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transports lactic acid and other monocarboxylic acids. De plus, nous expédions Malignant T Cell Amplified Sequence 1 Protéines (13) et Malignant T Cell Amplified Sequence 1 Kits (9) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal MCTS1 Primary Antibody pour EIA, WB - ABIN453186
Kasiappan, Shih, Chu, Chen, Liu, Huang, Choy, Shu, Din, Chu, Hsu: Loss of p53 and MCT-1 overexpression synergistically promote chromosome instability and tumorigenicity. dans Molecular cancer research : MCR 2009
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Cow (Bovine) Polyclonal MCTS1 Primary Antibody pour WB - ABIN2779047
Shi, Levenson, Gartenhaus: Identification and characterization of a novel enhancer for the human MCT-1 oncogene promoter. dans Journal of cellular biochemistry 2003
Human Polyclonal MCTS1 Primary Antibody pour WB - ABIN4891880
Haas, Ngo, Li, Schleich, Qu, Vanyai, Cullen, Cardona-Alberich, Gladwyn-Ng, Pagnamenta, Taylor, Stewart, Kini, Duncan, Teleman, Keays, Heng: De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation. dans Cell reports 2016
Human Polyclonal MCTS1 Primary Antibody pour WB - ABIN152954
Kumar, Kant, Singh et al.: Antitumor and chemosensitizing action of dichloroacetate implicates modulation of tumor microenvironment: a role of reorganized glucose metabolism, cell survival regulation and macrophage ... dans Toxicology and applied pharmacology 2013
It was concluded that both MCT1 and CAII (Montrer CA2 Anticorps) are involved in the homeostatic control of pH in skeletal muscle, both at rest and at the onset of exercise. The improved muscle function and resistance to fatigue in MCT1(+/-) mice remain unexplained.
MCT1 inhibition impairs proliferation of glycolytic breast cancer cells co-expressing MCT1 and MCT4 (Montrer SLC16A3 Anticorps) via disruption of pyruvate rather than lactate export.
This study demonstrated that MCT1 was up regulation in ipsilateral site of brain afeter cerebral ischemia.
The soleus, liver and heart were the main tissues that showed improved the MCT1 mRNA expression, indicating its important role in controlling MLSS concentration in mice.
Exercise-induced changes in tumour LDH-B (Montrer LDHB Anticorps) and MCT1 expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice
Chronic lactate administration after exercise increases MCT1 protein expression, which can be involved in the regulation of the observed increase in muscle glycogen (Montrer GYS1 Anticorps) storage after exercise training.
This study showed that mouse MCT1, MCT2 (Montrer SLC16A7 Anticorps), and MCT4 (Montrer SLC16A3 Anticorps) are expressed in the PNS. While DRG neurons express MCT1, myelinating Schwann cells.
These data for the first time demonstrate that MCT1 is critical for regeneration of both sensory and motor axons in mice following sciatic nerve crush
Study demonstrated that PTEN (Montrer PTEN Anticorps) loss and MCT-1 induction synergistically promoted the neoplastic multinucleation via the Src (Montrer SRC Anticorps)/p190B (Montrer ARHGAP5 Anticorps) signaling activation.
in Parkinson's disease, the levels of MCT1, MCT2 (Montrer SLC16A7 Anticorps) and GLUT1 (Montrer SLC2A1 Anticorps) is not changed following dopaminergic neurodegeneration
Reinitiation complexes involving initiation factors eIF2D (Montrer EIF2D Anticorps), MCT-1 (Montrer CMA1 Anticorps), and DENR (Montrer DENR Anticorps) controls the translation of a large fraction of mammalian cellular mRNAs.
Increased miR (Montrer MLXIP Anticorps)-210 and concomitant decreased ISCU (Montrer ISCU Anticorps) RNA levels were found in ~40% of tumors and this was significantly associated with HIF-1alpha (Montrer HIF1A Anticorps) and CAIX (Montrer CA9 Anticorps), but not MCT1 (Montrer CMA1 Anticorps) or MCT4 (Montrer SLC16A4 Anticorps), over-expression.
