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The protein encoded by ISCA2 is an A-type iron-sulfur cluster (ISC) protein found in mitochondria. De plus, nous expédions Iron-Sulfur Cluster Assembly 2 Homolog (S. Cerevisiae) Protéines (5) et beaucoup plus de produits pour cette protéine.
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Cow (Bovine) Polyclonal ISCA2 Primary Antibody pour WB - ABIN2785399
Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ... dans Genome research 2004
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We identified a homoallelic missense founder mutation in ISCA2 leading to mitochondrial depletion and reduced complex I activity as well as decreased ISCA2, ISCA1 (Montrer ISCA1 Anticorps) and IBA57 (Montrer IBA57 Anticorps) expression in fibroblasts.
The structural plasticity of the dimeric state of the [2Fe-2S] bound form of human GRX5 (Montrer GLRX5 Anticorps) is the crucial factor that allows an efficient cluster transfer to the partner proteins human ISCA1 (Montrer ISCA1 Anticorps) and ISCA2 by a specific protein-protein recognition mechanism.
ISCA1 (Montrer ISCA1 Anticorps), ISCA2, and IBA57 (Montrer IBA57 Anticorps) were depleted by RNA interference. Depleted cells contained massively swollen and enlarged mitochondria that were virtually devoid of cristae membranes, demonstrating the importance of these proteins for mitochondrial biogenesis.
Data suggest that miR (Montrer MLXIP Anticorps)-210 induced repression of ISCU1/2 may contribute to HIF-1alpha (Montrer HIF1A Anticorps)-triggered alterations in neuronal energy metabolism after nickel exposure.
The protein encoded by this gene is an A-type iron-sulfur cluster (ISC) protein found in mitochondria. The encoded protein appears to be involved in the maturation of mitochondrial iron-sulfur proteins. Two transcript variants encoding different isoforms have been found for this gene.
HESB-like domain-containing protein 1
, iron-sulfur cluster assembly 2 homolog, mitochondrial
, HESB like domain containing 1
, iron-sulfur cluster assembly 2 homolog