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transports lactic acid and other monocarboxylic acids. De plus, nous expédions Malignant T Cell Amplified Sequence 1 Protéines (13) et Malignant T Cell Amplified Sequence 1 Kits (7) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal MCTS1 Primary Antibody pour EIA, WB - ABIN453186
Kasiappan, Shih, Chu, Chen, Liu, Huang, Choy, Shu, Din, Chu, Hsu: Loss of p53 and MCT-1 overexpression synergistically promote chromosome instability and tumorigenicity. dans Molecular cancer research : MCR 2009
Show all 3 references for ABIN453186
Chicken Polyclonal MCTS1 Primary Antibody pour WB - ABIN2779047
Shi, Levenson, Gartenhaus: Identification and characterization of a novel enhancer for the human MCT-1 oncogene promoter. dans Journal of cellular biochemistry 2003
Human Polyclonal MCTS1 Primary Antibody pour WB - ABIN152954
Kumar, Kant, Singh et al.: Antitumor and chemosensitizing action of dichloroacetate implicates modulation of tumor microenvironment: a role of reorganized glucose metabolism, cell survival regulation and macrophage ... dans Toxicology and applied pharmacology 2013
Human Polyclonal MCTS1 Primary Antibody pour WB - ABIN4891880
Haas, Ngo, Li, Schleich, Qu, Vanyai, Cullen, Cardona-Alberich, Gladwyn-Ng, Pagnamenta, Taylor, Stewart, Kini, Duncan, Teleman, Keays, Heng: De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation. dans Cell reports 2016
MCT1 inhibition impairs proliferation of glycolytic breast cancer cells co-expressing MCT1 and MCT4 (Montrer SLC16A3 Anticorps) via disruption of pyruvate rather than lactate export.
This study demonstrated that MCT1 was up regulation in ipsilateral site of brain afeter cerebral ischemia.
The soleus, liver and heart were the main tissues that showed improved the MCT1 mRNA expression, indicating its important role in controlling MLSS concentration in mice.
Exercise-induced changes in tumour LDH-B (Montrer LDHB Anticorps) and MCT1 expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice
Chronic lactate administration after exercise increases MCT1 protein expression, which can be involved in the regulation of the observed increase in muscle glycogen (Montrer GYS1 Anticorps) storage after exercise training.
This study showed that mouse MCT1, MCT2 (Montrer SLC16A7 Anticorps), and MCT4 (Montrer SLC16A3 Anticorps) are expressed in the PNS. While DRG neurons express MCT1, myelinating Schwann cells.
These data for the first time demonstrate that MCT1 is critical for regeneration of both sensory and motor axons in mice following sciatic nerve crush
Study demonstrated that PTEN (Montrer PTEN Anticorps) loss and MCT-1 induction synergistically promoted the neoplastic multinucleation via the Src (Montrer SRC Anticorps)/p190B (Montrer ARHGAP5 Anticorps) signaling activation.
in Parkinson's disease, the levels of MCT1, MCT2 (Montrer SLC16A7 Anticorps) and GLUT1 (Montrer SLC2A1 Anticorps) is not changed following dopaminergic neurodegeneration
results suggest that a reduction in mitochondria is a result, rather than the cause, of the metabolic deficiency observed in Basigin-null mice, and likely occurs because of reduced metabolic activity in the absence of MCT1 expression.
After indirect co-culture, OP was increased in the BxPc-3 and Panc-1 cells; correspondingly, succinate dehydrogenase (Montrer SDHA Anticorps), FH and MCT (Montrer MCAT Anticorps) expression were increased. After the MCT1 (Montrer CMA1 Anticorps)-specific inhibitor removed 'tumor-stromal' metabolic coupling, the migration and invasion abilities of the pancreatic cancer cells were decreased.
Data suggest that inhibition of mnocarboxylate transporters MCT1 (Montrer CMA1 Anticorps) and MCT4 (Montrer SLC16A4 Anticorps) may have clinical relevance in pancreatic ductal adenocarcinoma (PDAC).
