anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) Anticorps

The protein encoded by LIMS1 is an adaptor protein which contains five LIM domains, or double zinc fingers. De plus, nous expédions LIM and Senescent Cell Antigen-Like Domains 1 Protéines (5) et LIM and Senescent Cell Antigen-Like Domains 1 Kits (1) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
LIMS1 3987 P48059
LIMS1 499443  
LIMS1 110829 Q99JW4
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Top anti-LIM and Senescent Cell Antigen-Like Domains 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 55 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-LIMS1 Antibody Titration: 1.0 ug/ml Positive Control: U937 Whole Cell 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB <b>Host: </b>Rabbit<br><b>Target Name: </b>LIMS1<br><b>Antibody Dilution: </b>1.0ug/ml<br><b>Sample Tissue: </b>MCF7 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Poulet Souris Inconjugué IF, WB Western blot analysis of PINCH on K-562 lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of anti-PINCH antibody. 150 μg Connectez-vous pour afficher 6 to 8 Days
$283.13
Détails
Humain Souris Inconjugué ICC, FACS, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of Hela cells using PINCH mouse mAb (blue) and negative control (red) . 100 μL Connectez-vous pour afficher 2 to 3 Days
$430.10
Détails
Humain Lapin Inconjugué WB LIMS3/LIMS3L Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the LIMS3/LIMS3L antibody detected the LIMS3/LIMS3L protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Souris Inconjugué EIA, IF, WB 0.1 mL Connectez-vous pour afficher 6 to 8 Days
$423.50
Détails
Humain Lapin Inconjugué ICC, IHC, IP, WB 100 μg Connectez-vous pour afficher 13 to 16 Days
$384.00
Détails
Humain Souris Inconjugué ICC, FACS, IF, ELISA, WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Souris Lapin Inconjugué WB Western Blot: LIMS1 Antibody [NBP1-31220] - Analysis of LIMS1 Antibody on: A:293T B:Raji 10% SDS PAGE diluted at 1:2000 100 μL Connectez-vous pour afficher 7 to 9 Days
$447.56
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Immunohistochemistry-Paraffin: PINCH1/LIMS1 Antibody [NBP2-19354] - Analysis of paraffin-embedded BT474 xenograft, using antibody at 1:100 dilution. Western Blot: PINCH1/LIMS1 Antibody [NBP2-19354] - A: Hela. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$447.56
Détails

LIMS1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-LIM and Senescent Cell Antigen-Like Domains 1 Anticorps mieux référencés

  1. Chicken Monoclonal LIMS1 Primary Antibody pour IF, WB - ABIN968920 : Campana, Myers, Rearden: Identification of PINCH in Schwann cells and DRG neurons: shuttling and signaling after nerve injury. dans Glia 2003 (PubMed)
    Show all 3 Pubmed References

  2. Chicken Monoclonal LIMS1 Primary Antibody pour IF, WB - ABIN968921 : Tu, Li, Goicoechea, Wu: The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells. dans Molecular and cellular biology 1999 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal LIMS1 Primary Antibody pour FACS, IF - ABIN966832 : Yang, Wang, Hawkins, Chen, Vaynberg, Mao, Tu, Zuo, Wang, Wang, Wu, Tjandra, Qin: Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase. dans The Journal of biological chemistry 2009 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal LIMS1 Primary Antibody pour ICC, FACS - ABIN969354 : Chiswell, Zhang, Murphy, Boggon, Calderwood: The structural basis of integrin-linked kinase-PINCH interactions. dans Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre LIM and Senescent Cell Antigen-Like Domains 1 partenaires d’interaction

Human LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) interaction partners

  1. Mammalian cells have two functional PINCH proteins, PINCH1 and PINCH2 (Montrer LIMS2 Anticorps). PINCH not only binds to Nck2 (Montrer NCK2 Anticorps) and engages in the signaling of growth factor receptors, but also forms a ternary complex with ILK (Montrer ILK Anticorps) and parvin (Montrer PARVA Anticorps) (IPP (Montrer IPP Anticorps) complex).

  2. our data suggest an essential role of PINCH1, ILK (Montrer ILK Anticorps) and ILKAP (Montrer ILKAP Anticorps) for the radioresistance of p53 (Montrer TP53 Anticorps)-wildtype glioblastoma multiforme cells

  3. Data suggest that PINCH1 and Nck2 (Montrer NCK2 Anticorps) critically participate in the regulation of cellular radiosensitivity and EGFR (Montrer EGFR Anticorps) function and downstream signaling in a cellular model of human squamous cell carcinoma.