Data show that metastasis-associated in colon cancer-1 (MACC1 (Montrer MACC1 Anticorps)) and monocarboxylate transporter 1 (MCT1) are highly expressed in gastric cancer indicating poor prognosis.
AA genotype of the MCT1 (Montrer CMA1 Anticorps) T1470A polymorphism is over-represented in wrestlers compared with controls and is associated with lower blood lactate concentrations after 30-s Wingate Anaerobic test and during intermittent sprint tests in Japanese wrestlers
MCT1 (Montrer CMA1 Anticorps) and MCT4 (Montrer SLC16A4 Anticorps) expression levels were associated with worse prognosis and shorter overall survival.
MCT1 (Montrer CMA1 Anticorps) may be acting as an uptake transporter and MCT4 (Montrer SLC16A4 Anticorps) as an efflux system across the basolateral membrane for ferulic acid, and that this process is stimulated by butyric acid.
After indirect co-culture, OP was increased in the BxPc-3 and Panc-1 cells; correspondingly, succinate dehydrogenase (Montrer SDHA Anticorps), FH and MCT (Montrer MCAT Anticorps) expression were increased. After the MCT1 (Montrer CMA1 Anticorps)-specific inhibitor removed 'tumor-stromal' metabolic coupling, the migration and invasion abilities of the pancreatic cancer cells were decreased.
Data suggest that inhibition of mnocarboxylate transporters MCT1 (Montrer CMA1 Anticorps) and MCT4 (Montrer SLC16A4 Anticorps) may have clinical relevance in pancreatic ductal adenocarcinoma (PDAC).
Results found that MCT (Montrer MCAT Anticorps) contributes to endothelial cell growth and tube formation via up-regulation of angiopoietin-1 (Montrer ANGPT1 Anticorps) expression suggesting that MCT (Montrer MCAT Anticorps) plays an important role in pancreatic cancer angiogenesis and tumor growth via activating the angiopoietin-1 (Montrer ANGPT1 Anticorps) pathway.
The targeting of MCT1 (Montrer CMA1 Anticorps) and PFKFB3 (Montrer PFKFB3 Anticorps) regulated cell proliferation.
Data indicate that monocarboxylate transporters (MCTs1-4) were all found to be expressed in brains of embryos, and were localized in both neurons and astrocyte.
This study confirmed age-dependent changes of MCT1 expression in the rumen epithelium of newborn calves and showed that its expression might be affected by liquid feed type.
These findings show that MCT 1 increases with the development of rumen function and also in adult animals MCT 1 may change with the feeding.
The expression and distribution of monocarboxylate transporter 1 along the gastrointestinal tract of calves suggest it may play a role in transport of short chain fatty acids and their metabolites.
The results show that monocarboxylate transporter 1 (MCT1) is a major route for short chain fatty acids (SCFA) efflux across the basolateral membrane of bovine large intestine and that it could play a role in the regulation of intracellular pH.
Data suggest that expression of MCT1 in intestinal mucosa can be altered by diet; here, expression of MCT1 is down-regulated in colonic mucosa by high-protein diet and appears to be linked to fermentation of dietary proteins by intestinal microbes.
MCT1-mRNA showed a higher expression in the ileum; feeding inulin-coated butyrate resulted in an increased ileal surface; delivery of butyrate to the colon requires a more resistant inulin-coating.
The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.
malignant T cell amplified sequence 1
, malignant T cell-amplified sequence 1
, malignant T-cell-amplified sequence 1
, multiple copies T-cell malignancies
, multiple copies T-cell malignancies 1
, Malignant T cell amplified sequence 1-A
, malignant T cell-amplified sequence 1-A
, malignant T-cell-amplified sequence 1-A
, MCT 1
, monocarboxylate transporter 1
, solute carrier family 16 (monocarboxylic acid transporters), member 1
, solute carrier family 16 member 1
, solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
, solute carrier 16 (monocarboxylic acid transporter), member 1
, monocarboxylate transporter 1a