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LRP8 encodes a member of the low density lipoprotein receptor (LDLR) family. De plus, nous expédions LRP8 Kits (14) et LRP8 Protéines (10) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 94 products:
Chicken Polyclonal LRP8 Primary Antibody pour ICC, IF - ABIN151639
Wang, Moerman-Herzog, Slaton, Barger: Presenilin 1 mutations influence processing and trafficking of the ApoE receptor apoER2. dans Neurobiology of aging 2016
Human Monoclonal LRP8 Primary Antibody pour ELISA, WB - ABIN563474
Liu, Wu, Baysarowich, Kavana, Addona, Bierilo, Mudgett, Pavlovic, Sitlani, Renger, Hubbard, Fisher, Zerbinatti: PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain. dans Journal of lipid research 2010
LRP8 is a risk gene for psychosis.
These results reveal an association between ApoER2 isoform expression and Alzheimer's disease.
The presence of reelin (Montrer RELN Anticorps) was elevated in junctional areas as in dysplastic nevi. VLDLR (Montrer VLDLR Anticorps) presented positive values in 16 cases (16/ 32) and ApoER2 was weak positive in 7 cases.
ApoER2 contributes cooperatively with endothelial cell protein C receptor (Montrer PROCR Anticorps) and protease activated receptor 1 (Montrer F2R Anticorps) to APC (Montrer APC Anticorps)-initiated endothelial antiapoptotic and barrier protective signaling.
two SNPs (rs3737984 and rs2297660) in ApoER2 gene had significant association with dyslipidemia in Thai ethnic
A novel TACGC risk haplotype in the LRP8 gene that is present in patients with CAD (Montrer CAD Anticorps) and MI but not in normal controls.
results of this study demonstrated the presence of reelin (Montrer RELN Anticorps), its receptors VLDLR (Montrer VLDLR Anticorps) and ApoER2 as well as Dab1 (Montrer DAB1 Anticorps) in the ENS and might indicate a novel role of the reelin (Montrer RELN Anticorps) system in regulating neuronal plasticity and pre-synaptic functions in the ENS.
Data suggest that PS1 (Montrer PSEN1 Anticorps)/gamma-secretase-dependent processing of the reelin (Montrer RELN Anticorps) receptor ApoER2 inhibits reelin (Montrer RELN Anticorps) expression and may regulate its signaling.
ectopic expression of HIC1 (Montrer HIC1 Anticorps) in U2OS and MDA-MB-231 cell lines decreases expression of the ApoER2 and VLDLR (Montrer VLDLR Anticorps) genes, encoding two canonical tyrosine kinase (Montrer TXK Anticorps) receptors for Reelin (Montrer RELN Anticorps).
By incorporating the information from bioinformatics and RNA expression analyses, we identified at least two of the most promising risk genes for alcohol dependence: APOER2 and UBAP2 (Montrer UBAP2 Anticorps)
A1-A1, which is a soluble analog of ApoER2 that binds pathological beta2GPI/anti-beta2GPI complexes, has a positive impact on hemodynamics in lupus-prone mice with spontaneous anti-beta2GPI antibodies and hypertension
findings indicate that impaired processing or localization of apoER2 may contribute to the pathogenic effects of familial Alzheimer's disease mutations in PS1 (Montrer PSEN1 Anticorps)
reveals a novel function for Reelin (Montrer RELN Anticorps)/ApoER2 in peripheral nervous system, inducing cell migration of Schwann cells, a process relevant for peripheral nervous system development and regeneration
total levels of ApoER2 and surface levels of ApoER2 are increased by active Fyn (Montrer FYN Anticorps)
This study demonstrated that ApoER2 is expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex.
This study demonistrated that LRP8-Reelin (Montrer RELN Anticorps)-Regulated Neuronal Enhancer Signature Underlying Learning and Memory Formation in mice.
Apoer2 lacking exon 16, the O-linked sugar domain, altered the proteolytic processing and abundance of Apoer2 in cells and synapse number and function in mice, hippocampal spine density, LTP (Montrer SCP2 Anticorps), and cued fear learning.
genetic variants of apoE (Montrer APOE Anticorps) and ApoER2 impact cardiovascular health by differentially modulating endothelial function.
Study shows that the levels of hippocampal ApoE (Montrer APOE Anticorps) receptors Lrp1 (Montrer LRP1 Anticorps) and Apoer2 in vivo are affected isoform specifically by ApoE4 and that the type of receptor affected is context dependent
Tandem Sepp1 (Montrer SEPP1 Anticorps)-apoER2 interactions supply selenium for maintenance of brain neurons both at the blood-brain barrier and within the brain. Sepp1 (Montrer SEPP1 Anticorps) inside the blood-brain barrier is taken up by neurons via apoER2, concentrating brain selenium in them.
genetic variants of apoE (Montrer APOE Anticorps) and ApoER2 impact cardiovascular health by differentially modulating endothelial function.[ApoER2]
the differential expression patterns of LRP8 mRNA during final follicular growth and ovulation
This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
, low density lipoprotein receptor-related protein 8
, low-density lipoprotein receptor-related protein 8-like
, ApoE receptor 2
, low-density lipoprotein receptor-related protein 8
, apolipoprotein E receptor 2
, low density lipoprotein receptor relative, 8 ligand binding repeats, brain