production in macrophages and in splenic conventional dendritic cells; and identify a novel pathway consisting of signaling through EP2/EP4-->induction of cAMP-->downregulation of IFN regulatory factor 1 expression and binding to the p28 IFN-stimulated response element site
these data provide the first evidence that IL-27 signals directly to B (Montrer TDO2 Kits ELISA) cells promote GCs (Montrer UGCG Kits ELISA) and support the role of IL-27 in lupus.
this study shows that IL-27 plays an important role in immune response and pathogen clearance during infection with Candida parapsilosis
Inhibition of IL-27p28 also enhanced the suppressive capacity of adoptively transferred CD4 (Montrer CD4 Kits ELISA)(+) nTregs by increasing the stability of Foxp3 (Montrer FOXP3 Kits ELISA) expression.
The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).
The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
IL-27 p28 subunit
, IL-27 subunit alpha
, interleukin 30
, interleukin-27 subunit alpha
, interluekin 27
, interleukin 27
, interleukin 27 p28 subunit