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anti-Metastasis Associated in Colon Cancer 1 (MACC1) Anticorps

MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. De plus, nous expédions Metastasis Associated in Colon Cancer 1 Kits (7) et Metastasis Associated in Colon Cancer 1 Protéines (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
MACC1 346389 Q6ZN28
MACC1 238455  
MACC1 314539  
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Top anti-Metastasis Associated in Colon Cancer 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 35 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué EIA, IHC (p), WB Immunohistochemistry of MACC1 in human liver tissue with this product at 2.5 μg/ml. Western blot analysis of MACC1 in mouse liver tissue lysate with this product at (A) 1 and (B) 2 μg/ml. 0.1 mg Connectez-vous pour afficher 8 to 10 Days
357,50 €
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human stomach tissue labeled with Anti-MACC1Polyclonal Antibody, Unconjugated (ABIN706526) followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-MACC1 Polyclonal Antibody, Unconjugated (ABIN706526) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Connectez-vous pour afficher 5 to 7 Days
277,90 €
Détails
Humain Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 12 Days
194,82 €
Détails
Humain Lapin Inconjugué WB Western blot analysis of MACC1 expression in HEK293T (A), H9C2 (B) whole cell lysates. 200 μL Connectez-vous pour afficher 7 to 8 Days
510,71 €
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Western blot analysis of MACC1 in mouse liver tissue lysate with MACC1 antibody at (A) 1 and (B) 2 µg/ml. 50 μg Connectez-vous pour afficher 8 to 10 Days
517,00 €
Détails
Humain Lapin Inconjugué WB, ICC, IHC (p), IHC (fro) 100 μg Connectez-vous pour afficher 7 to 10 Days
404,38 €
Détails
Humain Lapin Alexa Fluor 647 IF (p)   100 μL Connectez-vous pour afficher 14 to 17 Days
366,11 €
Détails
Humain Lapin Alexa Fluor 350 IF (p)   100 μL Connectez-vous pour afficher 14 to 17 Days
366,11 €
Détails
Humain Lapin Alexa Fluor 555 IF (p)   100 μL Connectez-vous pour afficher 14 to 17 Days
366,11 €
Détails
Humain Lapin Alexa Fluor 488 IF (p)   100 μL Connectez-vous pour afficher 14 to 17 Days
366,11 €
Détails

MACC1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité
Human , , , ,

Mouse (Murine) , , , ,

Rat (Rattus) , , , ,

anti-Metastasis Associated in Colon Cancer 1 Anticorps mieux référencés

  1. Human Polyclonal MACC1 Primary Antibody pour EIA,IHC (p) - ABIN500214 : Boardman: Overexpression of MACC1 leads to downstream activation of HGF/MET and potentiates metastasis and recurrence of colorectal cancer. dans Genome medicine 2009 (PubMed)
    Show all 4 references for ABIN500214

  2. Human Polyclonal MACC1 Primary Antibody pour WB,IHC (p) - ABIN706526 : Sun, Li, Dai, Tan, Zhao, Li, Wang: Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells. dans Molecular medicine reports 2015 (PubMed)

Plus d’anticorps contre Metastasis Associated in Colon Cancer 1 partenaires d’interaction

Human Metastasis Associated in Colon Cancer 1 (MACC1) interaction partners

  1. In renal cell carcinoma (Montrer MOK Anticorps), positive MACC1 expression was found to significantly correlate with distant metastasis and TNM (Montrer ODZ1 Anticorps) stage. patients with higher MACC1 expression had a significantly lower disease-free rate

  2. conclusion, high MACC1 expression may serve as a prognostic biomarker to guide individualized management in clinical practice for digestive system neoplasms.

  3. MACC1 promotes vasculogenic mimicry in gastric cancer by regulating the HGF/c-Met-TWIST1 (Montrer TWIST1 Anticorps)/2 signaling pathway.

  4. MACC1 expression predicts survival outcome in colorectal cancer patients.

  5. These results suggested that MACC1 leads to a poor prognosis in HCC (Montrer FAM126A Anticorps), partly by promoting proliferation via enhancement in glucose metabolism by HK2 (Montrer HK2 Anticorps).

  6. our findings provide some novel insights into the role of MACC1 in breast cancer, indicating that it plays different roles in breast and several other cancers.

  7. MACC1 overexpression predicted worse prognosis after liver resection, which was attributed to the repression of HCC (Montrer FAM126A Anticorps) cell apoptosis via a molecular mechanism in which MACC1 accelerated the activation of the HGF/c-MET/PI3K (Montrer PIK3CA Anticorps)/AKT (Montrer AKT1 Anticorps) pathway

  8. MACC1 expression might be closely related to carcinogenesis, clinical biological behaviors, and prognosis of gallbladder adenocarcinoma.

  9. Silencing of MACC1 was found to enhance the apoptosis.

  10. Levels of circulating MACC1 transcripts in plasma of gastric cancer patients are of diagnostic value and are prognostic for patient survival.

Mouse (Murine) Metastasis Associated in Colon Cancer 1 (MACC1) interaction partners

  1. Data suggest a critical role for MACC1 in lymphatic dissemination of GC, providing evidence that MACC1 upregulated VEGF-C/VEGF-D secretion to promote lymphangiogenesis via c-Met signaling.

  2. HGF, MACC1 and C-met genes involve into malignant cervical tumors occurrence, development and prognosis, and might become potential molecular target therapy site of cervical cancer

  3. MACC1 has a role in colorectal cancer and can be used for imaging in xenografts

  4. MACC1 will be useful for the identification of poor prognosis subjects with colorectal cancer and is a promising new target for intervention in metastasis formation.

Metastasis Associated in Colon Cancer 1 (MACC1) profil antigène

Profil protéine

MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009

Gene names and symbols associated with MACC1

  • metastasis associated in colon cancer 1 (MACC1) anticorps
  • metastasis associated in colon cancer 1 (Macc1) anticorps
  • 7a5 anticorps
  • 4732474O15Rik anticorps
  • Gm267 anticorps
  • RGD1309838 anticorps
  • SH3BP4L anticorps

Protein level used designations for MACC1

SH3 domain-containing protein 7a5 , metastasis-associated in colon cancer protein 1 , putative binding protein 7a5

GENE ID SPECIES
346389 Homo sapiens
238455 Mus musculus
314539 Rattus norvegicus
521867 Bos taurus
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