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MTA1 encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. De plus, nous expédions MTA1 Protéines (7) et MTA1 Kits (1) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 112 products:
Human Monoclonal MTA1 Primary Antibody pour IF, WB - ABIN393781
Van Rechem, Boulay, Pinte, Stankovic-Valentin, Guérardel, Leprince: Differential regulation of HIC1 target genes by CtBP and NuRD, via an acetylation/SUMOylation switch, in quiescent versus proliferating cells. dans Molecular and cellular biology 2010
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Human Monoclonal MTA1 Primary Antibody pour WB - ABIN393787
Li, Ohshiro, Khan, Kumar: Requirement of MTA1 in ATR-mediated DNA damage checkpoint function. dans The Journal of biological chemistry 2010
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Human Polyclonal MTA1 Primary Antibody pour WB - ABIN1881556
Zhu, Guo, Li, Ding, Chen: Metastasis-associated protein 1 nuclear expression is associated with tumor progression and clinical outcome in patients with non-small cell lung cancer. dans Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010
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Chicken Polyclonal MTA1 Primary Antibody pour WB - ABIN2780234
Kumar, Wang, Mazumdar, Talukder, Mandal, Yang, Bagheri-Yarmand, Sahin, Hortobagyi, Adam, Barnes, Vadlamudi: A naturally occurring MTA1 variant sequesters oestrogen receptor-alpha in the cytoplasm. dans Nature 2002
Human Polyclonal MTA1 Primary Antibody pour ELISA, WB - ABIN184623
Toh, Pencil, Nicolson: A novel candidate metastasis-associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression, and protein analyses. dans The Journal of biological chemistry 1994
MTA1 is up-regulated in CRC (Montrer CALR Anticorps); its expression is inversely associated with lymphatic metastases and the expression of VEGFC (Montrer VEGFC Anticorps), VEGFD (Montrer Figf Anticorps) and VEGFR3 (Montrer FLT4 Anticorps)
We revealed a new molecular mechanism of MTA1-mediated invasion and metastasis in lung cancer through downstream target EpCAM (Montrer EPCAM Anticorps), and interfering with EpCAM (Montrer EPCAM Anticorps) function may be a novel therapeutic strategy for treatment of MTA1-overexpressing lung carcinoma
MTA1 plays an important role in Epithelial-to-mesenchymal transition (EMT (Montrer ITK Anticorps)) to promote metastasis via suppressing E-cadherin (Montrer CDH1 Anticorps) expression, resulting in a poor prognosis in MPM. MTA1 is a novel biomarker and indicative of a poor prognosis in MPM patients
Inhibition of MTA1 by ERalpha (Montrer ESR1 Anticorps) contributes to protection hepatocellular carcinoma from tumor proliferation and metastasis
protein abundance of YB-1 (Montrer YBX1 Anticorps) and MTA1, irrespective of DNA or mRNA status, can predict for prostate cancer relapse and uncover a vast underappreciated repository of biomarkers regulated at the level of protein expression.
RNAi aiming at MTA1 can effectively inhibit the expression of MTA1 in endometrial carcinoma Ishikawa cells
report demonstrates that miR (Montrer MLXIP Anticorps)-125a-3p inhibits the proliferation, migration, and invasion of NSCLC cells through down-regulation of MTA1
MTA1 drove a global decondensation of chromatin structure, it changed the expression of only a small proportion of genes.
MTA1 is associated with the aggressive nature of pituitary tumors and may be a potential therapeutic target in this tumor type.
MTA1 dysregulation in a subset of salivary gland cancer might promote aggressive phenotypes by compromising the tumor suppressor activity of ERbeta (Montrer ESR2 Anticorps)
Inhibition of MTA1 expression by in vivo siRNA treatment exacerbated the pathology of LPS (Montrer TLR4 Anticorps)-induced acute lung injury, by selectively promoting the expression of NF-kappaB (Montrer NFKB1 Anticorps)-regulated inflammatory cytokines.
MTA1 was regulated by HIF-1alpha (Montrer HIF1A Anticorps) in hypoxia circumstance to suppress osteoblast differentiation.
MTA1 levels were increased in monosodium urate crystal-induced inflammation.
The inhibition of MTA1 gene could depress the growth and metastasis of laryngeal squamous cell carcinoma in nude mice.
Data suggest that nuclear metastasis-associated protein 1 (MTA1) is a good marker for cancer differentiation diagnosis and a potential target for the treatment of cancers.
this study reports the potential signaling events related to up-regulation of metastasis associated protein 1 (Mta1), a master chromatin modifier, during mono-(2-ethylhexyl) phthalate (MEHP)-induced Sertoli cells injury.
MTA1 has an important role in the maintenance of circadian rhythmicity.
the MTA1/NFkappaB/FasL (Montrer FASL Anticorps) circuit may serve as an important defensive/repairing mechanism to help to control the germ cell quality after Sertoli cell injury.
MTA1 is a major contributor to prostate tumor malignant progression.
Data indicate that metastasis tumor antigen 1 (MTA1)-dependent stimulation of STAT3 transcription through action on the MTA1/STAT3/Pol II coactivator complex.
Findings suggest that Mta3-NuRD complex, inclding component HDAC1 (Montrer HDAC1 Anticorps), is essential for the initiation of primitive hematopoiesis.
This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene.
metastasis associated gene 1 protein
, metastasis-associated protein MTA1
, metastasis associated family, member 3
, metastasis-associated protein MTA3