  4. Downregulation of PINCH1 is associated with metastatic breast cancer.

  5. changes in CSF (Montrer CSF2 Anticorps) levels of PINCH appear to correlate with changes in blood CD4 (Montrer CD4 Anticorps) count and with changes in CSF (Montrer CSF2 Anticorps) hyperphosphorylated Tau levels

  6. two novel genes, galectin 9 (Montrer LGALS9 Anticorps) and PINCH, were expressed at much higher levels in cancerous lesions than in normal tissues in all the patients with clear-cell carcinoma who were examined

  7. PINCH predicts survival in rectal cancer patients with RT, but not in patients without RT. The expression of PINCH may be regulated by radiation and by environmental factors surrounding the cells.

  8. PINCH is increased and binds to hp-Tau. These studies address a new mechanism by which AD and HIV may intersect and identify PINCH as a contributing factor to the accumulation of hyperphosphorylated Tau.

  9. Pinch-1 mRNA and protein were significantly up-regulated in acute lymphoblastic leukemia and acute myeloid leukemia (Montrer BCL11A Anticorps) bone marrow stromal cells compared to normal bone marrow stromal cells (p<0.01).

  10. PINCH protein might play an important role in the tumourigenesis and metastasis of gastric adenocarcinoma.

Mouse (Murine) LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) interaction partners

  1. findings suggest that PINCH-1 regulates integrin-mediated adhesion of keratinocytes through the interactions with ILK (Montrer ILK Anticorps) as well as EPLIN (Montrer LIMA1 Anticorps).

  2. Rsu-1 (Montrer RSU1 Anticorps) expression is dramatically decreased in PINCH double knockout mouse livers.

  3. PINCH is increased and binds to hp-Tau. These studies address a new mechanism by which AD and HIV may intersect and identify PINCH as a contributing factor to the accumulation of hyperphosphorylated Tau.

  4. PINCH-1 inhibits JNK (Montrer MAPK8 Anticorps)-mediated apoptosis by stabilising the PINCH-1 binding protein RSU-1 (Montrer RSU1 Anticorps) and promotes Bcl-2 (Montrer BCL2 Anticorps)-dependent pro-survival signalling downstream of integrins.

  5. Data suggest that the adapter protein (Montrer GRB10 Anticorps) PINCH1 critically participates in the regulation of the cellular radiosensitivity of normal and malignant cells similarly under adhesion and suspension conditions.

  6. PINCH1 plays an essential role in early murine embryonic development but is dispensable in ventricular cardiomyocytes.

  7. These results provide important evidence for a crucial role of the PINCH-1-ILK (Montrer ILK Anticorps)-alpha-parvin (Montrer PARVA Anticorps) complex in the control of podocyte adhesion, morphology, and survival.

  8. LIM (Montrer PDLIM5 Anticorps) 5 domain of PINCH1 interacts with Rsu-1 (Montrer RSU1 Anticorps) in mammalian cells and functions, in part, by altering cell adhesion.

  9. The PINCH1 is composed of 5 LIM domains, binds ILK and locates to integrin-mediated adhesion sites, and PINCH1 is for integrin function, actin organization, cell-cell adhesion and endodermal cell survival during the implanting of mouse embryos.

  10. PICH1, Ilk (Montrer ILK Anticorps) and alpha-parvin (Montrer PARVA Anticorps) form a complex to costameres in neonatal mouse ventricular myocytes. This complex is stimulated by fibronectins and phenylephrine, and by both by drug synergism, to regulate cardiac myocyte hypertrophy.

LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) profil antigène

Profil protéine

The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with LIMS1

  • LIM zinc finger domain containing 1 (LIMS1) anticorps
  • LIM zinc finger domain containing 1 (Lims1) anticorps
  • LIM and senescent cell antigen-like domains 1 (Lims1) anticorps
  • 2310016J22Rik anticorps
  • 4921524A02Rik anticorps
  • AI507642 anticorps
  • AU021743 anticorps
  • AW551584 anticorps
  • C430041B13Rik anticorps
  • Lims1l anticorps
  • LIMS3 anticorps
  • LIMS3L anticorps
  • PINCH anticorps
  • PINCH-1 anticorps
  • Pinch1 anticorps
  • RGD1560732 anticorps

Protein level used designations for LIMS1

LIM and senescent cell antigen-like-containing domain protein 1 , particularly interesting new Cys-His protein 1 , renal carcinoma antigen NY-REN-48

GENE ID SPECIES
3987 Homo sapiens
499443 Rattus norvegicus
414880 Gallus gallus
474540 Canis lupus familiaris
100511559 Sus scrofa
540281 Bos taurus
110829 Mus musculus
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