LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) Kits ELISA

The protein encoded by LIMS1 is an adaptor protein which contains five LIM domains, or double zinc fingers. De plus, nous expédions LIM and Senescent Cell Antigen-Like Domains 1 Anticorps (55) et LIM and Senescent Cell Antigen-Like Domains 1 Protéines (5) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
LIMS1 3987 P48059
Anti-Rat LIMS1 LIMS1 499443  
Anti-Souris LIMS1 LIMS1 110829 Q99JW4
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 0.056 ng/mL 0.15-10 ng/mL 96 Tests Connectez-vous pour afficher 11 to 15 Days
651,85 €
Détails

Plus Kits ELISA pour LIM and Senescent Cell Antigen-Like Domains 1 partenaires d'interaction

Human LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) interaction partners

  1. Mammalian cells have two functional PINCH proteins, PINCH1 and PINCH2 (Montrer LIMS2 Kits ELISA). PINCH not only binds to Nck2 and engages in the signaling of growth factor receptors, but also forms a ternary complex with ILK (Montrer ILK Kits ELISA) and parvin (Montrer PARVA Kits ELISA) (IPP (Montrer IPP Kits ELISA) complex).

  2. our data suggest an essential role of PINCH1, ILK (Montrer ILK Kits ELISA) and ILKAP (Montrer ILKAP Kits ELISA) for the radioresistance of p53 (Montrer TP53 Kits ELISA)-wildtype glioblastoma multiforme cells

  3. Data suggest that PINCH1 and Nck2 critically participate in the regulation of cellular radiosensitivity and EGFR (Montrer EGFR Kits ELISA) function and downstream signaling in a cellular model of human squamous cell carcinoma.

  4. Downregulation of PINCH1 is associated with metastatic breast cancer.

  5. changes in CSF (Montrer CSF2 Kits ELISA) levels of PINCH appear to correlate with changes in blood CD4 (Montrer CD4 Kits ELISA) count and with changes in CSF (Montrer CSF2 Kits ELISA) hyperphosphorylated Tau levels

  6. two novel genes, galectin 9 (Montrer LGALS9 Kits ELISA) and PINCH, were expressed at much higher levels in cancerous lesions than in normal tissues in all the patients with clear-cell carcinoma who were examined

  7. PINCH predicts survival in rectal cancer patients with RT, but not in patients without RT. The expression of PINCH may be regulated by radiation and by environmental factors surrounding the cells.

  8. PINCH is increased and binds to hp-Tau. These studies address a new mechanism by which AD and HIV may intersect and identify PINCH as a contributing factor to the accumulation of hyperphosphorylated Tau.

  9. Pinch-1 mRNA and protein were significantly up-regulated in acute lymphoblastic leukemia and acute myeloid leukemia (Montrer BCL11A Kits ELISA) bone marrow stromal cells compared to normal bone marrow stromal cells (p<0.01).

  10. PINCH protein might play an important role in the tumourigenesis and metastasis of gastric adenocarcinoma.

Mouse (Murine) LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) interaction partners

  1. findings suggest that PINCH-1 regulates integrin-mediated adhesion of keratinocytes through the interactions with ILK (Montrer ILK Kits ELISA) as well as EPLIN (Montrer LIMA1 Kits ELISA).

  2. Rsu-1 (Montrer RSU1 Kits ELISA) expression is dramatically decreased in PINCH double knockout mouse livers.

  3. PINCH is increased and binds to hp-Tau. These studies address a new mechanism by which AD and HIV may intersect and identify PINCH as a contributing factor to the accumulation of hyperphosphorylated Tau.

  4. PINCH-1 inhibits JNK (Montrer MAPK8 Kits ELISA)-mediated apoptosis by stabilising the PINCH-1 binding protein RSU-1 (Montrer RSU1 Kits ELISA) and promotes Bcl-2 (Montrer BCL2 Kits ELISA)-dependent pro-survival signalling downstream of integrins.

  5. Data suggest that the adapter protein (Montrer GRB10 Kits ELISA) PINCH1 critically participates in the regulation of the cellular radiosensitivity of normal and malignant cells similarly under adhesion and suspension conditions.

  6. PINCH1 plays an essential role in early murine embryonic development but is dispensable in ventricular cardiomyocytes.

  7. These results provide important evidence for a crucial role of the PINCH-1-ILK (Montrer ILK Kits ELISA)-alpha-parvin (Montrer PARVA Kits ELISA) complex in the control of podocyte adhesion, morphology, and survival.

  8. LIM (Montrer PDLIM5 Kits ELISA) 5 domain of PINCH1 interacts with Rsu-1 (Montrer RSU1 Kits ELISA) in mammalian cells and functions, in part, by altering cell adhesion.

  9. The PINCH1 is composed of 5 LIM domains, binds ILK and locates to integrin-mediated adhesion sites, and PINCH1 is for integrin function, actin organization, cell-cell adhesion and endodermal cell survival during the implanting of mouse embryos.

  10. PICH1, Ilk (Montrer ILK Kits ELISA) and alpha-parvin (Montrer PARVA Kits ELISA) form a complex to costameres in neonatal mouse ventricular myocytes. This complex is stimulated by fibronectins and phenylephrine, and by both by drug synergism, to regulate cardiac myocyte hypertrophy.

LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) profil antigène

Antigen Summary

The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with LIMS1

  • LIM and senescent cell antigen-like domains 1 (LIMS1) anticorps
  • LIM and senescent cell antigen-like domains 1 (Lims1) anticorps
  • 2310016J22Rik anticorps
  • 4921524A02Rik anticorps
  • AI507642 anticorps
  • AU021743 anticorps
  • AW551584 anticorps
  • C430041B13Rik anticorps
  • Lims1l anticorps
  • LIMS3 anticorps
  • LIMS3L anticorps
  • PINCH anticorps
  • PINCH-1 anticorps
  • Pinch1 anticorps
  • RGD1560732 anticorps

Protein level used designations for LIMS1

LIM and senescent cell antigen-like-containing domain protein 1 , particularly interesting new Cys-His protein 1 , renal carcinoma antigen NY-REN-48

GENE ID SPECIES
3987 Homo sapiens
499443 Rattus norvegicus
414880 Gallus gallus
474540 Canis lupus familiaris
100511559 Sus scrofa
540281 Bos taurus
110829 Mus musculus
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