Results found that MCT (Montrer MCAT Anticorps) contributes to endothelial cell growth and tube formation via up-regulation of angiopoietin-1 (Montrer ANGPT1 Anticorps) expression suggesting that MCT (Montrer MCAT Anticorps) plays an important role in pancreatic cancer angiogenesis and tumor growth via activating the angiopoietin-1 (Montrer ANGPT1 Anticorps) pathway.
The targeting of MCT1 (Montrer CMA1 Anticorps) and PFKFB3 (Montrer PFKFB3 Anticorps) regulated cell proliferation.
MCT1 (Montrer CMA1 Anticorps) expression associates with the SCC (Montrer CYP11A1 Anticorps) type and metastatic behavior of AC, whereas MCT4 (Montrer SLC16A4 Anticorps) expression concomitantly increases from in situ SCC (Montrer CYP11A1 Anticorps) to invasive SCC (Montrer CYP11A1 Anticorps) and is significantly associated with the AC type. Consistently, FOXM1 (Montrer FOXM1 Anticorps) expression is statistically associated with MCT1 (Montrer CMA1 Anticorps) positivity in SCC (Montrer CYP11A1 Anticorps), whereas the expression of FOXO3a (Montrer FOXO3 Anticorps), a FOXM1 (Montrer FOXM1 Anticorps) functional antagonist, is linked to MCT1 (Montrer CMA1 Anticorps) negativity
This study investigated MCT1 (Montrer CMA1 Anticorps) protein abundance in various human intestinal tissues.
MCT1 (Montrer CMA1 Anticorps) affects the plasma lactate decrease .
The aim of this study was to investigate the association between the MCT1 (Montrer CMA1 Anticorps) A1470T polymorphism and fat-free (Montrer VPS51 Anticorps) mass in young Italian elite soccer players. The MCT1 (Montrer CMA1 Anticorps) T allele is associated with the percentage of fat-free (Montrer VPS51 Anticorps) mass in young elite male soccer players.
MCT1 (Montrer CMA1 Anticorps) inhibition impairs proliferation of glycolytic breast cancer cells co-expressing MCT1 (Montrer CMA1 Anticorps) and MCT4 (Montrer SLC16A4 Anticorps) via disruption of pyruvate rather than lactate export.
MCT1 (Montrer CMA1 Anticorps) expression was not clearly associated with overall or disease-free survival. MCT4 (Montrer SLC16A4 Anticorps) and CD147 expression correlate with worse prognosis across many cancer types. These results warrant further investigation of these associations.
Data indicate that monocarboxylate transporters (MCTs1-4) were all found to be expressed in brains of embryos, and were localized in both neurons and astrocyte.
This study confirmed age-dependent changes of MCT1 expression in the rumen epithelium of newborn calves and showed that its expression might be affected by liquid feed type.
These findings show that MCT 1 increases with the development of rumen function and also in adult animals MCT 1 may change with the feeding.
The expression and distribution of monocarboxylate transporter 1 along the gastrointestinal tract of calves suggest it may play a role in transport of short chain fatty acids and their metabolites.
The results show that monocarboxylate transporter 1 (MCT1) is a major route for short chain fatty acids (SCFA) efflux across the basolateral membrane of bovine large intestine and that it could play a role in the regulation of intracellular pH.
Data suggest that expression of MCT1 in intestinal mucosa can be altered by diet; here, expression of MCT1 is down-regulated in colonic mucosa by high-protein diet and appears to be linked to fermentation of dietary proteins by intestinal microbes.
MCT1-mRNA showed a higher expression in the ileum; feeding inulin-coated butyrate resulted in an increased ileal surface; delivery of butyrate to the colon requires a more resistant inulin-coating.
The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.
malignant T cell amplified sequence 1
, malignant T cell-amplified sequence 1
, malignant T-cell-amplified sequence 1
, multiple copies T-cell malignancies
, multiple copies T-cell malignancies 1
, Malignant T cell amplified sequence 1-A
, malignant T cell-amplified sequence 1-A
, malignant T-cell-amplified sequence 1-A
, MCT 1
, monocarboxylate transporter 1
, solute carrier family 16 (monocarboxylic acid transporters), member 1
, solute carrier family 16 member 1
, solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
, solute carrier 16 (monocarboxylic acid transporter), member 1
, monocarboxylate transporter 1a