anti-MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1) Anticorps

MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. De plus, nous expédions MAD2L1 Protéines (8) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
MAD2L1 56150 Q9Z1B5
MAD2L1 4085 Q13257
MAD2L1 297176  
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Top anti-MAD2L1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 122 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-MAD2L1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Souris Inconjugué IP, WB 0.1 mg Connectez-vous pour afficher 8 to 10 Days
440,00 €
Détails
Humain Souris Inconjugué IHC (p), IP, WB IImmunohistochemistry of normal testis (formalin fixed) after antigen retreival, stained with Anti-Mad2L1 (clone 17D10)). Primary spermatocytes show staining of both the cytoplasm and nucleus. Picture kindly supplied by M.d.Espen Burum-Auensen from Rikshospitalet, Norway 50 μL Connectez-vous pour afficher 3 to 4 Days
385,00 €
Détails
Humain Souris Inconjugué WB MAD2L1 monoclonal antibody (M01), clone 2E2-1D6 Western Blot analysis of MAD2L1 expression in HeLa. Detection limit for recombinant GST tagged MAD2L1 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), IP, IHC, WB Immunohistochemistry-Paraffin: MAD2L1 Antibody [NBP1-31311] - Paraffin-embedded DLD-1 xenograft, using antibody at 1:500 dilution. Western Blot: MAD2L1 Antibody [NBP1-31311] - A:Hep G2 B:MOLT4 C:Raji 12% SDS PAGE NBP1-31311 diluted at 1:1000 100 μL Connectez-vous pour afficher 3 to 5 Days
426,25 €
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), IP Detection of human MAD2 by Western Blot and Immunoprecipitation. Samples: NETN whole cell lysate (50 ug for WB, 600 ug for IP) from HeLa cells. Antibodies: ABIN151995 used at 1 ug/ml for WB (A) and at 0.7 ug/mg lysate for IP (B). MAD2 was also immunoprecipitated using rabbit anti-MAD2 antibody ABIN151996 at 0.7 ug/mg lysate. Immunoprecipitated MAD2 was blotted using ABIN151996 at 0.2 ug/ml. Detection: Chemiluminescence with an exposure time of 1 minute (A and B). Immunohistochemistry-Paraffin: MAD2L1 Antibody [ABIN151995] - Section of human lung carcinoma. 100 μL Connectez-vous pour afficher 3 to 5 Days
463,75 €
Détails
Humain Lapin Inconjugué WB Anti- Mad2L1 Picoband antibody, Western blotting All lanes: Anti Mad2L1  at 0.5ug/ml Lane 1: 293T Whole Cell Lysate at 40ug Lane 2: COLO320 Whole Cell Lysate at 40ug Predicted bind size: 23KD Observed bind size: 23KD 100 μg Connectez-vous pour afficher 8 to 11 Days
340,48 €
Détails
Humain Lapin Inconjugué EIA, WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
391,60 €
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 3 to 4 Days
349,82 €
Détails
Humain Lapin Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails

MAD2L1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-MAD2L1 Anticorps mieux référencés

  1. Human Polyclonal MAD2L1 Primary Antibody pour ICC, IF - ABIN151995 : Wu, Glickstein, Liu, Fujita, Li, Yang, Duvoisin, Wan: The anaphase-promoting complex coordinates initiation of lens differentiation. dans Molecular biology of the cell 2007 (PubMed)
    Show all 12 references for 151995

  2. Human Monoclonal MAD2L1 Primary Antibody pour WB - ABIN395553 : Hewitt, Tighe, Santaguida, White, Jones, Musacchio, Green, Taylor: Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex. dans The Journal of cell biology 2010 (PubMed)
    Show all 5 references for 395553

  3. Human Monoclonal MAD2L1 Primary Antibody pour IHC (p), IP - ABIN108556 : Burum-Auensen, Deangelis, Schjølberg, Røislien, Andersen, Clausen: Spindle proteins Aurora A and BUB1B, but not Mad2, are aberrantly expressed in dysplastic mucosa of patients with longstanding ulcerative colitis. dans Journal of clinical pathology 2007 (PubMed)
    Show all 4 references for 108556

  4. Human Monoclonal MAD2L1 Primary Antibody pour IP, WB - ABIN567786 : Wei, Chou, Ou, Yeh, Tyan, Sun, Shen, Shieh: TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68. dans The Journal of biological chemistry 2005 (PubMed)
    Show all 2 references for 567786

  5. Human Polyclonal MAD2L1 Primary Antibody pour ELISA, WB - ABIN1452186 : Li, Benezra: Identification of a human mitotic checkpoint gene: hsMAD2. dans Science (New York, N.Y.) 1996 (PubMed)

  6. Human Polyclonal MAD2L1 Primary Antibody pour ICC, IF - ABIN441319 : Itoh, Sugino, Ikeda, Mizuguchi, Kanno, Amin, Iemura, Yasui, Hirota, Tanaka: Nucleoporin Nup188 is required for chromosome alignment in mitosis. dans Cancer science 2013 (PubMed)

  7. Cow (Bovine) Polyclonal MAD2L1 Primary Antibody pour WB - ABIN2792179 : Hisaoka, Matsuyama, Hashimoto: Aberrant MAD2 expression in soft-tissue sarcoma. dans Pathology international 2008 (PubMed)

Plus d’anticorps contre MAD2L1 partenaires d’interaction

Mouse (Murine) MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1) interaction partners

  1. p31comet-induced cell death is mediated by interactions with Mad2 (Montrer MXI1 Anticorps)

  2. study shows that Mad2 (Montrer MXI1 Anticorps) is a novel substrate for CCP6 (Montrer AGBL4 Anticorps) in megakaryocytes; Mad2 (Montrer MXI1 Anticorps) polyglutamylation plays a crucial role in the regulation of megakaryopoiesis

  3. Exacerbating chromosome missegregation in CENP-E (Montrer CENPE Anticorps)+/- mice by reducing levels of another mitotic checkpoint component (Montrer BUB3 Anticorps), Mad2 (Montrer MXI1 Anticorps), results in elevated cell death and decreased tumor formation compared with reduction of either protein alone.

  4. Mad2 (Montrer MXI1 Anticorps) is also repressed by p53 (Montrer TP53 Anticorps) and its upregulation is required for chromosome instability in a p53 (Montrer TP53 Anticorps) mutant tumor model

  5. Data show that Mad2 (Montrer MXI1 Anticorps) haploinsufficiency is protective in the presence of a cycle-specific DNA synthesis agent in vivo, and Ape1/Ref-1 (Montrer APEX1 Anticorps) inhibitor in vitro.

  6. Pcid2 (Montrer PCID2 Anticorps) is essential for B cell survival through the regulation of MAD2 (Montrer MXI1 Anticorps) expression during B cell differentiation

  7. tumours that experience transient Mad2 (Montrer MXI1 Anticorps) overexpression and consequent chromosome instability recur at markedly elevated rates

  8. a functional Mad2 (Montrer MXI1 Anticorps)-dependent spindle checkpoint exists during the first meiotic division in mammalian oocytes

  9. Data show that the loss of Trrap (Montrer TRRAP Anticorps) leads to chromosome missegregation, mitotic exit failure and compromised mitotic checkpoints, which are caused by defective Trrap (Montrer TRRAP Anticorps)-mediated transcription of the mitotic checkpoint (Montrer BUB3 Anticorps) proteins Mad1 (Montrer MXD1 Anticorps) and Mad2 (Montrer MXI1 Anticorps).

  10. that Brca1 (Montrer BRCA1 Anticorps)(Delta11/Delta11) cells displayed decreased expression of a number of genes that are involved in the spindle checkpoint, including Mad2 (Montrer MXI1 Anticorps)

Human MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1) interaction partners

  1. Thes authors show that p31 (Montrer ATP6V1E1 Anticorps)(comet) binding to the TRIP13 (Montrer TRIP13 Anticorps) N-terminal domain positions the disordered MAD2 N-terminus for engagement by the TRIP13 (Montrer TRIP13 Anticorps) "pore loops", which then unfold MAD2 in the presence of ATP.

  2. catalytic activation of the spindle assembly checkpoint depends on regulated protein-protein interactions that accelerate the spontaneous but rate-limiting conversion of MAD2 required for mitotic checkpoint (Montrer BUB3 Anticorps) complex assembly

  3. in addition to its role in checkpoint signaling, MAD2 ensures chromosome stability through the regulation of AURORA B (Montrer AURKB Anticorps).

  4. Aberrant Mad2 expression was associated with cell proliferation and genetic instability, which may contribute to the carcinogenesis of PGI (Montrer BGN Anticorps)-DLBCL. Mad2 overexpression indicated a poor DFS (Montrer FST Anticorps).

  5. interactions between Mad2 and H3K4 regulate resolution of the spindle assembly checkpoint by limiting closed Mad2 availability for Cdc20 (Montrer CDC20 Anticorps) inhibition.

  6. we showed that BubR1 (Montrer BUB1B Anticorps) and Mad2 are overexpressed in oral squamous cell carcinoma cell lines and linked such overexpression to attenuated spindle assembly checkpoint activity.

  7. Studied the folding/unfolding process of the open and closed conformers of human Mad2.

  8. MAD1L1 (Montrer MAD1L1 Anticorps) Arg558His and MAD2L1 Leu84Met interaction with smoking increase the risk of colorectal cancer

  9. p31comet-induced cell death is mediated by interactions with Mad2

  10. MAD2L1 and BUB1 (Montrer BUB1 Anticorps) may play important roles in breast cancer progression, and measuring the expression of these genes may assist the prediction of breast cancer prognosis.

MAD2L1 profil antigène

Profil protéine

MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14.

Gene names and symbols associated with MAD2L1

  • MAD2 mitotic arrest deficient-like 1 (yeast) (MAD2L1) anticorps
  • MAD2 mitotic arrest deficient-like 1 (yeast) (mad2l1) anticorps
  • MAD2 mitotic arrest deficient-like 1 (mad2l1) anticorps
  • MAD2 mitotic arrest deficient-like 1 (MAD2L1) anticorps
  • MAD2 mitotic arrest deficient-like 1 (yeast) (LOC100218172) anticorps
  • MAD2 mitotic arrest deficient-like 1 (Mad2l1) anticorps
  • MAD2 mitotic arrest deficient-like 1 (yeast) (Mad2l1) anticorps
  • AA673185 anticorps
  • cb408 anticorps
  • HSMAD2 anticorps
  • MAD2 anticorps
  • MAD2L1 anticorps
  • XMad2 anticorps
  • zgc:112133 anticorps

Protein level used designations for MAD2L1

MAD2-like 1 , mitotic spindle assembly checkpoint protein MAD2A , spindle assembly checkpoint protein Mad2 , MAD2 mitotic arrest deficient-like 1 (yeast) , MAD2 mitotic arrest deficient-like 1 , MAD2 (mitotic arrest deficient, homolog)-like 1 , MAD2-like protein 1 , mitotic arrest deficient 2-like protein 1 , MAD2 (mitotic arrest deficient, yeast, homolog)-like 1 , mitotic arrest deficient, yeast, homolog-like 1

GENE ID SPECIES
461661 Pan troglodytes
550434 Danio rerio
708574 Macaca mulatta
787996 Bos taurus
100125170 Xenopus (Silurana) tropicalis
100137358 Papio anubis
100218172 Taeniopygia guttata
56150 Mus musculus
380433 Xenopus laevis
4085 Homo sapiens
422675 Gallus gallus
476070 Canis lupus familiaris
337870 Bos taurus
297176 Rattus norvegicus
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